메뉴 건너뛰기




Volumn 45, Issue 9, 2012, Pages 841-850

Efficacy of the dietary histone deacetylase inhibitor butyrate alone or in combination with vitamin A against proliferation of MCF-7 human breast cancer cells

Author keywords

Breast cancer; Butyric acid; Epigenetics; MCF 7 cells; Vitamin A

Indexed keywords

BUTYRIC ACID; COMPLEMENTARY DNA; DNA; GENOMIC DNA; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; RETINOID; RETINOL PALMITATE; RNA; SHORT CHAIN FATTY ACID;

EID: 84865397256     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2012007500103     Document Type: Article
Times cited : (15)

References (38)
  • 1
    • 0003661910 scopus 로고    scopus 로고
    • WHO-World Health Organization. Geneva: World Health Organization
    • WHO-World Health Organization. World Health Statistics. Geneva: World Health Organization; 2008.
    • (2008) World Health Statistics
  • 2
    • 84255191349 scopus 로고    scopus 로고
    • Epigenetic regulation of retinoic acid receptor beta2 gene in the initiation of breast cancer
    • Sun J, Xu X, Liu J, Liu H, Fu L, Gu L. Epigenetic regulation of retinoic acid receptor beta2 gene in the initiation of breast cancer. Med Oncol 2011; 28: 1311-1318.
    • (2011) Med Oncol , vol.28 , pp. 1311-1318
    • Sun, J.1    Xu, X.2    Liu, J.3    Liu, H.4    Fu, L.5    Gu, L.6
  • 3
    • 77149135270 scopus 로고    scopus 로고
    • Breast cancer epigenetics: From DNA methylation to microRNAs
    • Veeck J, Esteller M. Breast cancer epigenetics: from DNA methylation to microRNAs. J Mammary Gland Biol Neoplasia 2010; 15: 5-17.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 5-17
    • Veeck, J.1    Esteller, M.2
  • 4
    • 77957937450 scopus 로고    scopus 로고
    • Epigenetic modifications as therapeutic targets
    • Kelly TK, De Carvalho DD, Jones PA. Epigenetic modifications as therapeutic targets. Nat Biotechnol 2010; 28: 1069-1078.
    • (2010) Nat Biotechnol , vol.28 , pp. 1069-1078
    • Kelly, T.K.1    De Carvalho, D.D.2    Jones, P.A.3
  • 5
    • 39049156783 scopus 로고    scopus 로고
    • Nutritional genomic approaches to cancer prevention research
    • Ross SA. Nutritional genomic approaches to cancer prevention research. Exp Oncol 2007; 29: 250-256.
    • (2007) Exp Oncol , vol.29 , pp. 250-256
    • Ross, S.A.1
  • 6
    • 64249133886 scopus 로고    scopus 로고
    • Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: Efficacy of tributyrin, a butyric acid prodrug
    • Kuroiwa-Trzmielina J, de Conti A, Scolastici C, Pereira D, Horst MA, Purgatto E, et al. Chemoprevention of rat hepatocarcinogenesis with histone deacetylase inhibitors: efficacy of tributyrin, a butyric acid prodrug. Int J Cancer 2009; 124: 2520-2527.
    • (2009) Int J Cancer , vol.124 , pp. 2520-2527
    • Kuroiwa-Trzmielina, J.1    de Conti, A.2    Scolastici, C.3    Pereira, D.4    Horst, M.A.5    Purgatto, E.6
  • 7
    • 78049429911 scopus 로고    scopus 로고
    • Cancer chemoprevention by dietary polyphenols: Promising role for epigenetics
    • Link A, Balaguer F, Goel A. Cancer chemoprevention by dietary polyphenols: promising role for epigenetics. Biochem Pharmacol 2010; 80: 1771-1792.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1771-1792
    • Link, A.1    Balaguer, F.2    Goel, A.3
  • 8
    • 50949132079 scopus 로고    scopus 로고
    • Dietary manipulation of histone structure and function
    • Delage B, Dashwood RH. Dietary manipulation of histone structure and function. Annu Rev Nutr 2008; 28: 347-366.
    • (2008) Annu Rev Nutr , vol.28 , pp. 347-366
    • Delage, B.1    Dashwood, R.H.2
  • 9
    • 84864000201 scopus 로고    scopus 로고
    • Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis
    • de Conti A, Kuroiwa-Trzmielina J, Horst MA, Bassoli BK, Chagas CE, Purgatto E, et al. Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis. J Nutr Biochem 2012; 23: 860-866.
    • (2012) J Nutr Biochem , vol.23 , pp. 860-866
    • de Conti, A.1    Kuroiwa-Trzmielina, J.2    Horst, M.A.3    Bassoli, B.K.4    Chagas, C.E.5    Purgatto, E.6
  • 10
    • 0023515476 scopus 로고
    • Clinical pharmacology of sodium butyrate in patients with acute leukemia
    • Miller AA, Kurschel E, Osieka R, Schmidt CG. Clinical pharmacology of sodium butyrate in patients with acute leukemia. Eur J Cancer Clin Oncol 1987; 23: 1283-1287.
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 1283-1287
    • Miller, A.A.1    Kurschel, E.2    Osieka, R.3    Schmidt, C.G.4
  • 11
    • 0031954530 scopus 로고    scopus 로고
    • Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors
    • Conley BA, Egorin MJ, Tait N, Rosen DM, Sausville EA, Dover G, et al. Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors. Clin Cancer Res 1998; 4: 629-634.
    • (1998) Clin Cancer Res , vol.4 , pp. 629-634
    • Conley, B.A.1    Egorin, M.J.2    Tait, N.3    Rosen, D.M.4    Sausville, E.A.5    Dover, G.6
  • 13
    • 0033945786 scopus 로고    scopus 로고
    • Dietary butyrate inhibits NMUinduced mammary cancer in rats
    • Belobrajdic DP, McIntosh GH. Dietary butyrate inhibits NMUinduced mammary cancer in rats. Nutr Cancer 2000; 36: 217-223.
    • (2000) Nutr Cancer , vol.36 , pp. 217-223
    • Belobrajdic, D.P.1    McIntosh, G.H.2
  • 14
    • 39149108134 scopus 로고    scopus 로고
    • Anti-estrogenic actions of histone deacetylase inhibitors in MCF-7 breast cancer cells
    • De los Santos M, Martinez-Iglesias O, Aranda A. Anti-estrogenic actions of histone deacetylase inhibitors in MCF-7 breast cancer cells. Endocr Relat Cancer 2007; 14: 1021-1028.
    • (2007) Endocr Relat Cancer , vol.14 , pp. 1021-1028
    • De los Santos, M.1    Martinez-Iglesias, O.2    Aranda, A.3
  • 15
    • 0034868293 scopus 로고    scopus 로고
    • Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: Molecular mechanism involves an Sp1/Sp3 multiprotein complex
    • Walker GE, Wilson EM, Powell D, Oh Y. Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex. Endocrinology 2001; 142: 3817-3827.
    • (2001) Endocrinology , vol.142 , pp. 3817-3827
    • Walker, G.E.1    Wilson, E.M.2    Powell, D.3    Oh, Y.4
  • 16
    • 0942290420 scopus 로고    scopus 로고
    • P21(WAF1/ CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells
    • Chopin V, Toillon RA, Jouy N, Le Bourhis X. P21(WAF1/ CIP1) is dispensable for G1 arrest, but indispensable for apoptosis induced by sodium butyrate in MCF-7 breast cancer cells. Oncogene 2004; 23: 21-29.
    • (2004) Oncogene , vol.23 , pp. 21-29
    • Chopin, V.1    Toillon, R.A.2    Jouy, N.3    Le Bourhis, X.4
  • 17
    • 3042842755 scopus 로고    scopus 로고
    • How retinoids regulate breast cancer cell proliferation and apoptosis
    • Simeone AM, Tari AM. How retinoids regulate breast cancer cell proliferation and apoptosis. Cell Mol Life Sci 2004; 61: 1475-1484.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 1475-1484
    • Simeone, A.M.1    Tari, A.M.2
  • 18
    • 0036113703 scopus 로고    scopus 로고
    • Alterations in cellular retinol metabolism contribute to differential retinoid responsiveness in normal human mammary epithelial cells versus breast cancer cells
    • Hayden LJ, Satre MA. Alterations in cellular retinol metabolism contribute to differential retinoid responsiveness in normal human mammary epithelial cells versus breast cancer cells. Breast Cancer Res Treat 2002; 72: 95-105.
    • (2002) Breast Cancer Res Treat , vol.72 , pp. 95-105
    • Hayden, L.J.1    Satre, M.A.2
  • 19
    • 0037108867 scopus 로고    scopus 로고
    • Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer
    • Esteller M, Guo M, Moreno V, Peinado MA, Capella G, Galm O, et al. Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer. Cancer Res 2002; 62: 5902-5905.
    • (2002) Cancer Res , vol.62 , pp. 5902-5905
    • Esteller, M.1    Guo, M.2    Moreno, V.3    Peinado, M.A.4    Capella, G.5    Galm, O.6
  • 20
    • 0033805031 scopus 로고    scopus 로고
    • Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cells
    • Mira YL, Zheng WL, Kuppumbatti YS, Rexer B, Jing Y, Ong DE. Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cells. J Cell Physiol 2000; 185: 302-309.
    • (2000) J Cell Physiol , vol.185 , pp. 302-309
    • Mira, Y.L.1    Zheng, W.L.2    Kuppumbatti, Y.S.3    Rexer, B.4    Jing, Y.5    Ong, D.E.6
  • 21
    • 78649668597 scopus 로고    scopus 로고
    • Retinoids, retinoic acid receptors, and cancer
    • Tang XH, Gudas LJ. Retinoids, retinoic acid receptors, and cancer. Annu Rev Pathol 2011; 6: 345-364.
    • (2011) Annu Rev Pathol , vol.6 , pp. 345-364
    • Tang, X.H.1    Gudas, L.J.2
  • 22
    • 12444307577 scopus 로고    scopus 로고
    • Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity
    • Farias EF, Ong DE, Ghyselinck NB, Nakajo S, Kuppumbatti YS, Lopez R. Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity. J Natl Cancer Inst 2005; 97: 21-29.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 21-29
    • Farias, E.F.1    Ong, D.E.2    Ghyselinck, N.B.3    Nakajo, S.4    Kuppumbatti, Y.S.5    Lopez, R.6
  • 23
    • 51849099492 scopus 로고    scopus 로고
    • The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells
    • Spurling CC, Suhl JA, Boucher N, Nelson CE, Rosenberg DW, Giardina C. The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells. Nutr Cancer 2008; 60: 692-702.
    • (2008) Nutr Cancer , vol.60 , pp. 692-702
    • Spurling, C.C.1    Suhl, J.A.2    Boucher, N.3    Nelson, C.E.4    Rosenberg, D.W.5    Giardina, C.6
  • 24
    • 0036558155 scopus 로고    scopus 로고
    • Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer
    • Sirchia SM, Ren M, Pili R, Sironi E, Somenzi G, Ghidoni R, et al. Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. Cancer Res 2002; 62: 2455-2461.
    • (2002) Cancer Res , vol.62 , pp. 2455-2461
    • Sirchia, S.M.1    Ren, M.2    Pili, R.3    Sironi, E.4    Somenzi, G.5    Ghidoni, R.6
  • 25
    • 0242594496 scopus 로고    scopus 로고
    • Alterations in the expression and modification of histones in the liver after injury
    • Jeong J, Adamson LK, Hatam R, Greenhalgh DG, Cho K. Alterations in the expression and modification of histones in the liver after injury. Exp Mol Pathol 2003; 75: 256-264.
    • (2003) Exp Mol Pathol , vol.75 , pp. 256-264
    • Jeong, J.1    Adamson, L.K.2    Hatam, R.3    Greenhalgh, D.G.4    Cho, K.5
  • 27
    • 33845622958 scopus 로고    scopus 로고
    • Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT)
    • Alyaqoub FS, Tao L, Kramer PM, Steele VE, Lubet RA, Gunning WT, et al. Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT). Carcinogenesis 2007; 28: 124-129.
    • (2007) Carcinogenesis , vol.28 , pp. 124-129
    • Alyaqoub, F.S.1    Tao, L.2    Kramer, P.M.3    Steele, V.E.4    Lubet, R.A.5    Gunning, W.T.6
  • 29
    • 0028174443 scopus 로고
    • Inhibition of microsomal 17 beta-hydroxysteroid oxidoreduction activities in rat liver by all-trans-, 9-cis-and 13-cis-retinoic acid
    • Murray M, Butler AM, Martini R. Inhibition of microsomal 17 beta-hydroxysteroid oxidoreduction activities in rat liver by all-trans-, 9-cis-and 13-cis-retinoic acid. Biochim Biophys Acta 1994; 1222: 227-233.
    • (1994) Biochim Biophys Acta , vol.1222 , pp. 227-233
    • Murray, M.1    Butler, A.M.2    Martini, R.3
  • 30
    • 15944406847 scopus 로고    scopus 로고
    • Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells
    • Mongan NP, Gudas LJ. Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells. Mol Cancer Ther 2005; 4: 477-486.
    • (2005) Mol Cancer Ther , vol.4 , pp. 477-486
    • Mongan, N.P.1    Gudas, L.J.2
  • 31
    • 70349319850 scopus 로고    scopus 로고
    • Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells
    • Rahim R, Strobl JS. Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells. Anticancer Drugs 2009; 20: 736-745.
    • (2009) Anticancer Drugs , vol.20 , pp. 736-745
    • Rahim, R.1    Strobl, J.S.2
  • 32
    • 34250171437 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Signalling towards p21cip1/waf1
    • Ocker M, Schneider-Stock R. Histone deacetylase inhibitors: signalling towards p21cip1/waf1. Int J Biochem Cell Biol 2007; 39: 1367-1374.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1367-1374
    • Ocker, M.1    Schneider-Stock, R.2
  • 33
    • 32544452237 scopus 로고    scopus 로고
    • Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins
    • Tryndyak VP, Kovalchuk O, Pogribny IP. Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. Cancer Biol Ther 2006; 5: 65-70.
    • (2006) Cancer Biol Ther , vol.5 , pp. 65-70
    • Tryndyak, V.P.1    Kovalchuk, O.2    Pogribny, I.P.3
  • 34
    • 43149125426 scopus 로고    scopus 로고
    • Genome-wide mapping and characterization of hypomethylated sites in human tissues and breast cancer cell lines
    • Shann YJ, Cheng C, Chiao CH, Chen DT, Li PH, Hsu MT. Genome-wide mapping and characterization of hypomethylated sites in human tissues and breast cancer cell lines. Genome Res 2008; 18: 791-801.
    • (2008) Genome Res , vol.18 , pp. 791-801
    • Shann, Y.J.1    Cheng, C.2    Chiao, C.H.3    Chen, D.T.4    Li, P.H.5    Hsu, M.T.6
  • 35
    • 0034680012 scopus 로고    scopus 로고
    • Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells
    • Arapshian A, Kuppumbatti YS, Lopez R. Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells. Oncogene 2000; 19: 4066-4070.
    • (2000) Oncogene , vol.19 , pp. 4066-4070
    • Arapshian, A.1    Kuppumbatti, Y.S.2    Lopez, R.3
  • 36
    • 84856225906 scopus 로고    scopus 로고
    • Prognostic significance of gene-specific promoter hypermethylation in breast cancer patients
    • Cho YH, Shen J, Gammon MD, Zhang YJ, Wang Q, Gonzalez K, et al. Prognostic significance of gene-specific promoter hypermethylation in breast cancer patients. Breast Cancer Res Treat 2012; 131: 197-205.
    • (2012) Breast Cancer Res Treat , vol.131 , pp. 197-205
    • Cho, Y.H.1    Shen, J.2    Gammon, M.D.3    Zhang, Y.J.4    Wang, Q.5    Gonzalez, K.6
  • 38
    • 2942538294 scopus 로고    scopus 로고
    • Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer
    • Arapshian A, Bertran S, Kuppumbatti YS, Nakajo S, Lopez R. Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer. Mol Cancer 2004; 3: 13.
    • (2004) Mol Cancer , vol.3 , pp. 13
    • Arapshian, A.1    Bertran, S.2    Kuppumbatti, Y.S.3    Nakajo, S.4    Lopez, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.