Enhanced oral bioavailability of a cancer preventive agent (SR13668) by employing polymeric nanoparticles with high drug loading

Journal of Pharmaceutical Sciences

Volumn 101, Issue 10, 2012, Pages 3877-3885

  Shen, Hao ^a   Banerjee, Aryamitra A ^b   Mlynarska, Paulina ^a   Hautman, Mathew ^c   Hong, Seungpyo ^b   Kapetanovic, Izet M ^d   Lyubimov, Alexander V ^b   Liu, Ying ^a,b  

^a 1120 Science and Engineering Offices   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c Center for Biomedical Testing   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Bioavailability; Cancer chemoprevention; Nanoparticles; Nanoprecipitation; Scalable; Spray drying; Stability

Indexed keywords

2,10 DICARBETHOXY 6 METHOXY 5,7 DIHYDRO INDOLO (2,3 B)CARBAZOLE; ANTINEOPLASTIC AGENT; LABRASOL; NANOPARTICLE; POLYGLACTIN; SR 13668; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; DRUG STABILITY; IN VITRO STUDY; KINETICS; MOUSE; NANOENCAPSULATION; NONHUMAN; PRECIPITATION; SPRAY DRYING; SUSPENSION;

EID: 84865392213     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23269     Document Type: Article

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