Block copolymer micelles formed in supercritical fluid can become water-dispensable nanoparticles: Polyethylene glycol - Block-poly(ε- caprolactone) in trifluoromethane

Industrial and Engineering Chemistry Research

Volumn 48, Issue 4, 2009, Pages 1928-1932

  Tyrrell, Zachary ^a   Winoto, ^a   Shen, Youqing ^a   Radosz, Maciej ^a  

^a UNIVERSITY OF WYOMING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOCK COPOLYMER MICELLES; CAPROLACTONE; DRUG-DELIVERY; FREEZE DRYING; HYDROPHOBIC BLOCKS; LASER LIGHT SCATTERINGS; MICELLAR STRUCTURES; POLY(ETHYLENE GLYCOL); RESIDUAL ORGANIC SOLVENTS; SUPERCRITICAL TRIFLUOROMETHANE; TEMPERATURE PHASE; TRIFLUOROMETHANE;

BLOCK COPOLYMERS; DIALYSIS; EFFLUENT TREATMENT; ETHYLENE; ETHYLENE GLYCOL; LIGHT SCATTERING; MICELLES; NANOPARTICLES; ORGANIC POLYMERS; PHASE DIAGRAMS; PHOTORESISTS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; SUPERCRITICAL FLUIDS;

ORGANIC SOLVENTS;

EID: 61849115683     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie801472n     Document Type: Article

References (26)

1. Kabanov, A. V.; Alakhov, V. Y. Amphiphilic Block Copolymers: Self-Assembly and Applications; Elsevier: Amsterdam, 1997.
2. Alakhov, V. Y.; Moskaleva, E. Y.; Batrakova, E. V.; Kabanov, A. V. Hypersensitization of Multidrug Resistant Human Ovarian Carcinoma Cells by Pluronic P85 Block Copolymer. Bioconjugate Chem. 1996, 7, 209.
3. Kabanov, A. V.; Nazarova, I. R.; Astafieva, I. R.; Batrakova, E. V.; Alakhov, V. Y.; Yarostavov, A. A.; Kabanov, V. A. Micelle Formation and Solubilization of Fluorescent Probes in Poly(oxyethylene-b-oxypropylene-b- oxyethylene) Solutions. Macromolecules 1995, 28, 2303.
4. Kwon, G.; Naito, M.; Yokoyama, M.; Okano, T.; Sakurai, Y.; Kataoka, K. Block copolymer micelles for drug delivery: Loading and release of doxorubicin. J. Controlled Release 1997, 48, 195.
5. La, S. B.; Okano, T.; Kataoka, K. Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated polyethylene oxide)-poly(β-benzyl L-aspartate) block copolymer micelles. J. Pharm. Sci. 1996, 85, 85.
6. Kataoka, K.; Kwon, G.; Yokoyama, M.; Okano, T.; Sakurai, Y. Block copolymer micelles as vehicles for drug delivery. J. Controlled Release 1992, 24, 119.
7. Chiappetta, D. A.; Sosnik, A. Polyethylene oxide)-poly(propylene oxide) block copolymer micelles as drug delivery agents: Improved hydrosolubility, stability, and bioavailability of drugs. Eur. J. Pharm. Biopharm. 2007, 66, 303.
8. Allen, C.; Yu, Y.; Maysinger, D.; Eisenberg, A. Polycaprolactone - b-poly(ethylene Oxide) Block Copolymer Micelles as a Novel Drug Delivery Vehicle for Neurotrophic Agents FK506 and L-685,818. Bioconjugate Chem. 1998, 9, 564.
9. Vangeyte, P.; Gautier, S.; Jerome, R. About the methods of preparation of poly(ethylene oxide)-b-poly(ε-caprolactone) nanoparticles in water: Analysis by dynamic light scattering. Colloids Surf. A 2004, 242, 203.
10. Gaucher, G.; Dufresne, M.-H.; Sant, V. P.; Kang, N.; Maysinger, D.; Leroux, J. C. Block copolymer micelles: preparation, characterization and application in drug delivery. J. Controlled Release 2005, 109, 169.
11. Gref, R.; Minamitake, Y.; Peracchia, M. T.; Trubetskoy, V.; Torchilin, V.; Langer, R. Biodegradable long-circulating polymeric nanospheres. Science 1994, 263, 1600.
12. McHugh, M. A.; Krukonis, V. J. Supercritical Fluid Extraction, 2nd Edition; Butterworth-Heinemann: Boston, 1994.
13. York, P.; Kompella, U. B.; Shekunov, B. Y. Supercritical Fluid Technology for Drug Product Development; Marcel Dekker: New York, 2004.
14. Yeo, S. D.; Debenedetti, P. G.; Radosz, M.; Giesa, R.; Schmidt, H. W. Supercritical Antisolvent Process for a Series of Substituted Para-Linked Aromatic Polyamides. Macromolecules 1995, 28, 1316.
15. Lodge, T. P.; Bang, J.; Park, M. J.; Char, K. Origin of the Thermoreversible fee-bcc Transition in Block Copolymer Solutions. Phys. Rev. Lett. 2004, 92, 145501-1.
16. Winoto, W.; Adidharma, H.; Radosz, M. Micellization Temperature and Pressure for Polystyrene-block-polyisoprene in Subcritical and Supercritical Propane. Macromolecules 2006, 39, 8140.
17. Tan, S. P.; Winoto, W.; Radosz, M. Statistical Associating Fluid Theory of Homopolymers and Block Copolymers in Compressible Solutions: Polystyrene, Polybutadiene, Polyisoprene, Polystyrene-block-Polybutadiene, and Polystyrene-block-Polyisoprene in Propane. J Phys. Chem. C 2007, 111, 15752.
18. Radosz, M.; Shen, Y. International Patent WO 2008/030473 A2, 2008.
19. 2 Density-Induced Micellization Transition. Macromolecules 1998, 31, 7347.
20. 2. Macromolecules 2007, 40, 4917.
21. Wołoszczuk, S.; Banaszak, M.; Knychała, P; Radosz, M. Monte Carlo Phase Diagram of Symmetric Diblock Copolymer in Selective Solvent. Macromolecules 2008, 41, 5945.
22. Luszczyk, M.; Radosz, M. Temperature- and Pressure-Induced Crystallization and Melting of Tetracontane in Propane: Evidence of Retrograde Crystallization. J. Chem. Eng. Data 2003, 48, 226.
23. Chan, A. K. C.; Russo, P.; Radosz, M. Fluid-Liquid Equilibria in poly(ethyelene-co-hexene-1) + propane: A light-scattering probe of cloudpoint pressure and critical propane concentration. Fluid Phase Equilib. 2000, 173, 149.
24. Koga, T.; Zhou, S.; Chu, B.; Fulton, J. L.; Yang, S.; Ober, C. K.; Erman, B. New High Pressure Cell for Simultaneous Synchrotron Small-Angle X-ray Scattering and Laser Light Scattering Measurements. Rev. Sci. Instrum. 2001, 72, 2679.
25. Allen, C.; Yu, Y.; Maysinger, D.; Eisenberg, A. Nano-engineering block copolymer aggregates for drug delivery. Colloids Surf. B 1999, 16, 3.
26. Johnson, B. K.; Prud'homme, R. K. Mechanism for Rapid Self-Assembly of Block Copolymer Nanoparticles. Phys. Rev. Lett. 2003, 91, 118302-1.