Expression profile of early estradiol-responsive genes in cynomolgus macaque liver: Implications for drug-metabolizing enzymes

Drug Metabolism and Pharmacokinetics

Volumn 27, Issue 4, 2012, Pages 451-455

  Ise, Ryota ^a   Kito, Go ^b   Uno, Yasuhiro ^a,b  

^a SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Cynomolgus macaque; Cytochrome P450; Gene expression; Liver; Metabolic activity

Indexed keywords

DRUG METABOLIZING ENZYME; ESTRADIOL; OXIDOREDUCTASE; PLACEBO; TRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; CYP2A23 GENE; CYP2A24 GENE; CYP2A43 GENE; CYP2B6 GENE; CYP2C75 GENE; CYP2C76 GENE; CYP2D17 GENE; CYP2E1 GENE; CYP3A4 GENE; CYP3A5 GENE; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE LOCATION; GSTM5 GENE; LIVER; MACACA; MICROARRAY ANALYSIS; NONHUMAN; NOTE; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; QUANTITATIVE STUDY; TISSUE DISTRIBUTION; UPREGULATION;

EID: 84865384256     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.DMPK-11-NT-147     Document Type: Article

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