메뉴 건너뛰기




Volumn 425, Issue 2, 2012, Pages 244-249

Constitutive activation of the mTOR signaling pathway within the normal glomerulus

Author keywords

Glomerulus; Kidney; MTOR; Podocyte; Signaling

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; NEPHRIN; RAPAMYCIN; VASCULOTROPIN;

EID: 84865367034     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.075     Document Type: Article
Times cited : (8)

References (36)
  • 3
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: from growth signal integration to cancer, diabetes and ageing
    • Zoncu R., Efeyan A., Sabatini D.M. MTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 2011, 12:21-35.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 4
    • 57649096459 scopus 로고    scopus 로고
    • MTOR-what does it do?
    • Hall M.N. MTOR-what does it do?. Transplant. Proc. 2008, 40:S5-S8.
    • (2008) Transplant. Proc. , vol.40
    • Hall, M.N.1
  • 5
    • 81855169682 scopus 로고    scopus 로고
    • Mammalian TOR signaling to the AGC kinases
    • Su B., Jacinto E. Mammalian TOR signaling to the AGC kinases. Crit. Rev. Biochem. Mol. Biol. 2011, 46:527-547.
    • (2011) Crit. Rev. Biochem. Mol. Biol. , vol.46 , pp. 527-547
    • Su, B.1    Jacinto, E.2
  • 6
    • 3342895823 scopus 로고    scopus 로고
    • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
    • Sarbassov D.D., Ali S.M., Kim D.H., Guertin D.A., Latek R.R., Erdjument-Bromage H., Tempst P., Sabatini D.M. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 2004, 14:1296-1302.
    • (2004) Curr. Biol. , vol.14 , pp. 1296-1302
    • Sarbassov, D.D.1    Ali, S.M.2    Kim, D.H.3    Guertin, D.A.4    Latek, R.R.5    Erdjument-Bromage, H.6    Tempst, P.7    Sabatini, D.M.8
  • 8
    • 79952104568 scopus 로고    scopus 로고
    • MTOR couples cellular nutrient sensing to organismal metabolic homeostasis
    • Howell J.J., Manning B.D. MTOR couples cellular nutrient sensing to organismal metabolic homeostasis. Trends Endocrinol. Metab. 2011, 22:94-102.
    • (2011) Trends Endocrinol. Metab. , vol.22 , pp. 94-102
    • Howell, J.J.1    Manning, B.D.2
  • 9
    • 0038299000 scopus 로고    scopus 로고
    • Sirolimus: its discovery, biological properties, and mechanism of action
    • Sehgal S.N. Sirolimus: its discovery, biological properties, and mechanism of action. Transplant. Proc. 2003, 35:7S-14S.
    • (2003) Transplant. Proc. , vol.35
    • Sehgal, S.N.1
  • 12
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S., Loewith R., Hall M.N. TOR signaling in growth and metabolism. Cell 2006, 124:471-484.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 13
    • 34249284512 scopus 로고    scopus 로고
    • MTOR at the crossroads of T cell proliferation and tolerance
    • Mondino A., Mueller D.L. MTOR at the crossroads of T cell proliferation and tolerance. Semin. Immunol. 2007, 19:162-172.
    • (2007) Semin. Immunol. , vol.19 , pp. 162-172
    • Mondino, A.1    Mueller, D.L.2
  • 14
    • 34548178582 scopus 로고    scopus 로고
    • The Effects of mTOR-Akt Interactions on Anti-apoptotic Signaling in Vascular Endothelial Cells
    • Dormond O., Madsen J.C., Briscoe D.M. The Effects of mTOR-Akt Interactions on Anti-apoptotic Signaling in Vascular Endothelial Cells. J. Biol. Chem. 2007, 282:23679-23686.
    • (2007) J. Biol. Chem. , vol.282 , pp. 23679-23686
    • Dormond, O.1    Madsen, J.C.2    Briscoe, D.M.3
  • 15
    • 79957894759 scopus 로고    scopus 로고
    • The targeted podocyte
    • Fogo A.B. The targeted podocyte. J. Clin. Invest. 2011, 121:2142-2145.
    • (2011) J. Clin. Invest. , vol.121 , pp. 2142-2145
    • Fogo, A.B.1
  • 16
    • 46049086769 scopus 로고    scopus 로고
    • The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation
    • Walid S., Eisen R., Ratcliffe D.R., Dai K., Hussain M.M., Ojakian G.K. The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation. J. Cell. Physiol. 2008, 216:469-479.
    • (2008) J. Cell. Physiol. , vol.216 , pp. 469-479
    • Walid, S.1    Eisen, R.2    Ratcliffe, D.R.3    Dai, K.4    Hussain, M.M.5    Ojakian, G.K.6
  • 27
    • 71849091933 scopus 로고    scopus 로고
    • CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo
    • Dormond O., Contreras A.G., Meijer E., Datta D., Flynn E., Pal S., Briscoe D.M. CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo. J. Immunol. 2008, 181:8088-8095.
    • (2008) J. Immunol. , vol.181 , pp. 8088-8095
    • Dormond, O.1    Contreras, A.G.2    Meijer, E.3    Datta, D.4    Flynn, E.5    Pal, S.6    Briscoe, D.M.7
  • 29
    • 0141705466 scopus 로고    scopus 로고
    • Loss of Tsc1 or Tsc2 induces vascular endothelial growth factor production through mammalian target of rapamycin
    • El-Hashemite N., Walker V., Zhang H., Kwiatkowski D.J. Loss of Tsc1 or Tsc2 induces vascular endothelial growth factor production through mammalian target of rapamycin. Cancer Res. 2003, 63:5173-5177.
    • (2003) Cancer Res. , vol.63 , pp. 5173-5177
    • El-Hashemite, N.1    Walker, V.2    Zhang, H.3    Kwiatkowski, D.J.4
  • 32
    • 34250374471 scopus 로고    scopus 로고
    • Role of the VEGF-a signaling pathway in the glomerulus: evidence for crosstalk between components of the glomerular filtration barrier
    • Eremina V., Baelde H.J., Quaggin S.E. Role of the VEGF-a signaling pathway in the glomerulus: evidence for crosstalk between components of the glomerular filtration barrier. Nephron Physiol. 2007, 106:32-37.
    • (2007) Nephron Physiol. , vol.106 , pp. 32-37
    • Eremina, V.1    Baelde, H.J.2    Quaggin, S.E.3
  • 36
    • 0030641090 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine
    • Brown L.F., Detmar M., Claffey K., Nagy J.A., Feng D., Dvorak A.M., Dvorak H.F. Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine. EXS 1997, 79:233-269.
    • (1997) EXS , vol.79 , pp. 233-269
    • Brown, L.F.1    Detmar, M.2    Claffey, K.3    Nagy, J.A.4    Feng, D.5    Dvorak, A.M.6    Dvorak, H.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.