Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-β production

Journal of Biological Chemistry

Volumn 286, Issue 8, 2011, Pages 6117-6127

  Herskowitz, Jeremy H ^a   Seyfried, Nicholas T ^a   Gearing, Marla ^a   Kahn, Richard A ^a   Peng, Junmin ^a   Levey, Allan I ^a   Lah, James J ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; BINDING PARTNERS; CELL SURFACE RECEPTORS; COILED COIL; CYTOPLASMIC TAIL; ECTODOMAIN SHEDDING; ENDOSOMES; FUNCTIONAL DOMAINS; HEK293 CELLS; HUMAN BRAIN; IMMUNOPRECIPITATES; IN-VITRO; IN-VIVO; LC-MS/MS; LIPOPROTEIN RECEPTORS; LOW DENSITY LIPOPROTEINS; PRECURSOR PROTEINS; PROTEIN KINASE; PROTEIN LEVEL; SITE DIRECTED MUTAGENESIS; TANDEM MASS SPECTROMETRY; TRANS-GOLGI NETWORK;

AMINO ACIDS; BRAIN; CELL MEMBRANES; ENZYME ACTIVITY; ENZYMES; GLYCOPROTEINS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

PHOSPHORYLATION;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; LIPOPROTEIN RECEPTOR; LIPOPROTEIN RECEPTOR 11; RHO KINASE; RHO KINASE II; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN TISSUE; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; BRAIN; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; LDL-RECEPTOR RELATED PROTEINS; MEMBRANE TRANSPORT PROTEINS; PHOSPHORYLATION; PROTEIN BINDING; RHO-ASSOCIATED KINASES;

EID: 79953221858     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.167239     Document Type: Article

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