Myocardial regeneration: The role of progenitor cells derived from bone marrow and heart

Progress in Molecular Biology and Translational Science

Volumn 111, Issue , 2012, Pages 195-215

  Wang, Xiaohong ^a   From, Arthur H L ^a   Zhang, Jianyi ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

bone marrow; heart failure; infarct; myocyte regeneration; stem cell

Indexed keywords

EID: 84865334323     PISSN: 18771173     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-398459-3.00009-5     Document Type: Chapter

References (61)

1. K.D. Poss, L.G. Wilson, and M.T. Keating Heart regeneration in zebrafish Science 298 2002 2188 2190 (Pubitemid 35471243)
2. B.N. Singh, N. Koyano-Nakagawa, J.P. Garry, and C.V. Weaver Heart of newt: a recipe for regeneration J Cardiovasc Transl Res 3 2010 397 409
3. E.R. Porrello, A.I. Mahmoud, E. Simpson, J.A. Hill, J.A. Richardson, and E.N. Olson Transient regenerative potential of the neonatal mouse heart Science 331 2011 1078 1080
4. A. Leri, J. Kajstura, P. Anversa, and W.H. Frishman Myocardial regeneration and stem cell repair Curr Probl Cardiol 33 2008 91 153 (Pubitemid 351163350)
5. A. Linke, P. Muller, D. Nurzynska, C. Casarsa, D. Torella, and A. Nascimbene Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function Proc Natl Acad Sci USA 102 2005 8966 8971 (Pubitemid 40881062)
6. D. Torella, M. Rota, D. Nurzynska, E. Musso, A. Monsen, and I. Shiraishi Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression Circ Res 94 2004 514 524 (Pubitemid 38326287)
7. K. Urbanek, D. Torella, F. Sheikh, A. De Angelis, D. Nurzynska, and F. Silvestri Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure Proc Natl Acad Sci USA 102 2005 8692 8697 (Pubitemid 40862797)
8. M.R. Afzal, H. Haider, N.M. Idris, S. Jiang, R.P. Ahmed, and M. Ashraf Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling Antioxid Redox Signal 12 2010 693 702
9. M. Kudo, Y. Wang, M.A. Wani, M. Xu, A. Ayub, and M. Ashraf Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart J Mol Cell Cardiol 35 2003 1113 1119 (Pubitemid 37083255)
10. Z. Pasha, Y. Wang, R. Sheikh, D. Zhang, T. Zhao, and M. Ashraf Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium Cardiovasc Res 77 2008 134 142 (Pubitemid 351195153)
11. A.R. Williams, and J.M. Hare Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease Circ Res 109 2011 923 940
12. R. Barazzoni, M. Zanetti, M. Sturnega, M. Stebel, A. Semolic, and A. Pirulli Insulin downregulates SIRT1 and AMPK activation and is associated with changes in liver fat, but not in inflammation and mitochondrial oxidative capacity, in streptozotocin-diabetic rat Clin Nutr 30 2011 384 390
13. K. Bersell, S. Arab, B. Haring, and B. Kuhn Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury Cell 138 2009 257 270
14. T. Braun, and S. Dimmeler Breaking the silence: stimulating proliferation of adult cardiomyocytes Dev Cell 17 2009 151 153
15. D.M. Breen, and A. Giacca Effects of insulin on the vasculature Curr Vasc Pharmacol 9 2011 321 332
16. V.M. Campa, R. Gutierrez-Lanza, F. Cerignoli, R. Diaz-Trelles, B. Nelson, and T. Tsuji Notch activates cell cycle reentry and progression in quiescent cardiomyocytes J Cell Biol 183 2008 129 141
17. V. Di Stefano, M. Giacca, M.C. Capogrossi, M. Crescenzi, and F. Martelli Knockdown of cyclin-dependent kinase inhibitors induces cardiomyocyte re-entry in the cell cycle J Biol Chem 286 2011 8644 8654
18. C. Bearzi, M. Rota, T. Hosoda, J. Tillmanns, A. Nascimbene, and A. De Angelis Human cardiac stem cells Proc Natl Acad Sci USA 104 2007 14068 14073 (Pubitemid 350003336)
19. O. Bergmann, R.D. Bhardwaj, S. Bernard, S. Zdunek, F. Barnabe-Heider, and S. Walsh Evidence for cardiomyocyte renewal in humans Science 324 2009 98 102
20. J. Kajstura, K. Urbanek, S. Perl, T. Hosoda, H. Zheng, and B. Ogorek Cardiomyogenesis in the adult human heart Circ Res 107 2010 305 315
21. J. Kajstura, K. Urbanek, M. Rota, C. Bearzi, T. Hosoda, and R. Bolli Cardiac stem cells and myocardial disease J Mol Cell Cardiol 45 2008 505 513
22. K.L. Laugwitz, A. Moretti, J. Lam, P. Gruber, Y. Chen, and S. Woodard Postnatal isl1 + cardioblasts enter fully differentiated cardiomyocyte lineages Nature 433 2005 647 653 (Pubitemid 40282999)
23. E. Messina, L. De Angelis, G. Frati, S. Morrone, S. Chimenti, and F. Fiordaliso Isolation and expansion of adult cardiac stem cells from human and murine heart Circ Res 95 2004 911 921 (Pubitemid 39435006)
24. R.R. Smith, L. Barile, H.C. Cho, M.K. Leppo, J.M. Hare, and E. Messina Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens Circulation 115 2007 896 908 (Pubitemid 46294730)
25. P.C. Hsieh, V.F. Segers, M.E. Davis, C. MacGillivray, J. Gannon, and J.D. Molkentin Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury Nat Med 13 2007 970 974 (Pubitemid 47222045)
26. X. Wang, Q. Hu, Y. Nakamura, J. Lee, G. Zhang, and A.H. From The role of the sca-1 +/CD31- cardiac progenitor cell population in postinfarction left ventricular remodeling Stem Cells 24 2006 1779 1788 (Pubitemid 44474191)
27. H. Kubo, N. Jaleel, A. Kumarapeli, R.M. Berretta, G. Bratinov, and X. Shan Increased cardiac myocyte progenitors in failing human hearts Circulation 118 2008 649 657
28. K. Urbanek, F. Quaini, G. Tasca, D. Torella, C. Castaldo, and B. Nadal-Ginard Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy Proc Natl Acad Sci USA 100 2003 10440 10445 (Pubitemid 37071897)
29. X. Wang, Q. Li, E. Braunlin, A.H. From, and J. Zhang The beneficial role of endogenous Sca-1 +/CD31- cells in post-infarction left ventricular remodeling Circulation 120 2009 S790
30. N. Rosenblatt-Velin, S. Ogay, A. Felley, W.L. Stanford, and T. Pedrazzini Cardiac dysfunction and impaired compensatory response to pressure overload in mice deficient in stem cell antigen-1 FASEB J 26 2012 229 239
31. Y. Iso, J.L. Spees, C. Serrano, B. Bakondi, R. Pochampally, and Y.H. Song Multipotent human stromal cells improve cardiac function after myocardial infarction in mice without long-term engraftment Biochem Biophys Res Commun 354 2007 700 706 (Pubitemid 46186241)
32. N. Noiseux, M. Gnecchi, M. Lopez-Ilasaca, L. Zhang, S.D. Solomon, and A. Deb Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation Mol Ther 14 2006 840 850 (Pubitemid 44752717)
33. L. Zeng, Q. Hu, X. Wang, A. Mansoor, J. Lee, and J. Feygin Bioenergetic and functional consequences of bone marrow-derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling Circulation 115 2007 1866 1875 (Pubitemid 46598900)
34. M. Gnecchi, H. He, O.D. Liang, L.G. Melo, F. Morello, and H. Mu Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells Nat Med 11 2005 367 368 (Pubitemid 40562318)
35. M. Gnecchi, H. He, N. Noiseux, O.D. Liang, L. Zhang, and F. Morello Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement FASEB J 20 2006 661 669 (Pubitemid 44933310)
36. X. Wang, M.N. Jameel, Q. Li, A. Mansoor, X. Qiang, and C. Swingen Stem cells for myocardial repair with use of a transarterial catheter Circulation 120 2009 S238 S246
37. A.A. Mangi, N. Noiseux, D. Kong, H. He, M. Rezvani, and J.S. Ingwall Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts Nat Med 9 2003 1195 1201 (Pubitemid 37173705)
38. G. Zhang, Y. Nakamura, X. Wang, Q. Hu, L.J. Suggs, and J. Zhang Controlled release of stromal cell-derived factor-1 alpha in situ increases c-kit + cell homing to the infarcted heart Tissue Eng 13 2007 2063 2071 (Pubitemid 47294002)
39. Y. Nakamura, X. Wang, C. Xu, A. Asakura, M. Yoshiyama, and A.H. From Xenotransplantation of long-term-cultured swine bone marrow-derived mesenchymal stem cells Stem Cells 25 2007 612 620 (Pubitemid 46354219)
40. H.C. Quevedo, K.E. Hatzistergos, B.N. Oskouei, G.S. Feigenbaum, J.E. Rodriguez, and D. Valdes Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity Proc Natl Acad Sci USA 106 2009 14022 14027
41. K.H. Schuleri, L.C. Amado, A.J. Boyle, M. Centola, A.P. Saliaris, and M.R. Gutman Early improvement in cardiac tissue perfusion due to mesenchymal stem cells Am J Physiol Heart Circ Physiol 294 2008 H2002 H2011
42. K.H. Schuleri, G.S. Feigenbaum, M. Centola, E.S. Weiss, J.M. Zimmet, and J. Turney Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy Eur Heart J 30 2009 2722 2732
43. J. Shujia, H.K. Haider, N.M. Idris, G. Lu, and M. Ashraf Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair Cardiovasc Res 77 2008 525 533 (Pubitemid 351197668)
44. M. Xu, R. Uemura, Y. Dai, Y. Wang, Z. Pasha, and M. Ashraf In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function J Mol Cell Cardiol 42 2007 441 448 (Pubitemid 46135600)
45. J.M. Hare, J.H. Traverse, T.D. Henry, N. Dib, R.K. Strumpf, and S.P. Schulman A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction J Am Coll Cardiol 54 2009 2277 2286
46. A.R. Williams, B. Trachtenberg, D.L. Velazquez, I. McNiece, P. Altman, and D. Rouy Intramyocardial stem cell injection in patients with ischemic cardiomyopathy: functional recovery and reverse remodeling Circ Res 108 2011 792 796
47. M.N. Jameel, Q. Li, A. Mansoor, X. Qiang, A. Sarver, and X. Wang Long term functional improvement and gene expression changes after bone marrow derived multipotent progenitor cell transplantation in myocardial infarction Am J Physiol Heart Circ Physiol 298 2010 H1348 H1356
48. J. Liu, Q. Hu, Z. Wang, C. Xu, X. Wang, and G. Gong Autologous stem cell transplantation for myocardial repair Am J Physiol Heart Circ Physiol 287 2004 H501 H511 (Pubitemid 38960792)
49. G. Suzuki, V. Iyer, T.C. Lee, and J.M. Canty Jr. Autologous mesenchymal stem cells mobilize cKit + and CD133 + bone marrow progenitor cells and improve regional function in hibernating myocardium Circ Res 109 2011 1044 1054
50. M.I. Niagara, H. Haider, S. Jiang, and M. Ashraf Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart Circ Res 100 2007 545 555 (Pubitemid 46673264)
51. Y. Suzuki, H.W. Kim, M. Ashraf, and H. Haider Diazoxide potentiates mesenchymal stem cell survival via NF-kappaB-dependent miR-146a expression by targeting Fas Am J Physiol Heart Circ Physiol 299 2010 H1077 H1082
52. R. Bolli, A.R. Chugh, D. D'Amario, J.H. Loughran, M.F. Stoddard, and S. Ikram Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial Lancet 378 2011 1847 1857
53. M.E. Padin-Iruegas, Y. Misao, M.E. Davis, V.F. Segers, G. Esposito, and T. Tokunou Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction Circulation 120 2009 876 887
54. M. Rota, M.E. Padin-Iruegas, Y. Misao, A. De Angelis, S. Maestroni, and J. Ferreira-Martins Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function Circ Res 103 2008 107 116
55. X.L. Tang, G. Rokosh, S.K. Sanganalmath, F. Yuan, H. Sato, and J. Mu Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction Circulation 121 2010 293 305
56. P.V. Johnston, T. Sasano, K. Mills, R. Evers, S.T. Lee, and R.R. Smith Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy Circulation 120 2009 1075 1083 1077 p following 1083
57. I. Chimenti, R.R. Smith, T.S. Li, G. Gerstenblith, E. Messina, and A. Giacomello Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice Circ Res 106 2010 971 980
58. S.T. Lee, A.J. White, S. Matsushita, K. Malliaras, C. Steenbergen, and Y. Zhang Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction J Am Coll Cardiol 57 2011 455 465
59. F.S. Loffredo, M.L. Steinhauser, J. Gannon, and R.T. Lee Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair Cell Stem Cell 8 2011 389 398
60. K. Malliaras, and E. Marban Cardiac cell therapy: where we've been, where we are, and where we should be headed Br Med Bull 98 2011 161 185
61. Y. Zhang, T.S. Li, S.T. Lee, K.A. Wawrowsky, K. Cheng, and G. Galang Dedifferentiation and proliferation of mammalian cardiomyocytes PLoS One 5 2010 e12559