Adiponectin concentration in plasma is associated with muscle fiber size in healthy middle-aged men

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 72, Issue 5, 2012, Pages 395-402

  Pisto, Pauliina ^a   Santaniemi, Merja ^a   Turpeinen, Juha Pekka ^a   Ukkola, Olavi ^a   Kesäniemi, Y Antero ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

Adipokines; Ectopic fat; Metabolic syndrome; Overweight; Skeletal muscle

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; C REACTIVE PROTEIN; LEPTIN;

ADULT; AGE; ARTICLE; BODY MASS; CELL SIZE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; HUMAN; MALE; METABOLIC SYNDROME X; MUSCLE BIOPSY; MUSCLE CELL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; ORAL GLUCOSE TOLERANCE TEST; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; VASTUS LATERALIS MUSCLE;

ADIPONECTIN; ADIPOSITY; BODY MASS INDEX; C-REACTIVE PROTEIN; CELL SIZE; CROSS-SECTIONAL STUDIES; GHRELIN; HEALTH; HUMANS; LEPTIN; MALE; MIDDLE AGED; MUSCLE FIBERS, SKELETAL; QUADRICEPS MUSCLE; RECEPTORS, ADIPONECTIN; RESISTIN;

EID: 84865324576     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.3109/00365513.2012.687759     Document Type: Article

References (49)

1. Kelley DE, G oodpaster BH, S torlien L. M uscle triglyceride and insulin resistance. Annu Rev Nutr 2002 ; 22 : 325-46 . (Pubitemid 35221465)
2. Abdul-Ghani MA, D eFronzo RA. P athogenesis of insulin resistance in skeletal muscle. J Biomed Biotechnol 2010 ; 47 : 62-79 .
3. Kokta TA, D odson M V, G ertler A, H ill R A. I ntercellular signaling between adipose tissue and muscle tissue. Domest Anim Endocrinol 2004 ; 27 : 303-31 . (Pubitemid 39415823)
4. Malenfant P, J oanisse DR, T heriault R, G oodpaster BH, Kelley DE, Simoneau JA. Fat content in individual muscle fibers of lean and obese subjects. Int J Obes Relat Metab Disord 2001 ; 25 : 1316-21 . (Pubitemid 32835448)
5. Scott W, S tevens J, B inder-Macleod SA. H uman skeletal muscle fiber type classifi cations. Phys Ther 2001 ; 81 : 1810-6 . (Pubitemid 33027477)
6. Zierath J R, H awley J A. S keletal muscle fiber type: infl uence on contractile and metabolic properties. Plos Biol 2004 ; 2 : e348 .
7. Lillioja S, Y oung AA, C ulter CL, I vy JL, A bbott W G, Zawadzki JK, Yki-Jarvinen H, Christin L, Secomb TW, Bogardus C. Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. J Clin Invest 1987 ; 80 : 415-24 .
8. Tanner CJ, B arakat HA, D ohm GL, P ories WJ, M acDonald KG, Cunningham PR, Swanson MS, Houmard JA. Muscle fiber type is associated with obesity and weight loss. Am J Physiol Endocrinol Metab 2002 ; 282 : E1191-6 . (Pubitemid 34654686)
9. Gerrits MF, G hosh S, K avaslar N, H ill B, T our A, S eifert EL, Beauchamp B, Gorman S, Stuart J, Dent R, McPherson R, Harper ME. Distinct skeletal muscle fiber characteristics and gene expression in diet-sensitive versus diet-resistant obesity. J Lipid Res 2010 ; 51 : 2394-404 .
10. Tsochatzis EA, P apatheodoridis GV, A rchimandritis AJ. A dipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy. Mediators Inflamm 2009 ; 831670-8 .
11. Delaigle AM, J onas JC, B auche IB, C ornu O, B richard SM. Induction of adiponectin in skeletal muscle by Inflammatory cytokines: in vivo and in vitro studies. Endocrinology 2004 ; 145 : 5589-97 . (Pubitemid 39564599)
12. Godoy-Matos A F, B ahia LR, D omingues RC, S icuro F, Tambascia M, Geloneze B, Kraemer-Aguiar LG, Bouskela E. Adiponectin is related to intramyocellular lipid content in non-diabetic adults. J Endocrinol Invest 2010 ; 33 : 382-7 .
13. Kantartzis K, S taiger H, M achann J, S chick F, C laussen CD, Machicao F, Fritsche A, Haring HU, Stefan N. Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans. Obesity 2009 ; 17 : 390-2 .
14. Ingelsson E, A rnlov J, Z ethelius B, V asan RS, F lyvbjerg A, Frystyk J, Berne C, Hanni A, Lind L, Sundstrom J. Associations of serum adiponectin with skeletal muscle morphology and insulin sensitivity. J Clin Endocrinol Metab 2009 ; 94 : 953-7 .
15. Gnacinska M, M algorzewicz S, S tojek M, L ysiak-Szydlowska W, Sworczak K. Role of adipokines in complications related to obesity: a review. Adv Med Sci 2009 ; 54 : 150-7 .
16. Stofkova A. R esistin and visfatin: regulators of insulin sensitivity, inflammation and immunity. Endocr Regul 2010 ; 44 : 25-36 .
17. Meier U, G ressner AM. E ndocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clin Chem 2004 ; 50 : 1511-25 . (Pubitemid 39121218)
18. Poykko S M, K ellokoski E, H orkko S, K auma H, K esaniemi YA, Ukkola O. Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes. Diabetes 2003 ; 52 : 2546-53 . (Pubitemid 37210544)
19. Brooks GC, B laha MJ, B lumenthal RS. R elation of C-reactive protein to abdominal adiposity. Am J Cardiol 2010 ; 106 : 56-61 .
20. Kadowaki T, Y amauchi T, K ubota N, H ara K, U eki K, T obe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006 ; 116 : 1784-92 . (Pubitemid 44033298)
21. Bredella M A, T orriani M, G homi R H, T homas B J, B rick D J, Gerweck AV, Harrington LM, Miller KK. Adiponectin is inversely associated with intramyocellular and intrahepatic lipids in obese premenopausal women. Obesity 2011 ; 19 : 911-6 .
22. Iwabu M, Y amauchi T, O kada-Iwabu M, S ato K, N akagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T. Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2 + ) and AMPK/SIRT1. Nature 2010 ; 464 : 1313-9 .
23. Turpeinen J P, L eppavuori J, H einonen O J, K aila K, S alo J, Lilja M, Kesaniemi YA. Muscle fiber type I infl uences lipid oxidation during low-intensity exercise in moderately active middle-aged men. Scand J Med Sci Sports 2006 ; 16 : 134-40 . (Pubitemid 43388377)
24. Ukkola O, P oykko S, P aivansalo M, K esaniemi YA. I nteractions between ghrelin, leptin and IGF-I affect metabolic syndrome and early atherosclerosis. Ann Med 2008 ; 40 : 465-73 .
25. Rantala AO, K auma H, L ilja M, S avolainen MJ, R eunanen A, Kesaniemi YA. Prevalence of the metabolic syndrome in drug-treated hypertensive patients and control subjects. J Intern Med 1999 ; 245 : 163-74 . (Pubitemid 29089113)
26. Durnin JV, W omersley J. B ody fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974 ; 32 : 77-97 .
27. Santaniemi M, K esaniemi YA, U kkola O. L ow plasma adiponectin concentration is an indicator of the metabolic syndrome. Eur J Endocrinol 2006 ; 155 : 745-50 . (Pubitemid 44857499)
28. Pisto P, Ukkola O, Santaniemi M, Kesaniemi Y A. Plasma adiponectin-an independent indicator of liver fat accumulation. Metabolism 2011 ; 60:1515-20 .
29. Ukkola O, Paivansalo M, Kesaniemi Y A. High plasma resistin level is associated with enhanced highly sensitive C-reactive protein and leukocytes. J Clin Endocrinol Metab 2006 ; 91 : 2755-60 . (Pubitemid 44024647)
30. Katz A, N ambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000 ; 85 : 2402-10 . (Pubitemid 32269192)
31. Dubowitz V, B rooke M, N eville H. M uscle biopsy: a modern approach. London: Saunders WB Co ., 1973 .
32. Janssen I, H eymsfi eld SB, W ang ZM, R oss R. S keletal muscle mass and distribution in 468 men and women aged 18-88 yr. J Appl Physiol 2000 ; 89 : 81-8 . (Pubitemid 30482566)
33. Stefanyk L E, D yck D J. The interaction between adipokines, diet and exercise on muscle insulin sensitivity. Curr Opin Clin Nutr Metab Care 2010 ; 13 : 255-9 .
34. Gustafson B. A dipose tissue, inflammation and atherosclerosis. J Ateroscler Thromb 2010 ; 17 : 332-41 .
35. Gavin T P, S tallings HW, 3rd, Zwetsloot KA, W esterkamp LM, Ryan NA, Moore RA, Pofahl WE, Hickner RC. Lower capillary density but no difference in VEGF expression in obese vs. lean young skeletal muscle in humans. J Appl Physiol 2005 ; 98 : 315-21 . (Pubitemid 40041262)
36. Thompson LV. E ffects of age and training on skeletal muscle physiology and performance. Phys Ther 1994 ; 74 : 71-81 . (Pubitemid 24020897)
37. Nawrocki A R, S cherer P E. The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation. Curr Opin Paharmacol 2004 ; 4 : 281-9 . (Pubitemid 38585314)
38. Civitarese AE, U kropcova B, C arling S, H ulver M, D eFronzo RA, Mandarino L, Ravussin E, Smith SR. Role of adiponectin in human skeletal muscle bioenergetics. Cell Metab 2006 ; 4 : 75-87 . (Pubitemid 43942255)
39. Perseghin G, L attuada G, D e Cobelli F, E sposito A, B elloni E, Canu T, Ragogna F, Scifo P, Del Maschio A, Luzi L. Serum retinol-binding protein-4, leptin, and adiponectin concentrations are related to ectopic fat accumulation. J Clin Endocrinol Metab 2007 ; 92 : 4883-8 . (Pubitemid 350223473)
40. Civitarese AE, J enkinson C P, R ichardson D, B ajaj M, C usi K, Kashyap S, Berria R, Belfort R, DeFronzo RA, Mandarino LJ, Ravussin E. Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes. Diabetologia 2004 ; 47 : 816-20 . (Pubitemid 38756993)
41. Tsuchida A, Y amauchi T, I to Y, H ada Y, M aki T, T akekawa S, Kamon J, Kobayashi M, Suzuki R, Hara K, Kubota N, Terauchi Y, Froguel P, Nakae J, Kasuga M, Accili D, Tobe K, Ueki K, Nagai R, Kadowaki T. Insulin/Foxo1 pathway regulates expression levels of adiponectin receptors and adiponectin sensitivity. J Biol Chem 2004 ; 279 : 30817-22 . (Pubitemid 38938015)
42. Lara-Castro C, G arvey W T. I ntracellular lipid accumulation in liver and muscle and the insulin resistance syndrome. Endocrinol Metab Clin North Am 2008 ; 37 : 841-56 .
43. Yang WS, L ee WJ, F unahashi T, T anaka S, M atsuzawa Y, Chao CL, Chen CL, Tai TY, Chuang LM. Weight reduction increases plasma levels of an adipose-derived anti-Inflammatory protein, adiponectin. J Clin Endocrinol Metab 2001 ; 86 : 3815-9 . (Pubitemid 32755982)
44. Arawaka N, D aimon M, O izumi T, J imbu Y, K ameda W, Yamaguchi H, Ohnuma H, Tominaga M, Kato T. Correlation between change in body weight rather than current body weight and change in serum adiponectin levels in a Japanese population-the Funagata study. Metabolism 2006 ; 55 : 324-30 . (Pubitemid 43234385)
45. Bennett N R, B oyne M S, C ooper R S, R oyal-Thomas TY, Bennett FI, Luke A, Wilks RJ, Forrester TE. Impact of adiponectin and ghrelin on incident glucose intolerance and on weight change. Clin Endocrinol (Oxf) 2009 ; 70 : 408-14 .
46. Reinehr T, R oth CL. A new link between skeleton, obesity and insulin resistance: relationships between osteocalcin, leptin and insulin resistance in obese children before and after weight loss. Int J Obes (Lond) 2010 ; 34 : 852-8 .
47. Malenfant P, T remblay A, D oucet E, I mbeault P, S imoneau JA, Joanisse DR. Elevated intramyocellular lipid concentration in obese subjects is not reduced after diet and exercise training. Am J Physiol Endocrinol Metab 2001 ; 280 : E632-9 .
48. van Herpen N A, S chrauwen-Hinderling V B, S chaart G, Mensink RP, Schrauwen P. Three weeks on a high-fat diet increases intrahepatic lipid accumulation and decreases metabolic fl exibility in healthy overweight men. J Clin Endocrinol Metab 2011 ; 96 : 691-5 .
49. Cnop M, H avel P J, U tzschneider K M, C arr D B, S inha M K, Boyko EJ, Retzlaff BM, Knopp RH, Brunzell JD, Kahn SE. Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia 2003 ; 46 : 459-69. (Pubitemid 36577787)