Lipase-catalyzed remote kinetic resolution of citalopram intermediate by asymmetric alcoholysis and thermodynamic analysis

Bioprocess and Biosystems Engineering

Volumn 35, Issue 6, 2012, Pages 1043-1048

  Wang, Shi Zhen ^a,b   Wu, Jian Ping ^b   Xu, Gang ^b   Yang, Li Rong ^b  

^a Key Laboratory for Chemical Biology of Fujian Province   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Asymmetric alcoholysis; Chiral tertiary alcohol; Citalopram; Remote resolution; Thermodynamic analysis

Indexed keywords

ACTIVATION ENTHALPIES; ACTIVATION ENTROPIES; ACTIVATION FREE ENERGY; ACYL ACCEPTOR; ALCOHOLYSIS; CHIRAL DISCRIMINATION; CHIRAL TERTIARY ALCOHOLS; CITALOPRAM; ENANTIOMER DISCRIMINATION; KINETIC RESOLUTION; LIPASE-CATALYZED; NOVOZYM435; TERTIARY ALCOHOLS; THERMO DYNAMIC ANALYSIS;

CATALYSIS; CHIRALITY; ENANTIOMERS; ENANTIOSELECTIVITY; ORGANIC SOLVENTS; REACTION RATES; THERMOANALYSIS;

THERMODYNAMIC PROPERTIES;

CITALOPRAM; ORGANIC SOLVENT; TRIACYLGLYCEROL LIPASE;

ALCOHOLYSIS; ARTICLE; BIOTECHNOLOGICAL PROCEDURES; CANDIDA ANTARCTICA; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHROMATOGRAPHY; ENANTIOSELECTIVITY; ENTHALPY; ENTROPY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

CITALOPRAM; KINETICS; LIPASE; MODELS, CHEMICAL; THERMODYNAMICS;

EID: 84865320019     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-012-0690-8     Document Type: Article

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