Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine

Journal of Inorganic Biochemistry

Volumn 115, Issue , 2012, Pages 100-105

  Łakomska, Iwona ^a   Fandzloch, Marzena ^a   Muzioł, Tadeusz ^a   Sitkowski, Jerzy ^b   Wietrzyk, Joanna ^c  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b National Institute of Medicines   (Poland)

^c INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

Author keywords

15N NMR; In vitro cytotoxicity; Platinum(II) complex; Triazolopyrimidine; X ray

Indexed keywords

LIGAND; PLATINUM DERIVATIVE; PYRIMIDINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER; CARBON NUCLEAR MAGNETIC RESONANCE; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; LUNG NON SMALL CELL CANCER; NITROGEN NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; X RAY DIFFRACTION;

BREAST NEOPLASMS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOTOXINS; FEMALE; HUMANS; LUNG NEOPLASMS; PLATINUM; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

EID: 84865311020     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2012.05.005     Document Type: Article

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