Long-chain acylcarnitines regulate the herg channel

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Ferro, Fabio ^a   Ouillé, Aude ^b   Tran, Truong An ^a   Fontanaud, Pierre ^c   Bois, Patrick ^d   Babuty, Dominique ^e   Labarthe, François ^a   Le Guennec, Jean Yves ^b  

^a UNIVERSITÉ DE TOURS   (France)

^b UNIVERSITY OF MONTPELLIER   (France)

^c INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^d UNIVERSITÉ DE POITIERS   (France)

^e SERVICE DE DERMATOLOGIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; CALCIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; LONG CHAIN ACYLCARNITINE DERIVATIVE; OLEIC ACID; OLEIC ACID ACYLCARNITINE; PALMITIC ACID METHYL ESTER; PALMITOYLCARNITINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNE1; POTASSIUM CHANNEL KV7.1; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ACTION POTENTIAL DURATION; ARTICLE; BIOACCUMULATION; CELL KINETICS; CELL STIMULATION; CELL STRAIN HEK293; COMPUTER SIMULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEACTIVATION KINETICS; DISEASE ASSOCIATION; ELECTRICAL POTENTIAL PARAMETERS; EXTRACELLULAR SPACE; FATTY ACID METABOLISM; HEART ARRHYTHMIA; HEART ELECTROPHYSIOLOGY; INTRACELLULAR SPACE; MATHEMATICAL MODEL; PATCH CLAMP; REGULATORY MECHANISM;

CARNITINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGICAL PROCESSES; ETHER-A-GO-GO POTASSIUM CHANNELS; EXTRACELLULAR SPACE; HEK293 CELLS; HUMANS; INTRACELLULAR SPACE;

EID: 84865295075     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041686     Document Type: Article

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