TGFβ inhibition during expansion phase increases the chondrogenic re-differentiation capacity of human articular chondrocytes

Osteoarthritis and Cartilage

Volumn 20, Issue 10, 2012, Pages 1152-1160

  Narcisi, R ^a,b   Signorile, L ^a   Verhaar, J A N ^a   Giannoni, P ^b   van Osch, G J V M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Advanced Biotechnology Center   (Italy)

Author keywords

Chondrocyte; Chondrogenesis; Expansion culture; Hypertrophy; Proliferation; TGF

Indexed keywords

ALPHA TUBULIN; COLLAGEN TYPE 10; COLLAGENASE 3; MESSENGER RNA; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL EXPANSION; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FETAL CALF SERUM; GENE EXPRESSION; HISTOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; PHENOTYPE; PRIORITY JOURNAL; WESTERN BLOTTING;

ANTIBODIES, BLOCKING; BENZAMIDES; BIOLOGICAL MARKERS; CARTILAGE, ARTICULAR; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; CULTURE MEDIA; CULTURE MEDIA, SERUM-FREE; HUMANS; HYPERTROPHY; KNEE INJURIES; OSTEOARTHRITIS, KNEE; PYRAZOLES; PYRIMIDINES; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84865289572     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2012.06.010     Document Type: Article

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