Role of tumor necrosis factor-α in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion

Critical Care Medicine

Volumn 34, Issue 2, 2006, Pages 484-491

  Lu, Xiangru ^a   Hamilton, Joel A ^a,b   Shen, Ji ^a,b   Pang, Theresa ^a,b   Jones, Douglas L ^b   Potter, Richard F ^a,b   Arnold, J Malcolm O ^b   Feng, Qingping ^a,b,c  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

Cardiac dysfunction; Hindlimb ischemia and reperfusion; Myocardial apoptosis; Systemic inflammatory response syndrome; Tumor necrosis factor

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; ETANERCEPT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL OCCLUSION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART DISEASE; HEART FUNCTION; HINDLIMB; LIMB ISCHEMIA; MALE; MOUSE; MYOCARDIAL DISEASE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; REPERFUSION INJURY; STATISTICAL SIGNIFICANCE; WILD TYPE;

EID: 31344463424     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000199079.64231.C1     Document Type: Article

References (37)

1. Davies MG, Hagen PO: Systemic inflammatory response syndrome. Br J Surg 1997; 84:920-935
2. Beal AL, Cerra FB: Multiple organ failure syndrome in the 1990s: Systemic inflammatory response and organ dysfunction. JAMA 1994; 271:226-233
3. Froon AH, Greve JW, Van der Linden CJ, et al: Increased concentrations of cytokines and adhesion molecules in patients after repair of abdominal aortic aneurysm. Eur J Surg 1996; 162:287-296
4. Holzheimer RG, Gross J, Schein M: Pro- and anti-inflammatory cytokine-response in abdominal aortic aneurysm repair: A clinical model of ischemia-reperfusion. Shock 1999; 11:305-310
5. Juvonen J, Surcel HM, Satta J, et al: Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol 1997; 17:2843-2847
6. Swartbol P, Norgren L, Parsson H, et al: Endovascular abdominal aortic aneurysm repair induces significant alterations in surface adhesion molecule expression on donor white blood cells exposed to patient plasma. Eur J Vasc Endovasc Surg 1997; 14:48-59
7. Goldman L: Cardiac risk for vascular surgery. J Am Coll Cardiol 1996; 27:799-802
8. Baron JF, Mundler O, Bertrand M, et al: Dipyridamole-thallium scintigraphy and gated radionuclide angiography to assess cardiac risk before abdominal aortic surgery. N Engl J Med 1994; 330:663-669
9. Kumar A, Haery C, Parrillo JE: Myocardial dysfunction in septic shock. Crit Care Clin 2000; 16:251-287
10. Shahani R, Marshall JG, Rubin BB, et al: Role of TNF-alpha in myocardial dysfunction after hemorrhagic shock and lower-torso ischemia. Am J Physiol Heart Circ Physiol 2000; 278:H942-H950
11. Seekamp A, Warren JS, Remick DG, et al: Requirements for tumor necrosis factor-alpha and interleukin-1 in limb ischemia/reperfusion injury and associated lung injury. Am J Pathol 1993; 143:453-463
12. White DJ, Maass DL, Sanders B, et al: Cardiomyocyte intracellular calcium and cardiac dysfunction after burn trauma. Crit Care Med 2002; 30:14-22
13. Gurevitch J, Frolkis I, Yuhas Y, et al: Tumor necrosis factor-alpha is released from the isolated heart undergoing ischemia and reperfusion. J Am Coll Cardiol 1996; 28:247-252
14. Kapadia S, Lee J, Torre-Amione G, et al: Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration. J Clin Invest 1995; 96:1042-1052
15. Meldrum DR, Cleveland JC Jr, Cain BS, et al: Increased myocardial tumor necrosis factor-alpha in a crystalloid-perfused model of cardiac ischemia-reperfusion injury. Ann Thorac Surg 1998; 65:439-443
16. Kelly RA, Smith TW: Cytokines and cardiac contractile function. Circulation 1997; 95:778-781
17. Meldrum DR: Tumor necrosis factor in the heart. Am J Physiol 1998; 274:R577-R595
18. Yokoyama T, Vaca L, Rossen RD, et al: Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart. J Clin Invest 1993; 92:2303-2312
19. Song W, Lu X, Feng Q: Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes. Cardiovasc Res 2000; 45:595-602
20. Krown KA, Page MT, Nguyen C, et al: Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death. J Clin Invest 1996; 98:2854-2865
21. Aikawa R, Nitta-Komatsubara Y, Kudoh S, et al: Reactive oxygen species induce cardiomyocyte apoptosis partly through TNF-alpha. Cytokine 2002; 18:179-183
22. Carlson DL, Willis MS, White DJ, et al: Tumor necrosis factor-alpha-induced caspase activation mediates endotoxin-related cardiac dysfunction. Crit Care Med 2005; 33:1021-1028
23. Brock RW, Lawlor DK, Harris KA, et al: Initiation of remote hepatic injury in the rat: Interactions between Kupffer cells, tumor necrosis factor-alpha, and microvascular perfusion. Hepatology 1999; 30:137-142
24. Peng T, Lu X, Lei M, et al: Inhibition of p38 MAPK decreases myocardial TNF-alpha expression and improves myocardial function and survival during acute endotoxemia in mice. Cardiovasc Res 2003; 59:893-900
25. phox-containing NADH oxidase in lipopolysaccharide-induced tumor necrosis factor-alpha expression and myocardial depression. Circulation 2005; 111:1637-1644
26. Feng Q, Song W, Lu X, et al: Development of heart failure and congenital septal defects in mice lacking endothelial nitric oxide synthase. Circulation 2002; 106:873-879
27. Moe GW, Naik G, Konig A, et al: Early and persistent activation of myocardial apoptosis, bax and caspases: Insights into mechanisms of progression of heart failure. Pathophysiology 2002; 8:183-192
28. Lazarus B, Messina A, Barker JE, et al: The role of mast cells in ischaemia-reperfusion injury in murine skeletal muscle. J Pathol 2000; 191:443-448
29. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-254
30. van der Velden J, Merkus D, Klarenbeek BR, et al: Alterations in myofilament function contribute to left ventricular dysfunction in pigs early after myocardial infarction. Circ Res 2004; 95:e85-e95
31. Feng Q, Lu X, Jones DL, et al: Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice. Circulation 2001; 104:700-704
32. Lawlor DK, Brock RW, Harris KA, et al: Cytokines contribute to early hepatic parenchymal injury and microvascular dysfunction after bilateral hindlimb ischemia. J Vasc Surg 1999; 30:533-541
33. Sternbergh WC III, Turttle TM, Makhoul RG, et al: Postischemic extremities exhibit immediate release of tumor necrosis factor. J Vasc Surg 1994; 20:474-481
34. Li JM, Fan LM, Christie MR, et al: Acute tumor necrosis factor alpha signaling via NADPH oxidase in microvascular endothelial cells: Role of p47phox phosphorylation and binding to TRAF4. Mol Cell Biol 2005; 25:2320-2330
35. Fauvel H, Marchetti P, Chopin C, et al: Differential effects of caspase inhibitors on endotoxin-induced myocardial dysfunction and heart apoptosis. Am J Physiol Heart Circ Physiol 2001; 280:H1608-H1614
36. Olivetti G, Abbi R, Quaini F, et al: Apoptosis in the failing human heart. N Engl J Med 1997; 336:1131-1141
37. Razavi HM, Hamilton JA, Feng Q: Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure. Pharmacol Ther 2005; 106:147-162