ERK1/2 activation is a therapeutic target in age-related macular degeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 34, 2012, Pages 13781-13786

  Dridi, Sami ^a   Hirano, Yoshio ^a   Tarallo, Valeria ^a   Kim, Younghee ^a   Fowler, Benjamin J ^a   Ambati, Balamurali K ^b,c   Bogdanovich, Sasha ^a   Chiodo, Vince A ^d   Hauswirth, William W ^d   Kugel, Jennifer F ^e   Goodrich, James A ^e   Ponicsan, Steven L ^e   Hinton, David R ^f   Kleinman, Mark E ^a   Baffi, Judit Z ^a   Gelfand, Bradley D ^a   Ambati, Jayakrishna ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cell death; Mobile elements; Retinal degeneration

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DICER; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; VINCULIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GEOGRAPHIC ATROPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; WILD TYPE;

ANIMALS; DEAD-BOX RNA HELICASES; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MACULAR DEGENERATION; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; RETINAL PIGMENT EPITHELIUM; RIBONUCLEASE III; SIGNAL TRANSDUCTION;

EID: 84865281483     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1206494109     Document Type: Article

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