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Volumn 36, Issue 5, 2012, Pages 596-602

Thermal injury activates the eEF2K-dependent eEF2 pathway in pediatric patients

Author keywords

burn; hypermeta bolism; muscle; protein synthesis; skin

Indexed keywords

ELONGATION FACTOR 2; ELONGATION FACTOR 2 KINASE; MUSCLE PROTEIN;

EID: 84865261119     PISSN: 01486071     EISSN: None     Source Type: Journal    
DOI: 10.1177/0148607111422234     Document Type: Article
Times cited : (5)

References (37)
  • 3
    • 34548049803 scopus 로고    scopus 로고
    • A model of myocardial inflammation and dysfunction in burn complicated by sepsis
    • DOI 10.1097/01.shk.0000238064.54332.c8, PII 0002438220070900000011
    • Horton JW. A model of myocardial inflammation and dysfunction in burn complicated by sepsis. Shock. 2007 ; 28: 326-333 (Pubitemid 47282024)
    • (2007) Shock , vol.28 , Issue.3 , pp. 326-333
    • Horton, J.W.1
  • 4
    • 18744394334 scopus 로고    scopus 로고
    • Mortality related to gender, age, sepsis, and ethnicity in severely burned children
    • DOI 10.1097/01.shk.0000163207.29655.90
    • Barrow RE, Przkora R, Hawkins HK, Barrow LN, Jeschke MG, Herndon DN. Mortality related to gender, age, sepsis, and ethnicity in severely burned children. Shock. 2005 ; 23: 485-487 (Pubitemid 40677418)
    • (2005) Shock , vol.23 , Issue.6 , pp. 485-487
    • Barrow, R.E.1    Przkora, R.2    Hawkins, H.K.3    Barrow, L.N.4    Jeschke, M.G.5    Herndon, D.N.6
  • 5
    • 0036516123 scopus 로고    scopus 로고
    • Modulating the hypermetabolic response to burn injuries
    • Williams GJ, Herndon DN. Modulating the hypermetabolic response to burn injuries. J Wound Care. 2002 ; 11: 87-89
    • (2002) J Wound Care , vol.11 , pp. 87-89
    • Williams, G.J.1    Herndon, D.N.2
  • 6
    • 0031768591 scopus 로고    scopus 로고
    • Treatment of burned rats with insulin-like growth factor i inhibits the catabolic response in skeletal muscle
    • Fang CH, Li BG, Wang JJ, Fischer JE, Hasselgren PO. Treatment of burned rats with insulin-like growth factor I inhibits the catabolic response in skeletal muscle. Am J Physiol. 1998 ; 275: R1091-1098
    • (1998) Am J Physiol , vol.275 , pp. 1091-1098
    • Fang, C.H.1    Li, B.G.2    Wang, J.J.3    Fischer, J.E.4    Hasselgren, P.O.5
  • 7
    • 7944236989 scopus 로고    scopus 로고
    • Leucine acutely reverses burn-induced alterations in translation initiation in heart
    • DOI 10.1097/01.shk.0000136096.03931.ed
    • Lang CH, Deshpande N, Frost RA. Leucine acutely reverses burn-induced alterations in translation initiation in heart. Shock. 2004 ; 22: 326-332 (Pubitemid 39468971)
    • (2004) Shock , vol.22 , Issue.4 , pp. 326-332
    • Lang, C.H.1    Deshpande, N.2    Frost, R.A.3
  • 8
    • 35848944101 scopus 로고    scopus 로고
    • Total aminoacyl-transfer RNA pool is greater in liver than muscle in rabbits
    • Wolfe RR, Song J, Sun J, Zhang XJ. Total aminoacyl-transfer RNA pool is greater in liver than muscle in rabbits. J Nutr. 2007 ; 137: 2333-2338 (Pubitemid 350058697)
    • (2007) Journal of Nutrition , vol.137 , Issue.11 , pp. 2333-2338
    • Wolfe, R.R.1    Song, J.2    Sun, J.3    Zhang, X.-J.4
  • 9
    • 1642284457 scopus 로고    scopus 로고
    • Thermal injury impairs cardiac protein synthesis and is associated with alterations in translation initiation
    • Lang CH, Frost RA, Vary TC. Thermal injury impairs cardiac protein synthesis and is associated with alterations in translation initiation. Am J Physiol Regul Integr Comp Physiol. 2004 ; 286: R740-750
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286 , pp. 740-750
    • Lang, C.H.1    Frost, R.A.2    Vary, T.C.3
  • 10
    • 0025254522 scopus 로고
    • Kinetic determination of the effects of ADP-ribosylation on the interaction of eukaryotic elongation factor 2 with ribosomes
    • Nygard O, Nilsson L. Kinetic determination of the effects of ADP-ribosylation on the interaction of eukaryotic elongation factor 2 with ribosomes. J Biol Chem. 1990 ; 265: 6030-6034
    • (1990) J Biol Chem , vol.265 , pp. 6030-6034
    • Nygard, O.1    Nilsson, L.2
  • 12
    • 23844457609 scopus 로고    scopus 로고
    • Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain
    • DOI 10.1111/j.1742-4658.2005.04833.x
    • Li X, Alafuzoff I, Soininen H, Winblad B, Pei JJ. Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain. FEBS J. 2005 ; 272: 4211-4220 (Pubitemid 41160927)
    • (2005) FEBS Journal , vol.272 , Issue.16 , pp. 4211-4220
    • Li, X.1    Alafuzoff, I.2    Soininen, H.3    Winblad, B.4    Pei, J.-J.5
  • 13
    • 0036290402 scopus 로고    scopus 로고
    • Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus
    • DOI 10.1016/S0006-291X(02)00324-8, PII S0006291X02003248
    • Arora S, Yang JM, Craft J, Hait W. Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus. Biochem Biophys Res Commun. 2002 ; 293: 1073-1076 (Pubitemid 34694151)
    • (2002) Biochemical and Biophysical Research Communications , vol.293 , Issue.3 , pp. 1073-1076
    • Arora, S.1    Yang, J.-M.2    Craft, J.3    Hait, W.4
  • 14
    • 70149091640 scopus 로고    scopus 로고
    • Calcium and ER stress mediate hepatic apoptosis after burn injury
    • Jeschke MG, Gauglitz GG, Song J, et al. Calcium and ER stress mediate hepatic apoptosis after burn injury. J Cell Mol Med. 2009 ; 13: 1857-1865
    • (2009) J Cell Mol Med , vol.13 , pp. 1857-1865
    • Jeschke, M.G.1    Gauglitz, G.G.2    Song, J.3
  • 15
    • 84857535742 scopus 로고    scopus 로고
    • Severe injury is associated with insulin resistance, ER stress response and unfolded protein response
    • Jeschke MG, Finnerty CC, Herndon DN, et al. Severe injury is associated with insulin resistance, ER stress response and unfolded protein response. Ann Surg. :
    • Ann Surg
    • Jeschke, M.G.1    Finnerty, C.C.2    Herndon, D.N.3
  • 16
    • 0033810083 scopus 로고    scopus 로고
    • Determinants of skeletal muscle catabolism after severe burn
    • Hart DW, Wolf SE, Chinkes DL, et al. Determinants of skeletal muscle catabolism after severe burn. Ann Surg. 2000 ; 232: 455-465
    • (2000) Ann Surg , vol.232 , pp. 455-465
    • Hart, D.W.1    Wolf, S.E.2    Chinkes, D.L.3
  • 20
    • 0035141473 scopus 로고    scopus 로고
    • Energy expenditure and the body cell mass in cystic fibrosis
    • DOI 10.1016/S0899-9007(00)00470-6, PII S0899900700004706
    • Shepherd RW, Greer RM, McNaughton SA, Wotton M, Cleghorn GJ. Energy expenditure and the body cell mass in cystic fibrosis. Nutrition. 2001 ; 17: 22-25 (Pubitemid 32117636)
    • (2001) Nutrition , vol.17 , Issue.1 , pp. 22-25
    • Shepherd, R.W.1    Greer, R.M.2    McNaughton, S.A.3    Wotton, M.4    Cleghorn, G.J.5
  • 21
    • 0034485454 scopus 로고    scopus 로고
    • The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly
    • DOI 10.1210/jc.85.12.4481
    • Volpi E, Mittendorfer B, Rasmussen BB, Wolfe RR. The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly. J Clin Endocrinol Metab. 2000 ; 85: 4481-4490 (Pubitemid 32157622)
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , Issue.12 , pp. 4481-4490
    • Volpi, E.1    Mittendorfer, B.2    Rasmussen, B.B.3    Wolfe, R.R.4
  • 22
    • 70149092536 scopus 로고    scopus 로고
    • Severe burn-induced endoplasmic reticulum stress and hepatic damage in mice
    • Song J, Finnerty CC, Herndon DN, Boehning D, Jeschke MG. Severe burn-induced endoplasmic reticulum stress and hepatic damage in mice. Mol Med. 2009 ; 15: 316-320
    • (2009) Mol Med , vol.15 , pp. 316-320
    • Song, J.1    Finnerty, C.C.2    Herndon, D.N.3    Boehning, D.4    Jeschke, M.G.5
  • 23
    • 27144489669 scopus 로고    scopus 로고
    • AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
    • DOI 10.1128/MCB.25.21.9554-9575.2005
    • Terai K, Hiramoto Y, Masaki M, et al. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol. 2005 ; 25: 9554-9575 (Pubitemid 41507855)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.21 , pp. 9554-9575
    • Terai, K.1    Hiramoto, Y.2    Masaki, M.3    Sugiyama, S.4    Kuroda, T.5    Hori, M.6    Kawase, I.7    Hirota, H.8
  • 24
    • 0021682541 scopus 로고
    • Altered protein kinetics in vivo after single-limb burn injury
    • Shangraw RE, Turinsky J. Altered protein kinetics in vivo after single-limb burn injury. Biochem J. 1984 ; 223: 747-753 (Pubitemid 15209064)
    • (1984) Biochemical Journal , vol.223 , Issue.3 , pp. 747-753
    • Shangraw, R.E.1    Turinsky, J.2
  • 25
    • 52449093714 scopus 로고    scopus 로고
    • Pathophysiologic response to severe burn injury
    • Jeschke MG, Chinkes DL, Finnerty CC, et al. Pathophysiologic response to severe burn injury. Ann Surg. 2008 ; 248: 387-401
    • (2008) Ann Surg , vol.248 , pp. 387-401
    • Jeschke, M.G.1    Chinkes, D.L.2    Finnerty, C.C.3
  • 26
    • 61949363968 scopus 로고    scopus 로고
    • Skeletal muscle eEF2 and 4EBP1 phosphorylation during endurance exercise is dependent on intensity and muscle fiber type
    • Rose AJ, Bisiani B, Vistisen B, Kiens B, Richter EA. Skeletal muscle eEF2 and 4EBP1 phosphorylation during endurance exercise is dependent on intensity and muscle fiber type. Am J Physiol Regul Integr Comp Physiol. 2009 ; 296: R326-333
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296 , pp. 326-333
    • Rose, A.J.1    Bisiani, B.2    Vistisen, B.3    Kiens, B.4    Richter, E.A.5
  • 27
    • 0035881737 scopus 로고    scopus 로고
    • A novel method to identify protein kinase substrates: EEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta
    • DOI 10.1093/emboj/20.16.4360
    • Knebel A, Morrice N, Cohen P. A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta. EMBO J. 2001 ; 20: 4360-4369 (Pubitemid 32772030)
    • (2001) EMBO Journal , vol.20 , Issue.16 , pp. 4360-4369
    • Knebel, A.1    Morrice, N.2    Cohen, P.3
  • 28
    • 0347627139 scopus 로고    scopus 로고
    • MTOR-mediated regulation of translation factors by amino acids
    • DOI 10.1016/j.bbrc.2003.07.015
    • Proud CG. mTOR-mediated regulation of translation factors by amino acids. Biochem Biophys Res Commun. 2004 ; 313: 429-436 (Pubitemid 37543604)
    • (2004) Biochemical and Biophysical Research Communications , vol.313 , Issue.2 , pp. 429-436
    • Proud, C.G.1
  • 29
    • 0038073062 scopus 로고    scopus 로고
    • Free radicals and lipid peroxidation mediated injury in burn trauma: The role of antioxidant therapy
    • DOI 10.1016/S0300-483X(03)00154-9
    • Horton JW. Free radicals and lipid peroxidation mediated injury in burn trauma: the role of antioxidant therapy. Toxicology. 2003 ; 189: 75-88 (Pubitemid 36725024)
    • (2003) Toxicology , vol.189 , Issue.1-2 , pp. 75-88
    • Horton, J.W.1
  • 30
    • 25444524850 scopus 로고    scopus 로고
    • Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity
    • DOI 10.1074/jbc.M502876200
    • Hahn-Windgassen A, Nogueira V, Chen CC, Skeen JE, Sonenberg N, Hay N. Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity. J Biol Chem. 2005 ; 280: 32081-32089 (Pubitemid 41361813)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.37 , pp. 32081-32089
    • Hahn-Windgassen, A.1    Nogueira, V.2    Chen, C.-C.3    Skeen, J.E.4    Sonenberg, N.5    Hay, N.6
  • 31
    • 33646785781 scopus 로고    scopus 로고
    • Regulation of protein synthesis by leucine starvation involves distinct mechanisms in mouse C2C12 myoblasts and myotubes
    • Talvas J, Obled A, Fafournoux P, Mordier S. Regulation of protein synthesis by leucine starvation involves distinct mechanisms in mouse C2C12 myoblasts and myotubes. J Nutr. 2006 ; 136: 1466-1471 (Pubitemid 43765346)
    • (2006) Journal of Nutrition , vol.136 , Issue.6 , pp. 1466-1471
    • Talvas, J.1    Obled, A.2    Fafournoux, P.3    Mordier, S.4
  • 32
    • 48949103340 scopus 로고    scopus 로고
    • Prevention and treatment of gastrointestinal dysfunction following severe burns: A summary of recent 30-year clinical experience
    • Xiao SC, Zhu SH, Xia ZF, et al. Prevention and treatment of gastrointestinal dysfunction following severe burns: a summary of recent 30-year clinical experience. World J Gastroenterol. 2008 ; 14: 3231-3235
    • (2008) World J Gastroenterol , vol.14 , pp. 3231-3235
    • Xiao, S.C.1    Zhu, S.H.2    Xia, Z.F.3
  • 33
    • 0033973894 scopus 로고    scopus 로고
    • Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats
    • Zhu L, Yang ZC, Li A, Cheng DC. Protective effect of early enteral feeding on postburn impairment of liver function and its mechanism in rats. World J Gastroenterol. 2000 ; 6: 79-83 (Pubitemid 30093068)
    • (2000) World Journal of Gastroenterology , vol.6 , Issue.1 , pp. 79-83
    • Zhu, L.1    Yang, Z.C.2    Li, A.3    Cheng, D.C.4
  • 34
    • 77957556129 scopus 로고    scopus 로고
    • The optimal time for early burn wound excision to reduce pro-inflammatory cytokine production in a murine burn injury model
    • Chang KC, Ma H, Liao WC, Lee CK, Lin CY, Chen CC. The optimal time for early burn wound excision to reduce pro-inflammatory cytokine production in a murine burn injury model. Burns. 2010 ; 36: 1059-1066
    • (2010) Burns , vol.36 , pp. 1059-1066
    • Chang, K.C.1    Ma, H.2    Liao, W.C.3    Lee, C.K.4    Lin, C.Y.5    Chen, C.C.6
  • 36
    • 0042066747 scopus 로고    scopus 로고
    • Nutrition and anabolic agents in burned patients
    • DOI 10.1016/S0305-4179(03)00069-X
    • Andel H, Kamolz LP, Horauf K, Zimpfer M. Nutrition and anabolic agents in burned patients. Burns. 2003 ; 29: 592-595 (Pubitemid 36974559)
    • (2003) Burns , vol.29 , Issue.6 , pp. 592-595
    • Andel, H.1    Kamolz, L.-P.2    Horauf, K.3    Zimpfer, M.4
  • 37
    • 0034767826 scopus 로고    scopus 로고
    • Nutritional intervention high in vitamins, protein, amino acids, and omega3 fatty acids improves protein metabolism during the hypermetabolic state after thermal injury
    • Jeschke MG, Herndon DN, Ebener C, Barrow RE, Jauch KW. Nutritional intervention high in vitamins, protein, amino acids, and omega3 fatty acids improves protein metabolism during the hypermetabolic state after thermal injury. Arch Surg. 2001 ; 136: 1301-1306 (Pubitemid 33043519)
    • (2001) Archives of Surgery , vol.136 , Issue.11 , pp. 1301-1306
    • Jeschke, M.G.1    Herndon, D.N.2    Ebener, C.3    Barrow, R.E.4    Jauch, K.-W.5


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