Antidepressant-like effect of sodium butyrate (HDAC inhibitor) and its molecular mechanism of action in the rat hippocampus

World Journal of Biological Psychiatry

Volumn 13, Issue 6, 2012, Pages 458-467

  Yamawaki, Yosuke ^a,b   Fuchikami, Manabu ^a,b   Morinobu, Shigeru ^a,b   Segawa, Masahiro ^a,b   Matsumoto, Tomoya ^a,b   Yamawaki, Shigeto ^a,b  

^a HIROSHIMA UNIVERSITY   (Japan)

^b Project of Core Research for Evolutional Science and Technology of Japan Science and Technology   (Japan)

Author keywords

Antidepressant; FST; HDACi; Histone acetylation; Transthyretin

Indexed keywords

BUTYRIC ACID; HISTONE H4; MESSENGER RNA; PREALBUMIN; SEROTONIN 2A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; FORCED SWIMMING TEST; GENE EXPRESSION; HIPPOCAMPUS; HISTONE ACETYLATION; IMMOBILIZATION; IMMUNOREACTIVITY; MALE; MAZE TEST; NONHUMAN; OPEN FIELD TEST; PROMOTER REGION; RAT; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIDEPRESSIVE AGENTS; BUTYRATES; DOWN-REGULATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HINDLIMB SUSPENSION; HIPPOCAMPUS; HISTONE DEACETYLASE INHIBITORS; HISTONES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREALBUMIN; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, SEROTONIN, 5-HT2A; RNA, MESSENGER; SODIUM COMPOUNDS; STRESS, PSYCHOLOGICAL; UP-REGULATION;

EID: 84865248291     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2011.585663     Document Type: Article

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