Radon-induced reduced apoptosis in human bronchial epithelial cells with knockdown of mitochondria DNA

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 75, Issue 18, 2012, Pages 1111-1119

  Li, Bing Yan ^a   Sun, Jing ^a   Wei, Hong ^a   Cheng, Yu Zhi ^a   Xue, Lian ^a   Cheng, Zhi Hai ^a   Wan, Jian Mei ^a   Wang, Ai Qing ^a   Hei, Tom K ^b   Tong, Jian ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHIDIUM BROMIDE; MITOCHONDRIAL DNA; RADON; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; BRONCHUS; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL TRANSFORMATION; CONTROLLED STUDY; EPITHELIUM CELL; G2 PHASE CELL CYCLE CHECKPOINT; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL;

APOPTOSIS; BRONCHI; CARCINOGENS, ENVIRONMENTAL; CELL CYCLE; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; DNA, MITOCHONDRIAL; ETHIDIUM; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTERCALATING AGENTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; RADON; RADON DAUGHTERS; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA; TOXICITY TESTS, CHRONIC;

EID: 84865247991     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287394.2012.699841     Document Type: Article

References (23)

1. Adams, J. M., and Cory S. 2007. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-37. (Pubitemid 46328466)
2. Armand, R., Channon, J. Y., Kintner, J., White, K. A., Miselis, K. A., Perez, R. P., and Lewis, L. D. 2004. The effects of ethidium bromide induced loss of mitochondrial DNA on mitochondrial phenotype and ultrastructure in a human leukemia T-cell line (MOLT-4 cells). Toxicol. Appl. Pharmacol. 196: 68-79. (Pubitemid 38393695)
3. Dasgupta, S., Hoque, M. O., Upadhyay, S., and Sidransky, D. 2008. Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer. Cancer Res. 68: 700-6. (Pubitemid 351206745)
4. Evdokimovsky, E. V., Ushakova, T. E., Kudriavtcev, A. A., and Gaziev, A. I. 2011. Alteration of mtDNA copy number, mitochondrial gene expression and extracellular DNA content in mice after irradiation at lethal dose. Radiat. Environ Biophys. 50: 181-88.
5. Fernandez-Silva, P., Enriquez, J. A., and Montoya, J. 2003. Replication and transcription of mammalian mitochondrial DNA. Exp. Physiol 88: 41-56. (Pubitemid 36150058)
6. Huang, L., Snyder, A. R., and Morgan, W. F. 2003. Radiation-induced genomic instability and its implications for radiation carcinogenesis. Oncogene 22: 5848-54. (Pubitemid 37176705)
7. International Agency for Research on Cancer. 1988. Manmade fibres and radon. IARC Monogr. Eval. Carcinogen. Risk Hum. 43: 1-300.
8. Kaufmann, W. K. 2007. Initiating the uninitiated replication of damaged DNA and carcinogenesis. Cell Cycle 6: 1460-67.
9. King, M., and Attardi, G. 1996. Isolation of human cell lines lacking mitochondrial DNA. Methods Enzymol. 264: 304-313. (Pubitemid 26089319)
10. Krewski, D., Lubin, J. H., Zielinski, J. M., Alavanja, M., Catalan, V. S., Field, R. W., Klotz, J. B., Letourneau, E. G., Lynch, C. F., Lyon, J. L., Sandler, D.P. Schoenberg, J. B., Steck, D. J., Stolwijk, J. A., Weinberg, C., and Wilcox, H. B. 2006. A combined analysis of North American case-control studies of residential radon and lung cancer. J. Toxicol. Environ. Health A 69: 533-97.
11. Li, J. X., Fu, C. L., Chen, R., Sun, J., Nie, J. H., and Tong, J. 2007. Screening of differential expression genes in bone marrow cells of radon-exposed mice. J. Toxicol. Environ. Health A 70: 964-69. (Pubitemid 46699720)
12. Marcinowski F., Lucas R. M. and Yeager W. M. 1994. National and regional distributions of airborne radon concentrations in U.S. homes. Health Phys. 66: 699-706. (Pubitemid 24177069)
13. Michelle, C. T., Daniel, K., Chen, Y., Arden, P. III, Gapstur, S., and Thun, M. J. 2011. Radon and lung cancer in the American Cancer Society cohort. Cancer Epidemiol. Biomarkers Prev. 20: 438-48.
14. Modica-Napolitano, J. S., and Singh, K. K. 2004. Mitochondrial dysfunction in cancer. Mitochondrion 4:755-62. (Pubitemid 39646820)
15. Mathur, A., Hong, Y., Kemp, B. K., Barrientos, A. A., and Erusalimskya, J. D. 2000. Evaluation of fluorescent dyes for the detection of MMP changes in cultured ardiomyocytes. Cardiovasc. Res 46: 126-38. (Pubitemid 30155953)
16. Reers, M., Smiley, S. T., Mottola-Hartshorn, C., Chen, A., Lin, M., and Chen, L. B. 1995. Mitochondrial membrane potential monitored by JC-1 dye. Methods Enzymol. 260: 406-17.
17. Palmer, A. M., Greengrass, P. M., and Cavalla, D. 2000. The role of mitochondria in apoptosis. Drug News Perspect. 13: 398-84.
18. Shidara, Y., Yamagata, K., Kanamori, T., Nakano, K., Kwong, J. Q.,Manfredi, G., Oda, H., and Ohta, S. 2005. Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res. 65: 1655-63. (Pubitemid 40478589)
19. Simone, F. 2010. Evasion of apoptosis as a cellular stress response in cancer. Int. J Cell Biol. 2010: Article ID 370835, doi:10.1155/2010/370835.
20. Singh, K. K. 2006. Mitochondria damage checkpoint, aging, and cancer. Ann. NY Acad. Sci. 1067: 182-90. (Pubitemid 43806323)
21. Smiley, S. T., Reers, M., Mottola-Hartshorn, C., Lin, M., Chen, A., Smith, T. W., Steele, G. D., Jr., and Chen, L. B. 1991. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc. Natl. Acad. Sci. USA 88: 3671-75. (Pubitemid 21916685)
22. Tse, L. A., Yu, I. T., Qiu, H., Au, J. S. K., and Wang, X.R. 2011. A case-referent study of lung cancer and incense smoke, smoking, and residential radon in Chinese men. Environ. Health Perspect. 119: 1641-46.
23. Zhou, S., Kachhap, S., Sun, W., Wu, G., Chuang, A., Poeta, L., Grumbine, L.,Mithani, S. K., Chatterjee, A., Koch, W., Westra, W. H., Maitra, A., Glazer, C., Carducci, M., Sidransky, D., McFate, T., Verma, A., and Califano, J. A. 2007. Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc. Natl. Acad. Sci. USA 104: 7540-45. (Pubitemid 47185942)