Grape seed proanthocyanidins inhibit angiogenesis via the downregulation of both vascular endothelial growth factor and angiopoietin signaling

Nutrition Research

Volumn 32, Issue 7, 2012, Pages 530-536

  Huang, Shuangsheng ^a   Yang, Ninggang ^b   Liu, Yuanyuan ^c   Hu, Lamei ^d   Zhao, Jin ^a   Gao, Jing ^a   Li, Yongquan ^a   Li, Caili ^a   Zhang, Xiaosu ^a   Huang, Tao ^a  

^a NORTH MINZU UNIVERSITY   (China)

^b Department of Urology   (China)

^c INSTITUTE OF MODERN PHYSICS   (China)

^d LANZHOU UNIVERSITY   (China)

Author keywords

Angiogenesis; Chick chorioallantoic membrane; Grape seed proanthocyanidins; HMEC 1 endothelial cells; Tie2; VEGFR2

Indexed keywords

ANGIOPOIETIN 1; EPIDERMAL GROWTH FACTOR; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PROANTHOCYANIDIN DERIVATIVE; PROTEIN TYROSINE KINASE; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ARTICLE; CHICK; CHORIOALLANTOIS; CONTROLLED STUDY; DOWN REGULATION; DOWNSTREAM PROCESSING; GRAPE; HUMAN; HUMAN CELL; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; PLANT SEED; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SYNTHESIS INHIBITION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ANGIOGENESIS INHIBITORS; ANGIOPOIETIN-1; CELL LINE; CELL MOVEMENT; CELL SURVIVAL; DOWN-REGULATION; ENDOTHELIAL CELLS; GRAPE SEED EXTRACT; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; PROANTHOCYANIDINS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

VITACEAE;

EID: 84865189613     PISSN: 02715317     EISSN: 18790739     Source Type: Journal    
DOI: 10.1016/j.nutres.2012.05.012     Document Type: Article

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