Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells

British Journal of Pharmacology

Volumn 148, Issue 6, 2006, Pages 741-751

  Zhang, Chao ^a,b   Yang, Fan ^a,b   Zhang, Xiong Wen ^a   Wang, Shun Chun ^c   Li, Mei Hong ^a,b   Lin, Li Ping ^a   Ding, Jian ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Antiangiogenesis; Grateloupia longifolia polysaccharide; HMEC 1; Tissue factor

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; MATRIGEL; MESSENGER RNA; POLYSACCHARIDE; PROTEIN; THROMBOPLASTIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ALGA; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHICK; CHORIOALLANTOIS; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG ACTIVITY; DRUG MECHANISM; ENDOTHELIUM CELL; FEMALE; GRATELOUPIA LONGIFOLIA; HUMAN; HUMAN CELL; IC 50; IMPLANTATION; IN VITRO STUDY; IN VIVO STUDY; MICROVASCULATURE; MOUSE; MOUSE STRAIN; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SARCOMA; SARCOMA CELL; TUMOR VOLUME; UMBILICAL VEIN;

ALGAE; ANGIOGENESIS INHIBITORS; ANIMALS; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; ENDOTHELIAL CELLS; EUKARYOTA; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; POLYSACCHARIDES; SARCOMA 180; THROMBOPLASTIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33746045262     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706741     Document Type: Article

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