Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-κB activation to downregulate cytokine production

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Chang, Tsung Hsien ^a   Chen, Siang Ru ^a   Yu, Chia Yi ^b   Lin, You Sheng ^a,c   Chen, Yao Shen ^a   Kubota, Toru ^d   Matsuoka, Mayumi ^d   Lin, Yi Ling ^b  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^d NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; FIBROBLAST GROWTH FACTOR RECEPTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P40; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DENDRITIC CELL; DENGUE; DENGUE VIRUS 2; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INNATE IMMUNITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROTYPE; SIGNAL TRANSDUCTION;

ANIMALS; BONE MARROW CELLS; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; CYTOKINES; DENDRITIC CELLS; DENGUE VIRUS; DOWN-REGULATION; ENZYME ACTIVATION; FEMALE; HUMANS; INTERFERON-BETA; INTERLEUKIN-10; LIGANDS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84865159736     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041635     Document Type: Article

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