HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 33, 2012, Pages 13353-13358

  Rajapaksa, Ushani S ^a,b   Li, Demin ^a   Peng, Yan Chun ^a   McMichael, Andrew J ^a   Dong, Tao ^a   Xu, Xiao Ning ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF COLOMBO   (Sri Lanka)

^c China Novartis Institutes for BioMedical Research Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; HLA A ANTIGEN; HLA B ANTIGEN; NEF PROTEIN; REV PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CD8+ T LYMPHOCYTE; CELL CLONE; CHIMERA; CONTROLLED STUDY; CYTOPLASM; CYTOTOXIC T LYMPHOCYTE; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME LINKED IMMUNOSPOT ASSAY; EXON; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HLA SYSTEM; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; INFECTION CONTROL; MOLECULAR RECOGNITION; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS RESISTANCE; WILD TYPE;

ALLELES; AMINO ACID SEQUENCE; CELL LINE; CYTOPLASM; DOWN-REGULATION; EPITOPES; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV INFECTIONS; HIV-1; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-B7 ANTIGEN; HLA-C ANTIGENS; HUMANS; MOLECULAR SEQUENCE DATA; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; POLYMORPHISM, GENETIC; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84865159572     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204199109     Document Type: Article

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