Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

Virology

Volumn 405, Issue 2, 2010, Pages 483-491

  Mkhwanazi, Nompumelelo ^a   Thobakgale, Christina F ^a   van der Stok, Mary ^a   Reddy, Shabashini ^a   Mncube, Zenele ^a   Chonco, Fundisiwe ^a   Walker, Bruce D ^a,b,c   Altfeld, Marcus ^a,b   Goulder, Philip J R ^a,d   Ndung'u, Thumbi ^a,b  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

57 5801; CD8+ T cells; HIV 1 chronic infection; HLA B; HLA C; Polyfunctionality

Indexed keywords

EPITOPE; GAG PROTEIN; GAMMA INTERFERON; HLA B ANTIGEN; HLA C ANTIGEN; INTERLEUKIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NEF PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ALLELE; ARTICLE; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRY; GENE SEQUENCE; HLA TYPING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MALE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; VIRUS LOAD; WILD TYPE;

ADULT; AMINO ACID SEQUENCE; CD4 LYMPHOCYTE COUNT; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; EPITOPES, T-LYMPHOCYTE; FEMALE; HIV INFECTIONS; HIV-1; HLA-B ANTIGENS; HLA-C ANTIGENS; HUMANS; IMMUNODOMINANT EPITOPES; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; VIRAL LOAD;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77955657060     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2010.06.002     Document Type: Article

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