Formulation and pharmacokinetics evaluation of puerarin nanocrystals for intravenous delivery

Journal of Nanoscience and Nanotechnology

Volumn 12, Issue 8, 2012, Pages 6176-6184

  Wang, Yancai ^a   Ma, Yi ^a   Ma, Yingying ^a   Du, Yongli ^a   Liu, Zhaoping ^b   Zhang, Dianrui ^b   Zhang, Qiang ^c  

^a SHANDONG POLYTECHNIC UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Dissolution; Drug Delivery; Nanocrystals; Nanomedicine; Pharmacokinetics; Puerarin

Indexed keywords

ADVERSE DRUG REACTIONS; AFM; BEAGLE DOG; CORONARY HEART DISEASE; COSOLVENTS; CRYSTALLINITIES; FREEZE-DRYING PROCESS; HIGH PRESSURE HOMOGENIZATION; IN-VITRO; MEAN PARTICLE SIZE; NEGATIVE CHARGE; PHARMACOKINETIC PARAMETERS; PLASMA PROFILES; POLYDISPERSITY INDICES; PUERARIN; REFERENCE SOLUTION; SATURATION SOLUBILITY; SPHERICAL PARTICLE; WATER SOLUBILITIES;

DISSOLUTION; DRUG DELIVERY; MEDICAL NANOTECHNOLOGY; ORGANIC COMPOUNDS; PHARMACOKINETICS; SOLUBILITY;

NANOCRYSTALS;

ISOFLAVONE DERIVATIVE; NANOPARTICLE; PUERARIN;

ANIMAL; ARTICLE; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DOG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SOLUBILITY;

ANIMALS; CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; INJECTIONS, INTRAVENOUS; ISOFLAVONES; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PARTICLE SIZE; SOLUBILITY;

EID: 84865140684     PISSN: 15334880     EISSN: 15334899     Source Type: Journal    
DOI: 10.1166/jnn.2012.6436     Document Type: Conference Paper

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