-
1
-
-
77956855090
-
Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363
-
Buchebner M, Pfeifer T, Rathke N, Chandak PG, Lass A, Schreiber R, Kratzer A, Zimmermann R, Sattler W, Koefeler H, Fröhlich E, Kostner GM, Birner-Gruenberger R, Chiang KP, Haemmerle G, Zechner R, Levak-Frank S, Cravatt B, Kratky D. Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363. J Lipid Res 51: 2896-2908, 2010.
-
(2010)
J Lipid Res
, vol.51
, pp. 2896-2908
-
-
Buchebner, M.1
Pfeifer, T.2
Rathke, N.3
Chandak, P.G.4
Lass, A.5
Schreiber, R.6
Kratzer, A.7
Zimmermann, R.8
Sattler, W.9
Koefeler, H.10
Fröhlich, E.11
Kostner, G.M.12
Birner-Gruenberger, R.13
Chiang, K.P.14
Haemmerle, G.15
Zechner, R.16
Levak-Frank, S.17
Cravatt, B.18
Kratky, D.19
-
2
-
-
0036297998
-
Hormone-sensitive lipase is not required for cholesteryl ester hydrolysis in macrophages
-
Contreras JA. Hormone-sensitive lipase is not required for cholesteryl ester hydrolysis in macrophages. Biochem Biophys Res Commun 292: 900-903, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.292
, pp. 900-903
-
-
Contreras, J.A.1
-
3
-
-
52349103153
-
Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages
-
Crow JA, Middleton BL, Borazjani A, Hatfield MJ, Potter PM, Ross MK. Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages. Biochim Biophys Acta 1781: 643-654, 2008.
-
(2008)
Biochim Biophys Acta
, vol.1781
, pp. 643-654
-
-
Crow, J.A.1
Middleton, B.L.2
Borazjani, A.3
Hatfield, M.J.4
Potter, P.M.5
Ross, M.K.6
-
4
-
-
0001265170
-
The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes
-
Deykin D, Goodman DS. The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. J Biol Chem 237: 3649-3656, 1962.
-
(1962)
J Biol Chem
, vol.237
, pp. 3649-3656
-
-
Deykin, D.1
Goodman, D.S.2
-
5
-
-
0242322491
-
Mobilization of cytoplasmic CE droplets by over-expression of human macrophage cholesteryl ester hydrolase
-
Ghosh S, St Clair RW, Rudel LL. Mobilization of cytoplasmic CE droplets by over-expression of human macrophage cholesteryl ester hydrolase. J Lipid Res 44: 1833-1840, 2003.
-
(2003)
J Lipid Res
, vol.44
, pp. 1833-1840
-
-
Ghosh, S.1
Clair, S.R.W.2
Rudel, L.L.3
-
6
-
-
0034707495
-
Cholesteryl ester hydrolase in human monocyte/macrophage: Cloning, sequencing and expression of full-length cDNA
-
Ghosh S. Cholesteryl ester hydrolase in human monocyte/macrophage: cloning, sequencing and expression of full-length cDNA. Physiol Genomics 2: 1-8, 2000.
-
(2000)
Physiol Genomics
, vol.2
, pp. 1-8
-
-
Ghosh, S.1
-
7
-
-
17444452707
-
The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption
-
Gonzalez FJ. The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption. Toxicol Lett 102-103: 161-166, 1998.
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 161-166
-
-
Gonzalez, F.J.1
-
8
-
-
0020696019
-
Arterial neutral cholesteryl esterase. A hormone-sensitive enzyme distinct from lysosomal cholesteryl esterase
-
Hajjar DP, Minick CR, Fowler S. Arterial neutral cholesteryl esterase. A hormone-sensitive enzyme distinct from lysosomal cholesteryl esterase. J Biol Chem 258: 192-198, 1983.
-
(1983)
J Biol Chem
, vol.258
, pp. 192-198
-
-
Hajjar, D.P.1
Minick, C.R.2
Fowler, S.3
-
9
-
-
77953477655
-
Mammalian carboxylesterase 3: Comparative genomics and proteomics
-
Holmes RS, Cox LA, VandeBerg JL. Mammalian carboxylesterase 3: comparative genomics and proteomics. Genetica 138: 695-708, 2010.
-
(2010)
Genetica
, vol.138
, pp. 695-708
-
-
Holmes, R.S.1
Cox, L.A.2
Vandeberg, J.L.3
-
10
-
-
78650373264
-
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages
-
Igarashi M, Osuga J, Uozaki H, Sekiya M, Nagashima S, Takahashi M, Takase S, Takanashi M, Li Y, Ohta K, Kumagai M, Nishi M, Hosokawa M, Fledelius C, Jacobsen P, Yagyu H, Fukayama M, Nagai R, Kadowaki T, Ohashi K, Ishibashi S. The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages. Circ Res 107: 1387-1395, 2010.
-
(2010)
Circ Res
, vol.107
, pp. 1387-1395
-
-
Igarashi, M.1
Osuga, J.2
Uozaki, H.3
Sekiya, M.4
Nagashima, S.5
Takahashi, M.6
Takase, S.7
Takanashi, M.8
Li, Y.9
Ohta, K.10
Kumagai, M.11
Nishi, M.12
Hosokawa, M.13
Fledelius, C.14
Jacobsen, P.15
Yagyu, H.16
Fukayama, M.17
Nagai, R.18
Kadowaki, T.19
Ohashi, K.20
Ishibashi, S.21
more..
-
11
-
-
33746793855
-
The regulatory utilization of genetic redundancy through responsive backup circuits
-
Kafri R, Levy M, Pilpel Y. The regulatory utilization of genetic redundancy through responsive backup circuits. Proc Natl Acad Sci USA 103: 11653-11658, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11653-11658
-
-
Kafri, R.1
Levy, M.2
Pilpel, Y.3
-
12
-
-
59049099861
-
Genetic redundancy: New tricks for old genes
-
Kafri R, Springer M, Pilpel Y. Genetic redundancy: new tricks for old genes. Cell 136: 389-392, 2009.
-
(2009)
Cell
, vol.136
, pp. 389-392
-
-
Kafri, R.1
Springer, M.2
Pilpel, Y.3
-
13
-
-
0034520194
-
Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
-
Lee RG, Willingham MC, Davis MA, Skinner KA, Rudel LL. Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates. J Lipid Res 41: 1991-2001, 2000.
-
(2000)
J Lipid Res
, vol.41
, pp. 1991-2001
-
-
Lee, R.G.1
Willingham, M.C.2
Davis, M.A.3
Skinner, K.A.4
Rudel, L.L.5
-
14
-
-
0030658032
-
Modified low density lipoprotein enhances the secretion of bile salt-stimulated cholesterol esterase by human monocyte-macrophages. Species-specific difference in macrophage cholesteryl ester hydrolase
-
Li F, Hui DY. Modified low density lipoprotein enhances the secretion of bile salt-stimulated cholesterol esterase by human monocyte-macrophages. Species-specific difference in macrophage cholesteryl ester hydrolase. J Biol Chem 272: 28666-28671, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 28666-28671
-
-
Li, F.1
Hui, D.Y.2
-
15
-
-
0021921470
-
A defect in the mobilization of cholesterol esters in rabbit macrophages
-
Mathur SN, Field FJ, Megan MB MB, Armstrong HL. A defect in the mobilization of cholesterol esters in rabbit macrophages. Biochim Biophys Acta 834: 48-57, 1985.
-
(1985)
Biochim Biophys Acta
, vol.834
, pp. 48-57
-
-
Mathur, S.N.1
Field, F.J.2
Megan, M.B.M.B.3
Armstrong, H.L.4
-
16
-
-
12944335303
-
Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
-
Osuga J, Ishibashi S, Oka T, Yagyu H, Tozawa R, Fujimoto A, Shionoiri F, Yahagi N, Kraemer FB, Tsutsumi O, Yamada N. Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. Proc Natl Acad Sci USA 97: 787-792, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 787-792
-
-
Osuga, J.1
Ishibashi, S.2
Oka, T.3
Yagyu, H.4
Tozawa, R.5
Fujimoto, A.6
Shionoiri, F.7
Yahagi, N.8
Kraemer, F.B.9
Tsutsumi, O.10
Yamada, N.11
-
17
-
-
0031824850
-
The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin
-
Porter JD, Rafael JA, Ragusa RJ, Brueckner JK, Trickett JI, Davies KE. The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophin. J Cell Sci 111: 1801-1811, 1998.
-
(1998)
J Cell Sci
, vol.111
, pp. 1801-1811
-
-
Porter, J.D.1
Rafael, J.A.2
Ragusa, R.J.3
Brueckner, J.K.4
Trickett, J.I.5
Davies, K.E.6
-
18
-
-
0031458386
-
Evidence for hormone-sensitive lipase mRNA expression in human monocyte/macrophages
-
Reue K, Cohen RD, Schotz MC. Evidence for hormone-sensitive lipase mRNA expression in human monocyte/macrophages. Arterioscler Thromb Vasc Biol 17: 3428-3432, 1997.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 3428-3432
-
-
Reue, K.1
Cohen, R.D.2
Schotz, M.C.3
-
19
-
-
2042544103
-
Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3
-
Sanghani SP, Quinney SK, Fredenburg TB, Davis WI, Murry DJ, Bosron WF. Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino]carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. Drug Metab Dispos 32: 505-511, 2004.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 505-511
-
-
Sanghani, S.P.1
Quinney, S.K.2
Fredenburg, T.B.3
Davis, W.I.4
Murry, D.J.5
Bosron, W.F.6
-
20
-
-
69549137840
-
Human carboxylesterases: An update on CES1, CES2 and CES3
-
Sanghani SP, Sanghani PC, Schiel MA, Bosron WF. Human carboxylesterases: an update on CES1, CES2 and CES3. Protein Pept Lett 16: 1207-1214, 2009.
-
(2009)
Protein Pept Lett
, vol.16
, pp. 1207-1214
-
-
Sanghani, S.P.1
Sanghani, P.C.2
Schiel, M.A.3
Bosron, W.F.4
-
21
-
-
69149107158
-
Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis
-
Sekiya M, Osuga J, Nagashima S, Ohshiro T, Igarashi M, Okazaki H, Takahashi M, Tazoe F, Wada T, Ohta K, Takanashi M, Kumagai M, Nishi M, Takase S, Yahagi N, Yagyu H, Ohashi K, Nagai R, Kadowaki T, Furukawa Y, Ishibashi S. Ablation of neutral cholesterol ester hydrolase 1 accelerates atherosclerosis. Cell Metab 10: 219-228, 2009.
-
(2009)
Cell Metab
, vol.10
, pp. 219-228
-
-
Sekiya, M.1
Osuga, J.2
Nagashima, S.3
Ohshiro, T.4
Igarashi, M.5
Okazaki, H.6
Takahashi, M.7
Tazoe, F.8
Wada, T.9
Ohta, K.10
Takanashi, M.11
Kumagai, M.12
Nishi, M.13
Takase, S.14
Yahagi, N.15
Yagyu, H.16
Ohashi, K.17
Nagai, R.18
Kadowaki, T.19
Furukawa, Y.20
Ishibashi, S.21
more..
-
22
-
-
77249149984
-
Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure
-
Wei E, Ben Ali Y, Lyon J, Wang H, Nelson R, Dolinsky VW, Dyck JR, Mitchell G, Korbutt GS, Lehner R. Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure. Cell Metab 11: 183-193, 2010.
-
(2010)
Cell Metab
, vol.11
, pp. 183-193
-
-
Wei, E.1
Ben, A.Y.2
Lyon, J.3
Wang, H.4
Nelson, R.5
Dolinsky, V.W.6
Dyck, J.R.7
Mitchell, G.8
Korbutt, G.S.9
Lehner, R.10
-
23
-
-
0028572571
-
Mechanism of the defect in cholesteryl ester clearance from macrophage from atherosclerosis susceptible White Carneau pigeon
-
Yancey PG, St. Clair RW. Mechanism of the defect in cholesteryl ester clearance from macrophage from atherosclerosis susceptible White Carneau pigeons. J Lipid Res 35: 2114-2129, 1994.
-
(1994)
J Lipid Re
, vol.3
, pp. 2114-212
-
-
Yancey, P.G.1
Clair, S.R.W.2
-
24
-
-
33744979992
-
Human liver cholesteryl ester hydrolase: Cloning, molecular characterization, and role in cellular cholesterol homeostasis
-
Zhao B, Natarajan R, Ghosh S. Human liver cholesteryl ester hydrolase: cloning, molecular characterization, and role in cellular cholesterol homeostasis. Physiol Genomics 23: 304-310, 2005.
-
(2005)
Physiol Genomics
, vol.23
, pp. 304-310
-
-
Zhao, B.1
Natarajan, R.2
Ghosh, S.3
-
25
-
-
34948878197
-
Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice
-
Zhao B, Song J, Chow WN, St Clair RW, Rudel LL, Ghosh S. Macrophage-specific transgenic expression of cholesteryl ester hydrolase significantly reduces atherosclerosis and lesion necrosis in Ldlr mice. J Clin Invest 117: 2983-2992, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 2983-2992
-
-
Zhao, B.1
Song, J.2
Chow, W.N.3
Clair, S.R.W.4
Rudel, L.L.5
Ghosh, S.6
-
26
-
-
33846272136
-
Stable overexpression of human macrophage cholesteryl ester hydrolase results in enhanced free cholesterol efflux from human THP1 macrophages
-
Zhao B, Song J, St Clair RW, Ghosh S. Stable overexpression of human macrophage cholesteryl ester hydrolase results in enhanced free cholesterol efflux from human THP1 macrophages. Am J Physiol Cell Physiol 292: C405-C412, 2007.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, pp. 405-412
-
-
Zhao, B.1
Song, J.2
Clair, S.R.W.3
Ghosh, S.4
|