-
1
-
-
40349098592
-
Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs
-
Hosokawa, M. Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs. Molecules, 2008, 13(2), 412-431.
-
(2008)
Molecules
, vol.13
, Issue.2
, pp. 412-431
-
-
Hosokawa, M.1
-
2
-
-
33847012142
-
Genomic structure and transcriptional regulation of the rat, mouse, and human carboxylesterase genes
-
Hosokawa, M.; Furihata, T.; Yaginuma, Y.; Yamamoto, N.; Koyano, N.; Fujii, A.; Nagahara, Y.; Satoh, T.; Chiba, K. Genomic structure and transcriptional regulation of the rat, mouse, and human carboxylesterase genes. Drug Metab. Rev., 2007, 39(1), 1-15.
-
(2007)
Drug Metab. Rev.
, vol.39
, Issue.1
, pp. 1-15
-
-
Hosokawa, M.1
Furihata, T.2
Yaginuma, Y.3
Yamamoto, N.4
Koyano, N.5
Fujii, A.6
Nagahara, Y.7
Satoh, T.8
Chiba, K.9
-
3
-
-
33748744628
-
Structure, function and regulation of carboxylesterases
-
Satoh, T.; Hosokawa, M. Structure, function and regulation of carboxylesterases. Chem. Biol. Interact., 2006, 162(3), 195-211.
-
(2006)
Chem. Biol. Interact.
, vol.162
, Issue.3
, pp. 195-211
-
-
Satoh, T.1
Hosokawa, M.2
-
4
-
-
33749030999
-
Human carboxylesterase isozymes: Catalytic properties and rational drug design
-
Imai, T. Human carboxylesterase isozymes: catalytic properties and rational drug design. Drug. Metab. Pharmacokinet., 2006, 21(3), 173-185.
-
(2006)
Drug. Metab. Pharmacokinet.
, vol.21
, Issue.3
, pp. 173-185
-
-
Imai, T.1
-
5
-
-
14644422580
-
Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics
-
Redinbo, M.R.; Potter, P.M. Keynote review: Mammalian carboxylesterases: From drug targets to protein therapeutics. Drug Discov. Today, 2005, 10(5), 313-325.
-
(2005)
Drug Discov. Today
, vol.10
, Issue.5
, pp. 313-325
-
-
Redinbo, M.R.1
Potter, P.M.2
-
6
-
-
0025723458
-
Cloning and analysis of a cDNA encoding a human liver carboxylesterase
-
Riddles, P.W.; Richards, L.J.; Bowles, M.R.; Pond, S.M. Cloning and analysis of a cDNA encoding a human liver carboxylesterase. Gene, 1991, 108(2), 289-292.
-
(1991)
Gene
, vol.108
, Issue.2
, pp. 289-292
-
-
Riddles, P.W.1
Richards, L.J.2
Bowles, M.R.3
Pond, S.M.4
-
7
-
-
0025990496
-
A serine esterase released by human alveolar macrophages is closely related to liver microsomal carboxylesterases
-
Munger, J.S.; Shi, G.P.; Mark, E.A.; Chin, D.T.; Gerard, C.; Chapman, H.A. A serine esterase released by human alveolar macrophages is closely related to liver microsomal carboxylesterases. J. Biol. Chem., 1991, 266(28), 18832-18838.
-
(1991)
J. Biol. Chem.
, vol.266
, Issue.28
, pp. 18832-18838
-
-
Munger, J.S.1
Shi, G.P.2
Mark, E.A.3
Chin, D.T.4
Gerard, C.5
Chapman, H.A.6
-
8
-
-
0030845278
-
Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver
-
Takai, S.; Matsuda, A.; Usami, Y.; Adachi, T.; Sugiyama, T.; Katagiri, Y.; Tatematsu, M.; Hirano, K. Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver. Biol. Pharm. Bull., 1997, 20(8), 869-873.
-
(1997)
Biol. Pharm. Bull.
, vol.20
, Issue.8
, pp. 869-873
-
-
Takai, S.1
Matsuda, A.2
Usami, Y.3
Adachi, T.4
Sugiyama, T.5
Katagiri, Y.6
Tatematsu, M.7
Hirano, K.8
-
9
-
-
0030809784
-
Human liver carboxylesterase hCE-1: Binding specificity for cocaine, heroin, and their metabolites and analogs
-
Brzezinski, M.R.; Spink, B.J.; Dean, R.A.; Berkman, C.E.; Cashman, J.R.; Bosron, W.F. Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs. Drug Metab. Dispos., 1997, 25(9), 1089-1096.
-
(1997)
Drug Metab. Dispos.
, vol.25
, Issue.9
, pp. 1089-1096
-
-
Brzezinski, M.R.1
Spink, B.J.2
Dean, R.A.3
Berkman, C.E.4
Cashman, J.R.5
Bosron, W.F.6
-
10
-
-
40349112463
-
Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes
-
Hosokawa, M.; Furihata, T.; Yaginuma, Y.; Yamamoto, N.; Watanabe, N.; Tsukada, E.; Ohhata, Y.; Kobayashi, K.; Satoh, T.; Chiba, K. Structural organization and characterization of the regulatory element of the human carboxylesterase (CES1A1 and CES1A2) genes. Drug Metab. Pharmacokinet., 2008, 23(1), 73-84.
-
(2008)
Drug Metab. Pharmacokinet.
, vol.23
, Issue.1
, pp. 73-84
-
-
Hosokawa, M.1
Furihata, T.2
Yaginuma, Y.3
Yamamoto, N.4
Watanabe, N.5
Tsukada, E.6
Ohhata, Y.7
Kobayashi, K.8
Satoh, T.9
Chiba, K.10
-
11
-
-
0242600811
-
Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme
-
Bencharit, S.; Morton, C.L.; Xue, Y.; Potter, P.M.; Redinbo, M.R. Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme. Nat. Struct. Biol., 2003, 10(5), 349-356.
-
(2003)
Nat. Struct. Biol.
, vol.10
, Issue.5
, pp. 349-356
-
-
Bencharit, S.1
Morton, C.L.2
Xue, Y.3
Potter, P.M.4
Redinbo, M.R.5
-
12
-
-
0030965160
-
Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin
-
DOI 10.1074/jbc.272.23.14769
-
Pindel, E.V.; Kedishvili, N.Y.; Abraham, T.L.; Brzezinski, M.R.; Zhang, J.; Dean, R.A.; Bosron, W.F. Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin. J. Biol. Chem., 1997, 272(23), 14769-14775. (Pubitemid 27251744)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.23
, pp. 14769-14775
-
-
Pindel, E.V.1
Kedishvili, N.Y.2
Abraham, T.L.3
Brzezinski, M.R.4
Zhang, J.5
Dean, R.A.6
Bosron, W.F.7
-
13
-
-
0031557664
-
Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver
-
Schwer, H.; Langmann, T.; Daig, R.; Becker, A.; Aslanidis, C.; Schmitz, G. Molecular cloning and characterization of a novel putative carboxylesterase, present in human intestine and liver. Biochem. Biophys. Res. Commun., 1997, 233(1), 117-120.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, Issue.1
, pp. 117-120
-
-
Schwer, H.1
Langmann, T.2
Daig, R.3
Becker, A.4
Aslanidis, C.5
Schmitz, G.6
-
14
-
-
0142157104
-
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis
-
Sanghani, S.P.; Quinney, S.K.; Fredenburg, T.B.; Sun, Z.; Davis, W.I.; Murry, D.J.; Cummings, O.W.; Seitz, D.E.; Bosron, W.F. Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. Clin. Cancer Res., 2003, 9(13), 4983-4991.
-
(2003)
Clin. Cancer Res.
, vol.9
, Issue.13
, pp. 4983-4991
-
-
Sanghani, S.P.1
Quinney, S.K.2
Fredenburg, T.B.3
Sun, Z.4
Davis, W.I.5
Murry, D.J.6
Cummings, O.W.7
Seitz, D.E.8
Bosron, W.F.9
-
15
-
-
0036236051
-
Current progress on esterases: From molecular structure to function
-
Satoh, T.; Taylor, P.; Bosron, W.F.; Sanghani, S.P.; Hosokawa, M.; La Du, B.N. Current progress on esterases: from molecular structure to function. Drug Metab Dispos., 2002, 30(5), 488-493.
-
(2002)
Drug Metab Dispos.
, vol.30
, Issue.5
, pp. 488-493
-
-
Satoh, T.1
Taylor, P.2
Bosron, W.F.3
Sanghani, S.P.4
Hosokawa, M.5
La Du, B.N.6
-
16
-
-
33748763019
-
Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1
-
Bencharit, S.; Edwards, C.C.; Morton, C.L.; Howard-Williams, E.L.; Kuhn, P.; Potter, P.M.; Redinbo, M.R. Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1. J. Mol. Biol., 2006, 363(1), 201-214.
-
(2006)
J. Mol. Biol.
, vol.363
, Issue.1
, pp. 201-214
-
-
Bencharit, S.1
Edwards, C.C.2
Morton, C.L.3
Howard-Williams, E.L.4
Kuhn, P.5
Potter, P.M.6
Redinbo, M.R.7
-
17
-
-
33644875050
-
The HUGO gene nomenclature database, 2006 updates
-
Eyre, T.A.; Ducluzeau, F.; Sneddon, T.P.; Povey, S.; Bruford, E.A.; Lush, M.J. The HUGO Gene Nomenclature Database, 2006 updates. Nucleic Acids Res., 2006, 34 (Database issue), D319-D321.
-
(2006)
Nucleic Acids Res.
, vol.34
, Issue.DATABASE ISSUE
-
-
Eyre, T.A.1
Ducluzeau, F.2
Sneddon, T.P.3
Povey, S.4
Bruford, E.A.5
Lush, M.J.6
-
18
-
-
0032779726
-
Human carboxylesterases in term placentae: Enzymatic characterization, molecular cloning and evidence for the existence of multiple forms
-
Yan, B.; Matoney, L.; Yang, D. Human carboxylesterases in term placentae: enzymatic characterization, molecular cloning and evidence for the existence of multiple forms. Placenta, 1999, 20(7), 599-607.
-
(1999)
Placenta
, vol.20
, Issue.7
, pp. 599-607
-
-
Yan, B.1
Matoney, L.2
Yang, D.3
-
19
-
-
33846056843
-
Entrez Gene: Gene-centered information at NCBI
-
Maglott, D.; Ostell, J.; Pruitt, K.D.; Tatusova, T. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res., 2007, 35 (Database issue), D26-D31.
-
(2007)
Nucleic Acids Res.
, vol.35
, Issue.DATABASE ISSUE
, pp. 26-31
-
-
Maglott, D.1
Ostell, J.2
Pruitt, K.D.3
Tatusova, T.4
-
20
-
-
33751527925
-
Development of bioinformatics resources for display and analysis of copy number and other structural variants in the human genome
-
Zhang, J.; Feuk, L.; Duggan, G.E.; Khaja, R.; Scherer, S.W. Development of bioinformatics resources for display and analysis of copy number and other structural variants in the human genome. Cytogenet. Genome Res., 2006, 115(3-4), 205-214.
-
(2006)
Cytogenet. Genome Res.
, vol.115
, Issue.3-4
, pp. 205-214
-
-
Zhang, J.1
Feuk, L.2
Duggan, G.E.3
Khaja, R.4
Scherer, S.W.5
-
21
-
-
12344250822
-
Function of alternative splicing
-
Stamm, S.; Ben-Ari, S.; Rafalska, I.; Tang, Y.; Zhang, Z.; Toiber, D.; Thanaraj, T.A.; Soreq, H. Function of alternative splicing. Gene, 2005, 344, 1-20.
-
(2005)
Gene
, vol.344
, pp. 1-20
-
-
Stamm, S.1
Ben-Ari, S.2
Rafalska, I.3
Tang, Y.4
Zhang, Z.5
Toiber, D.6
Thanaraj, T.A.7
Soreq, H.8
-
22
-
-
2342450548
-
Alternative splicing in disease and therapy
-
Garcia-Blanco, M.A.; Baraniak, A.P.; Lasda, E.L. Alternative splicing in disease and therapy. Nat. Biotechnol., 2004, 22(5), 535-546.
-
(2004)
Nat. Biotechnol.
, vol.22
, Issue.5
, pp. 535-546
-
-
Garcia-Blanco, M.A.1
Baraniak, A.P.2
Lasda, E.L.3
-
23
-
-
7444220147
-
Aberrant and alternative splicing in cancer
-
Venables, J.P. Aberrant and alternative splicing in cancer. Cancer Res., 2004, 64(21), 7647-7654.
-
(2004)
Cancer Res.
, vol.64
, Issue.21
, pp. 7647-7654
-
-
Venables, J.P.1
-
24
-
-
33748486517
-
AceView: A comprehensive cDNA-supported gene and transcripts annotation
-
Thierry-Mieg, D.; Thierry-Mieg, J. AceView: a comprehensive cDNA-supported gene and transcripts annotation. Genome Biol., 2006, 7(Suppl 1), S12.
-
(2006)
Genome Biol.
, vol.7
, Issue.1 SUPPL.
-
-
Thierry-Mieg, D.1
Thierry-Mieg, J.2
-
25
-
-
0027427772
-
Glycosylationdependent activity of baculovirus-expressed human liver carboxylesterases: CDNA cloning and characterization of two highly similar enzyme forms
-
Kroetz, D.L.; McBride, O.W.; Gonzalez, F.J. Glycosylationdependent activity of baculovirus-expressed human liver carboxylesterases: cDNA cloning and characterization of two highly similar enzyme forms. Biochemistry, 1993, 32(43), 11606-11617.
-
(1993)
Biochemistry
, vol.32
, Issue.43
, pp. 11606-11617
-
-
Kroetz, D.L.1
McBride, O.W.2
Gonzalez, F.J.3
-
26
-
-
34548852632
-
Expression and characterization of a human carboxylesterase 2 splice variant
-
Schiel, M.A.; Green, S.L.; Davis, W.I.; Sanghani, P.C.; Bosron, W.F.; Sanghani, S.P. Expression and characterization of a human carboxylesterase 2 splice variant. J. Pharmacol. Exp. Ther., 2007, 323(1), 94-101.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.323
, Issue.1
, pp. 94-101
-
-
Schiel, M.A.1
Green, S.L.2
Davis, W.I.3
Sanghani, P.C.4
Bosron, W.F.5
Sanghani, S.P.6
-
27
-
-
0042868357
-
Characterization of multiple promoters in the human carboxylesterase 2 gene
-
Wu, M.H.; Chen, P.; Remo, B.F.; Cook, E.H.; Jr.; Das, S.; Dolan, M.E. Characterization of multiple promoters in the human carboxylesterase 2 gene. Pharmacogenetics., 2003, 13(7), 425-435.
-
(2003)
Pharmacogenetics.
, vol.13
, Issue.7
, pp. 425-435
-
-
Wu, M.H.1
Chen, P.2
Remo, B.F.3
Cook, Jr.E.H.4
Das, S.5
Dolan, M.E.6
-
28
-
-
2042544103
-
Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1- piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1- piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3
-
Sanghani, S.P.; Quinney, S.K.; Fredenburg, T.B.; Davis, W.I.; Murry, D.J.; Bosron, W.F. Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1- piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1- piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3. Drug Metab. Dispos., 2004, 32(5), 505-511.
-
(2004)
Drug Metab. Dispos.
, vol.32
, Issue.5
, pp. 505-511
-
-
Sanghani, S.P.1
Quinney, S.K.2
Fredenburg, T.B.3
Davis, W.I.4
Murry, D.J.5
Bosron, W.F.6
-
29
-
-
0038647390
-
Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population
-
Saito, S.; Iida, A.; Sekine, A.; Kawauchi, S.; Higuchi, S.; Ogawa, C.; Nakamura, Y. Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population. J. Hum. Genet., 2003, 48(5), 249-270.
-
(2003)
J. Hum. Genet.
, vol.48
, Issue.5
, pp. 249-270
-
-
Saito, S.1
Iida, A.2
Sekine, A.3
Kawauchi, S.4
Higuchi, S.5
Ogawa, C.6
Nakamura, Y.7
-
30
-
-
4744340837
-
Pharmacogenomic assessment of carboxylesterases 1 and 2
-
Marsh, S.; Xiao, M.; Yu, J.; Ahluwalia, R.; Minton, M.; Freimuth, R.R.; Kwok, P.Y.; McLeod, H.L. Pharmacogenomic assessment of carboxylesterases 1 and 2. Genomics, 2004, 84(4), 661-668.
-
(2004)
Genomics
, vol.84
, Issue.4
, pp. 661-668
-
-
Marsh, S.1
Xiao, M.2
Yu, J.3
Ahluwalia, R.4
Minton, M.5
Freimuth, R.R.6
Kwok, P.Y.7
McLeod, H.L.8
-
31
-
-
10044263002
-
Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38
-
Charasson, V.; Bellott, R.; Meynard, D.; Longy, M.; Gorry, P.; Robert, J. Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38. Clin. Pharmacol. Ther., 2004, 76(6), 528-535.
-
(2004)
Clin. Pharmacol. Ther.
, vol.76
, Issue.6
, pp. 528-535
-
-
Charasson, V.1
Bellott, R.2
Meynard, D.3
Longy, M.4
Gorry, P.5
Robert, J.6
-
32
-
-
24944553271
-
Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2)
-
Kim, S.R.; Nakamura, T.; Saito, Y.; Sai, K.; Nakajima, T.; Saito, H.; Shirao, K.; Minami, H.; Ohtsu, A.; Yoshida, T.; Saijo, N.; Ozawa, S.; Sawada, J. Twelve novel single nucleotide polymorphisms in the CES2 gene encoding human carboxylesterase 2 (hCE-2). Drug Metab. Pharmacokinet., 2003, 18(5), 327-332.
-
(2003)
Drug Metab. Pharmacokinet.
, vol.18
, Issue.5
, pp. 327-332
-
-
Kim, S.R.1
Nakamura, T.2
Saito, Y.3
Sai, K.4
Nakajima, T.5
Saito, H.6
Shirao, K.7
Minami, H.8
Ohtsu, A.9
Yoshida, T.10
Saijo, N.11
Ozawa, S.12
Sawada, J.13
-
33
-
-
4644275987
-
Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene
-
Wu, M.H.; Chen, P.; Wu, X.; Liu, W.; Strom, S.; Das, S.; Cook, E.H.; Jr.; Rosner, G.L.; Dolan, M.E. Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene. Pharmacogenetics, 2004, 14(9), 595-605.
-
(2004)
Pharmacogenetics
, vol.14
, Issue.9
, pp. 595-605
-
-
Wu, M.H.1
Chen, P.2
Wu, X.3
Liu, W.4
Strom, S.5
Das, S.6
Cook, Jr.E.H.7
Rosner, G.L.8
Dolan, M.E.9
-
34
-
-
0345373886
-
Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: From binding promiscuity to selective inhibition
-
Bencharit, S.; Morton, C.L.; Hyatt, J.L.; Kuhn, P.; Danks, M.K.; Potter, P.M.; Redinbo, M.R. Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition. Chem. Biol., 2003, 10(4), 341-349.
-
(2003)
Chem. Biol.
, vol.10
, Issue.4
, pp. 341-349
-
-
Bencharit, S.1
Morton, C.L.2
Hyatt, J.L.3
Kuhn, P.4
Danks, M.K.5
Potter, P.M.6
Redinbo, M.R.7
-
35
-
-
44449128538
-
Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: Clinical significance and molecular basis
-
Zhu, H.J.; Patrick, K.S.; Yuan, H.J.; Wang, J.S.; Donovan, J.L.; DeVane, C.L.; Malcolm, R.; Johnson, J.A.; Youngblood, G.L.; Sweet, D.H.; Langaee, T.Y.; Markowitz, J.S. Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis. Am. J. Hum. Genet., 2008, 82(6), 1241-1248.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, Issue.6
, pp. 1241-1248
-
-
Zhu, H.J.1
Patrick, K.S.2
Yuan, H.J.3
Wang, J.S.4
Donovan, J.L.5
Devane, C.L.6
Malcolm, R.7
Johnson, J.A.8
Youngblood, G.L.9
Sweet, D.H.10
Langaee, T.Y.11
Markowitz, J.S.12
-
36
-
-
3342939961
-
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1
-
Sun, Z.; Murry, D.J.; Sanghani, S.P.; Davis, W.I.; Kedishvili, N.Y.; Zou, Q.; Hurley, T.D.; Bosron, W.F. Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1. J. Pharmacol. Exp. Ther., 2004, 310(2), 469-476.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, Issue.2
, pp. 469-476
-
-
Sun, Z.1
Murry, D.J.2
Sanghani, S.P.3
Davis, W.I.4
Kedishvili, N.Y.5
Zou, Q.6
Hurley, T.D.7
Bosron, W.F.8
-
37
-
-
24944432241
-
Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE- 2)
-
Kubo, T.; Kim, S.R.; Sai, K.; Saito, Y.; Nakajima, T.; Matsumoto, K.; Saito, H.; Shirao, K.; Yamamoto, N.; Minami, H.; Ohtsu, A.; Yoshida, T.; Saijo, N.; Ohno, Y.; Ozawa, S.; Sawada, J. Functional characterization of three naturally occurring single nucleotide polymorphisms in the CES2 gene encoding carboxylesterase 2 (HCE- 2). Drug Metab Dispos., 2005, 33(10), 1482-1487.
-
(2005)
Drug Metab Dispos.
, vol.33
, Issue.10
, pp. 1482-1487
-
-
Kubo, T.1
Kim, S.R.2
Sai, K.3
Saito, Y.4
Nakajima, T.5
Matsumoto, K.6
Saito, H.7
Shirao, K.8
Yamamoto, N.9
Minami, H.10
Ohtsu, A.11
Yoshida, T.12
Saijo, N.13
Ohno, Y.14
Ozawa, S.15
Sawada, J.16
-
38
-
-
19444380386
-
Hydrolysis of capecitabine to 5'-deoxy- 5-fluorocytidine by human carboxylesterases and inhibition by loperamide
-
Quinney, S.K.; Sanghani, S.P.; Davis, W.I.; Hurley, T.D.; Sun, Z.; Murry, D.J.; Bosron, W.F. Hydrolysis of capecitabine to 5'-deoxy- 5-fluorocytidine by human carboxylesterases and inhibition by loperamide. J. Pharmacol. Exp. Ther., 2005, 313(3), 1011-1016.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.313
, Issue.3
, pp. 1011-1016
-
-
Quinney, S.K.1
Sanghani, S.P.2
Davis, W.I.3
Hurley, T.D.4
Sun, Z.5
Murry, D.J.6
Bosron, W.F.7
-
39
-
-
0346494961
-
ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins
-
Hotelier, T.; Renault, L.; Cousin, X.; Negre, V.; Marchot, P.; Chatonnet, A. ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins. Nucleic Acids Res., 2004, 32 (Database issue), D145-D147.
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.DATABASE ISSUE
, pp. 145-147
-
-
Hotelier, T.1
Renault, L.2
Cousin, X.3
Negre, V.4
Marchot, P.5
Chatonnet, A.6
-
40
-
-
0027948970
-
Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine
-
Brzezinski, M.R.; Abraham, T.L.; Stone, C.L.; Dean, R.A.; Bosron, W.F. Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine. Biochem. Pharmacol., 1994, 48(9), 1747-1755.
-
(1994)
Biochem. Pharmacol.
, vol.48
, Issue.9
, pp. 1747-1755
-
-
Brzezinski, M.R.1
Abraham, T.L.2
Stone, C.L.3
Dean, R.A.4
Bosron, W.F.5
-
42
-
-
0031800635
-
The mammalian carboxylesterases: From molecules to functions
-
Satoh, T.; Hosokawa, M. The mammalian carboxylesterases: from molecules to functions. Annu. Rev. Pharmacol. Toxicol., 1998, 38, 257-288.
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 257-288
-
-
Satoh, T.1
Hosokawa, M.2
-
43
-
-
0025955766
-
Human liver cocaine esterases: Ethanol-mediated formation of ethylcocaine
-
Dean, R.A.; Christian, C.D.; Sample, R.H.; Bosron, W.F. Human liver cocaine esterases: ethanol-mediated formation of ethylcocaine. FASEB J., 1991, 5(12), 2735-2739.
-
(1991)
FASEB J.
, vol.5
, Issue.12
, pp. 2735-2739
-
-
Dean, R.A.1
Christian, C.D.2
Sample, R.H.3
Bosron, W.F.4
-
44
-
-
0036142253
-
Lessons from a bacterial cocaine esterase
-
Bosron, W.F.; Hurley, T.D. Lessons from a bacterial cocaine esterase. Nat. Struct. Biol., 2002, 9(1), 4-5.
-
(2002)
Nat. Struct. Biol.
, vol.9
, Issue.1
, pp. 4-5
-
-
Bosron, W.F.1
Hurley, T.D.2
-
45
-
-
33748901615
-
Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine
-
Imai, T.; Taketani, M.; Shii, M.; Hosokawa, M.; Chiba, K. Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine. Drug Metab. Dispos., 2006, 34(10), 1734-1741.
-
(2006)
Drug Metab. Dispos.
, vol.34
, Issue.10
, pp. 1734-1741
-
-
Imai, T.1
Taketani, M.2
Shii, M.3
Hosokawa, M.4
Chiba, K.5
-
46
-
-
0025959408
-
Cocaethylene: A unique cocaine metabolite displays high affinity for the dopamine transporter
-
Hearn, W.L.; Flynn, D.D.; Hime, G.W.; Rose, S.;Cofino, J.C.; Mantero-Atienza, E.; Wetli, C.V.; Mash, D.C. Cocaethylene: a unique cocaine metabolite displays high affinity for the dopamine transporter. J. Neurochem., 1991, 56(2), 698-701.
-
(1991)
J. Neurochem.
, vol.56
, Issue.2
, pp. 698-701
-
-
Hearn, W.L.1
Flynn, D.D.2
Hime, G.W.3
Rose, S.4
Cofino, J.C.5
Mantero-Atienza, E.6
Wetli, C.V.7
Mash, D.C.8
-
47
-
-
0031461193
-
Carboxylesterasemediated transesterification of meperidine (Demerol) and methylphenidate (Ritalin) in the presence of [2H6]ethanol: Preliminary in vitro findings using a rat liver preparation
-
Bourland, J.A.; Martin, D.K.; Mayersohn, M. Carboxylesterasemediated transesterification of meperidine (Demerol) and methylphenidate (Ritalin) in the presence of [2H6]ethanol: preliminary in vitro findings using a rat liver preparation. J. Pharm. Sci., 1997, 86(12), 1494-1496.
-
(1997)
J. Pharm. Sci.
, vol.86
, Issue.12
, pp. 1494-1496
-
-
Bourland, J.A.1
Martin, D.K.2
Mayersohn, M.3
-
48
-
-
36148976077
-
Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
-
Ingelman-Sundberg, M.; Sim, S.C.; Gomez, A.; Rodriguez-Antona, C. Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol. Ther., 2007, 116(3), 496-526.
-
(2007)
Pharmacol. Ther.
, vol.116
, Issue.3
, pp. 496-526
-
-
Ingelman-Sundberg, M.1
Sim, S.C.2
Gomez, A.3
Rodriguez-Antona, C.4
|