The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages

Circulation Research

Volumn 107, Issue 11, 2010, Pages 1387-1395

  Igarashi, Masaki ^a   Osuga, Jun Ichi ^d   Uozaki, Hiroshi ^b   Sekiya, Motohiro ^a   Nagashima, Shuichi ^d   Takahashi, Manabu ^a   Takase, Satoru ^a   Takanashi, Mikio ^d   Li, Yongxue ^a   Ohta, Keisuke ^a   Kumagai, Masayoshi ^a   Nishi, Makiko ^a   Hosokawa, Masakiyo ^e   Fledelius, Christian ^f   Jacobsen, Poul ^f   Yagyu, Hiroaki ^d   Fukayama, Masashi ^b   Nagai, Ryozo ^c   Kadowaki, Takashi ^a   Ohashi, Ken ^a   Ishibashi, Shun ^d   more..

^a Departments of Metabolic Diseases   (Japan)

^b Departments of Pathology   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d JICHI MEDICAL UNIVERSITY   (Japan)

^e CHIBA INSTITUTE OF SCIENCE   (Japan)

^f NOVO NORDISK A S   (Denmark)

Author keywords

Atherosclerosis; KIAA1363; Macrophage; Neutral cholesterol ester hydrolase; Reverse cholesterol transport

Indexed keywords

CHLORDANE; CHOLESTEROL ESTERASE; HORMONE SENSITIVE LIPASE; NEUTRAL CHOLESTEROL ESTER HYDROLASE 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CELL DEDIFFERENTIATION; CELL MIGRATION; CHOLESTEROL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; FOAM CELL; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; MACROPHAGE; MALE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS;

AGED; AGED, 80 AND OVER; ATHEROSCLEROSIS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELLS, CULTURED; CHOLESTEROL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; MONOCYTES; SERINE PROTEASES; STEROL ESTERASE;

EID: 78650373264     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.226613     Document Type: Article

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