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Volumn 15, Issue 3, 2012, Pages 407-419

Impact of Small Molecules Immunosuppressants on P-glycoprotein Activity and T-cell Function

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; IMMUNOSUPPRESSIVE AGENT; RAPAMYCIN; RHODAMINE 123; TACROLIMUS; VALSPODAR;

EID: 84865103197     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: 10.18433/j3g30b     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 2442543344 scopus 로고    scopus 로고
    • P-glycoprotein function in the elderly
    • Brenner SS, Klotz U. P-glycoprotein function in the elderly. Eur J Clin Pharmacol, 2004; 60(2):97-102.
    • (2004) Eur J Clin Pharmacol , vol.60 , Issue.2 , pp. 97-102
    • Brenner, S.S.1    Klotz, U.2
  • 2
    • 0035424103 scopus 로고    scopus 로고
    • HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART
    • Lucia MB, Rutella S, Leone G, Vella S, Cauda R. HIV-protease inhibitors contribute to P-glycoprotein efflux function defect in peripheral blood lymphocytes from HIV-positive patients receiving HAART. J Acquir Immune Defic Syndr, 2001; 27(4):321-330.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , Issue.4 , pp. 321-330
    • Lucia, M.B.1    Rutella, S.2    Leone, G.3    Vella, S.4    Cauda, R.5
  • 3
    • 0028217326 scopus 로고
    • Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein
    • Rao US, Scarborough GA. Direct demonstration of high affinity interactions of immunosuppressant drugs with the drug binding site of the human P-glycoprotein. Mol Pharmacol, 1994; 45(4):773-776.
    • (1994) Mol Pharmacol , vol.45 , Issue.4 , pp. 773-776
    • Rao, U.S.1    Scarborough, G.A.2
  • 4
    • 33749080965 scopus 로고    scopus 로고
    • A kinetic study of Rhodamine123 pumping by P-glycoprotein
    • Wang Y, Hao D, Stein WD, Yang L. A kinetic study of Rhodamine123 pumping by P-glycoprotein. Biochim Biophys Acta, 2006; 1758(10):1671-1676.
    • (2006) Biochim Biophys Acta , vol.1758 , Issue.10 , pp. 1671-1676
    • Wang, Y.1    Hao, D.2    Stein, W.D.3    Yang, L.4
  • 5
    • 31844444140 scopus 로고    scopus 로고
    • The molecular basis of multidrug resistance in cancer: The early years of P-glycoprotein research
    • Gottesman MM, Ling V. The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research. FEBS Lett, 2006; 580(4):998-1009.
    • (2006) FEBS Lett , vol.580 , Issue.4 , pp. 998-1009
    • Gottesman, M.M.1    Ling, V.2
  • 6
    • 0035865057 scopus 로고    scopus 로고
    • Specific MDR1. P-glycoprotein blockade inhibits human alloimmune T cell activation in vitro
    • Frank MH, Denton MD, Alexander SI, Khoury SJ, Sayegh MH, Briscoe DM. Specific MDR1. P-glycoprotein blockade inhibits human alloimmune T cell activation in vitro. J Immunol, 2001; 166(4):2451-2459.
    • (2001) J Immunol , vol.166 , Issue.4 , pp. 2451-2459
    • Frank, M.H.1    Denton, M.D.2    Alexander, S.I.3    Khoury, S.J.4    Sayegh, M.H.5    Briscoe, D.M.6
  • 7
    • 33845362976 scopus 로고    scopus 로고
    • Evaluation of human P-glycoprotein (MDR1/ABCB1) ATPase activity assay method by comparing with in vitro transport measurements: Michaelis-Menten kinetic analysis to estimate the affinity of P-glycoprotein to drugs
    • Shirasaka Y, Onishi Y, Sakurai A, Nakagawa H, Ishikawa T, Yamashita S. Evaluation of human P-glycoprotein (MDR1/ABCB1) ATPase activity assay method by comparing with in vitro transport measurements: Michaelis-Menten kinetic analysis to estimate the affinity of P-glycoprotein to drugs. Biol Pharm Bull, 2006; 29(12):2465-2471.
    • (2006) Biol Pharm Bull , vol.29 , Issue.12 , pp. 2465-2471
    • Shirasaka, Y.1    Onishi, Y.2    Sakurai, A.3    Nakagawa, H.4    Ishikawa, T.5    Yamashita, S.6
  • 8
    • 0037096609 scopus 로고    scopus 로고
    • MDR1 gene expression in peripheral blood mononuclear cells after liver transplantation
    • Grude P, Boleslawski E, Conti F, Chouzenoux S, Calmus Y. MDR1 gene expression in peripheral blood mononuclear cells after liver transplantation. Transplantation, 2002; 73(11):1824-1828.
    • (2002) Transplantation , vol.73 , Issue.11 , pp. 1824-1828
    • Grude, P.1    Boleslawski, E.2    Conti, F.3    Chouzenoux, S.4    Calmus, Y.5
  • 9
    • 0036538694 scopus 로고    scopus 로고
    • Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo
    • Meaden ER, Hoggard PG, Khoo SH, Back DJ. Determination of P-gp and MRP1 expression and function in peripheral blood mononuclear cells in vivo. J Immunol Methods, 2002; 262(1-2):159-165.
    • (2002) J Immunol Methods , vol.262 , Issue.1-2 , pp. 159-165
    • Meaden, E.R.1    Hoggard, P.G.2    Khoo, S.H.3    Back, D.J.4
  • 10
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: Molecular mechanisms and clinical relevance
    • Ling V. Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother Pharmacol, 1997; 40 Suppl:S3-8.
    • (1997) Cancer Chemother Pharmacol , vol.40 , Issue.SUPPL.
    • Ling, V.1
  • 11
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem, 1993; 62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 12
    • 33751160779 scopus 로고    scopus 로고
    • P-glycoprotein functions as a differentiation switch in antigen presenting cell maturation
    • Pendse SS, Behjati S, Schatton T, Izawa A, Sayegh MH, Frank MH. P-glycoprotein functions as a differentiation switch in antigen presenting cell maturation. Am J Transplant, 2006; 6(12):2884-2893.
    • (2006) Am J Transplant , vol.6 , Issue.12 , pp. 2884-2893
    • Pendse, S.S.1    Behjati, S.2    Schatton, T.3    Izawa, A.4    Sayegh, M.H.5    Frank, M.H.6
  • 14
    • 0035192755 scopus 로고    scopus 로고
    • P-glycoprotein (P-gp) is upregulated in peripheral T-cell subsets from solid organ transplant recipients
    • Donnenberg VS, Burckart GJ, Griffith BP, Jain AB, Zeevi A, Berg AD. P-glycoprotein (P-gp) is upregulated in peripheral T-cell subsets from solid organ transplant recipients. J Clin Pharmacol, 2001; 41(12):1271-1279.
    • (2001) J Clin Pharmacol , vol.41 , Issue.12 , pp. 1271-1279
    • Donnenberg, V.S.1    Burckart, G.J.2    Griffith, B.P.3    Jain, A.B.4    Zeevi, A.5    Berg, A.D.6
  • 15
    • 4344656740 scopus 로고    scopus 로고
    • CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus
    • Lemahieu WP, Maes BD, Verbeke K, Vanrenterghem Y. CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus. Am J Transplant, 2004; 4(9):1514-1522.
    • (2004) Am J Transplant , vol.4 , Issue.9 , pp. 1514-1522
    • Lemahieu, W.P.1    Maes, B.D.2    Verbeke, K.3    Vanrenterghem, Y.4
  • 19
    • 0038237028 scopus 로고    scopus 로고
    • Tacrolimus: A further update of its use in the management of organ transplantation
    • Scott LJ, McKeage K, Keam SJ, Plosker GL. Tacrolimus: a further update of its use in the management of organ transplantation. Drugs, 2003; 63(12):1247-1297.
    • (2003) Drugs , vol.63 , Issue.12 , pp. 1247-1297
    • Scott, L.J.1    McKeage, K.2    Keam, S.J.3    Plosker, G.L.4
  • 20
    • 0023111049 scopus 로고
    • Measurement of cyclosporine bioactivity in serum of renal transplant recipients: Development and comparison with RIA
    • Heidecke CD, Nicolaus C, Stadler J, Florack G, Bollschweiler E, Holscher M. Measurement of cyclosporine bioactivity in serum of renal transplant recipients: development and comparison with RIA. Transplant Proc, 1987; 19(1 Pt 2):1734-1736.
    • (1987) Transplant Proc , vol.19 , Issue.1-2 PART , pp. 1734-1736
    • Heidecke, C.D.1    Nicolaus, C.2    Stadler, J.3    Florack, G.4    Bollschweiler, E.5    Holscher, M.6
  • 21
    • 0022385998 scopus 로고
    • Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters
    • Kahan BD. Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters. Transplantation, 1985; 40(5):457-476.
    • (1985) Transplantation , vol.40 , Issue.5 , pp. 457-476
    • Kahan, B.D.1
  • 26
    • 0036178283 scopus 로고    scopus 로고
    • Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: A preliminary evaluation
    • Parasrampuria DA, Lantz MV, Birnbaum JL, Vincenti FG, Benet LZ. Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation. J Clin Pharmacol, 2002; 42(3):304-311.
    • (2002) J Clin Pharmacol , vol.42 , Issue.3 , pp. 304-311
    • Parasrampuria, D.A.1    Lantz, M.V.2    Birnbaum, J.L.3    Vincenti, F.G.4    Benet, L.Z.5
  • 27
    • 1042268027 scopus 로고    scopus 로고
    • Measurement of basal, substrate induced and total P-glycoprotein activity in bronchoalveolar lavage T-cell subsets
    • Donnenberg VS, Wilson JW, Burckart GJ, Zeevi A, Iacono A, Donnenberg AD. Measurement of basal, substrate induced and total P-glycoprotein activity in bronchoalveolar lavage T-cell subsets. Cytometry A, 2004; 57(2):75-85.
    • (2004) Cytometry A , vol.57 , Issue.2 , pp. 75-85
    • Donnenberg, V.S.1    Wilson, J.W.2    Burckart, G.J.3    Zeevi, A.4    Iacono, A.5    Donnenberg, A.D.6
  • 28
    • 0142029080 scopus 로고    scopus 로고
    • A kinetic study of the murine mixed lymphocyte reaction by 5,6-carboxyfluorescein diacetate succinimidyl ester labeling
    • Chen JC, Chang ML, Muench MO. A kinetic study of the murine mixed lymphocyte reaction by 5,6-carboxyfluorescein diacetate succinimidyl ester labeling. J Immunol Methods, 2003; 279(1-2):123-133.
    • (2003) J Immunol Methods , vol.279 , Issue.1-2 , pp. 123-133
    • Chen, J.C.1    Chang, M.L.2    Muench, M.O.3
  • 29
    • 0037931318 scopus 로고    scopus 로고
    • P-glycoprotein- -a novel therapeutic target for immunomodulation in clinical transplantation and autoimmunity?
    • Pendse S, Sayegh MH, Frank MH. P-glycoprotein- -a novel therapeutic target for immunomodulation in clinical transplantation and autoimmunity?. Curr Drug Targets, 2003; 4(6):469-476.
    • (2003) Curr Drug Targets , vol.4 , Issue.6 , pp. 469-476
    • Pendse, S.1    Sayegh, M.H.2    Frank, M.H.3
  • 31
    • 0035046689 scopus 로고    scopus 로고
    • A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function
    • Parasrampuria DA, Lantz MV, Benet LZ. A human lymphocyte based ex vivo assay to study the effect of drugs on P-glycoprotein (P-gp) function. Pharm Res, 2001; 18(1):39-44.
    • (2001) Pharm Res , vol.18 , Issue.1 , pp. 39-44
    • Parasrampuria, D.A.1    Lantz, M.V.2    Benet, L.Z.3
  • 32
    • 0031930884 scopus 로고    scopus 로고
    • Acute myeloid leukemia cells with low P-glycoprotein expression and high rhodamine 123 efflux capacity display high clonogenicity
    • Demur C, Muller C, Cassar G, Bousquet C, Laroche M, Laurent G. Acute myeloid leukemia cells with low P-glycoprotein expression and high rhodamine 123 efflux capacity display high clonogenicity. Leukemia, 1998; 12(2):192-199.
    • (1998) Leukemia , vol.12 , Issue.2 , pp. 192-199
    • Demur, C.1    Muller, C.2    Cassar, G.3    Bousquet, C.4    Laroche, M.5    Laurent, G.6
  • 33
    • 0026442430 scopus 로고
    • Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: A role in cytotoxic effector function
    • Gupta S, Kim CH, Tsuruo T, Gollapudi S. Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: a role in cytotoxic effector function. J Clin Immunol, 1992; 12(6):451-458.
    • (1992) J Clin Immunol , vol.12 , Issue.6 , pp. 451-458
    • Gupta, S.1    Kim, C.H.2    Tsuruo, T.3    Gollapudi, S.4
  • 34
    • 1442360354 scopus 로고    scopus 로고
    • Whole-blood cultures from renal-transplant patients stimulated ex vivo show that the effects of cyclosporine on lymphocyte proliferation are related to P-glycoprotein expression
    • Singh D, Alexander J, Owen A, Rustom R, Bone M, Hammad A, Roberts N, Park K, Pirmohamed M. Whole-blood cultures from renal-transplant patients stimulated ex vivo show that the effects of cyclosporine on lymphocyte proliferation are related to P-glycoprotein expression. Transplantation, 2004; 77(4):557-561.
    • (2004) Transplantation , vol.77 , Issue.4 , pp. 557-561
    • Singh, D.1    Alexander, J.2    Owen, A.3    Rustom, R.4    Bone, M.5    Hammad, A.6    Roberts, N.7    Park, K.8    Pirmohamed, M.9
  • 36
    • 0141989743 scopus 로고    scopus 로고
    • Cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting
    • Wang H, Hosiawa KA, Min W, Yang J, Zhang X, Garcia B, Ichim TE, Zhou D, Lian D, Kelvin DJ, Zhong R. Cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting. J Immunol, 2003;171(7):3823-3836.
    • (2003) J Immunol , vol.171 , Issue.7 , pp. 3823-3836
    • Wang, H.1    Hosiawa, K.A.2    Min, W.3    Yang, J.4    Zhang, X.5    Garcia, B.6    Ichim, T.E.7    Zhou, D.8    Lian, D.9    Kelvin, D.J.10    Zhong, R.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.