Evaluation of human P-glycoprotein (MDR1/ABCB1) ATPase activity assay method by comparing with in vitro transport measurements: Michaelis-Menten kinetic analysis to estimate the affinity of P-glycoprotein to drugs

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 12, 2006, Pages 2465-2471

  Shirasaka, Yoshiyuki ^a   Onishi, Yuko ^b   Sakurai, Aki ^b   Nakagawa, Hiroshi ^b   Ishikawa, Toshihisa ^b   Yamashita, Shinji ^a  

^a SETSUNAN UNIVERSITY   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

ABCB1; ATPase activity; High throughput; Multidrug resistance (MDR1); P glycoprotein; Sf9 insect cell

Indexed keywords

ABC TRANSPORTER; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHATE; QUINIDINE; VERAPAMIL;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG TRANSPORT; ENZYME ACTIVITY; ENZYME ASSAY; HYDROLYSIS; IN VITRO STUDY; MICHAELIS MENTEN KINETICS; NONHUMAN;

ANIMALS; CELL LINE; DOGS; HUMANS; ORGANIC ANION TRANSPORTERS; P-GLYCOPROTEIN; PHARMACOKINETICS;

EID: 33845362976     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.2465     Document Type: Article

References (26)

1. Juliano R. L., Ling V., Biochim. Biophys. Acta, 455, 152-162 (1976).
2. Ishikawa T., "Nature Publishing Group, 4, 154-160 (2003).
3. Borst P., Oude Elferink R., Ann. Rev. Biochem., 71, 537-592 (2002).
4. Thiebaut F., Tsuruo T., Hamada H., Gottesman M. M., Pastan I., Willingham M. C., Proc. Natl. Acad. Sci. U.S.A., 84, 7735-7738 (1987).
5. Hunter J., Hirst B. H., Adv. Drug Del. Rev., 25, 129-157 (1997).
6. Gao J., Murase O., Schowen R. L., Aube J., Borchardt R. T., Pharm. Res., 18, 171-176 (2001).
7. Kim R. B., Fromm M. F., Wandel C., Leake B., Wood A. J., Roden D. M., Wilkinson G. R., J. Clin. Invest., 101, 289-294 (1998).
8. Polli J. W., Jarrett J. L., Studenberg S. D., Humphreys J. E., Dennis S. W., Brouwer K. R., Woolley J. L., Pharm. Res., 16, 1206-1212 (1999).
9. Susanto M., Benet L. Z., Pharm. Res., 19, 457-462 (2002).
10. Polli J. W., Wring S. A., Humphreys J. E., Huang L., Morgan J. B., Webster L. O., Serabjit-Singh C. S., J. Pharmacol. Exp. Ther., 299, 620-628 (2001).
11. Liminga G., Nygren P., Larsson R., Exp. Cell Res., 212, 291-296 (1994).
12. Tiberghien F., Loor F., Anticancer Drugs, 7, 568-578 (1996).
13. Scarborough G. A., J. Bioenerg. Biomembr., 27, 37-41 (1995).
14. Litman T., Nielsen D., Skovsgaard T., Zeuthen T., Stein W. D., Biochim. Biophys. Acta, 1361, 147-158 (1997).
15. Ishikawa T., Hirano H., Onishi Y., Sakurai A., Tarui S., Drug Metab. Pharmacokinet., 19, 1-14 (2004).
16. Ishikawa T., Sakurai A., Kanamori Y., Nagakura M., Hirano H., Takarada Y., Yamada K., Fukushima K., Kitajima M., Methods Enzymol., 400, 485-510 (2005).
17. Litman T., Zeuthen T., Skovsgaard T., Stein W. D., Biochim. Biophys. Acta, 1361, 159-168 (1997).
18. Adachi Y., Suzuki H., Sugiyama Y., Pharm. Res., 18, 1660-1668 (2001).
19. Carter S. G., Karl D. W., J. Biochem. Biophys. Methods, 7, 7-13 (1982).
20. Sarkadi B., Price E. M., Boucher R. C., Germann U. A., Scarborough G. A., J. Biol. Chem., 267, 4854-4858 (1992).
21. Lentz K. A., Polli J. W., Wring S. A., Humphreys J. E., Polli J. E., Pharm. Res., 17, 1456-1460 (2000).
22. Yamaoka K., Tanigawara Y., Nakagawa T., Uno T., J. Pharmacobio-Dyn., 4, 879-885 (1981).
23. Drori S., Eytan G. D., Assaraf Y. G., Eur. J. Biochem., 228, 1020-1029 (1995).
24. Borgnia M. J., Eytan G. D., Assaraf Y. G., J. Biol. Chem., 271, 3163-3171 (1996).
25. Buxbaum E., Eur. J. Biochem., 265, 64-70 (1999).
26. Gottesman M. M., Pastan I., Annu. Rev. Biochem., 62, 385-427 (1993).