2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog

Toxicology and Applied Pharmacology

Volumn 263, Issue 2, 2012, Pages 203-209

  Boulware, Stephen ^b   Fields, Tammy ^a   McIvor, Elizabeth ^a   Powell, K Leslie ^a   Abel, Erika L ^a   Vasquez, Karen M ^b   MacLeod, Michael C ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Carcinogen; Electrophile; Sulfur mustard

Indexed keywords

2,6 DIMERCAPTOPURINE; CYTOKERATIN 6; DERMATOLOGICAL AGENT; HISTONE H2AX; MUSTARD GAS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; ENVIRONMENTAL EXPOSURE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; MUTAGENESIS; MUTATION RATE; NONHUMAN; PHOSPHORYLATION; SKIN PROTECTION;

ADMINISTRATION, CUTANEOUS; ANIMALS; CHEMICAL WARFARE AGENTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENETIC ENGINEERING; HISTONES; KERATIN-6; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUSTARD GAS; MUTAGENESIS; MUTATION; PHOSPHORYLATION; PURINES; SKIN; TIME FACTORS;

MUS;

EID: 84865097398     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.06.010     Document Type: Article

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