An overview of therapeutic approaches to brain tumor stem cells

Medical Journal of the Islamic Republic of Iran

Volumn 26, Issue 1, 2012, Pages 31-40

  Khoshnevisan, Alireza ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Brain tumor; Glioma; Stem cells

Indexed keywords

EID: 84865096506     PISSN: 10161430     EISSN: 22516840     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Khoshnevisan A, Muhammadnejad A, Muhammadnejad S, Mazaheri Z, Kazem haghighi M, et al. Establishment of Autochthonous & Standard Cell Line Derived Xenograft Models of Glioblastoma Multiform in Iran. BCCR 2011; 3(1):52-59.
2. Thangarajh M, Gutmann DH. Low-grade gliomas as neurodevelopmental disorders: Insights from mouse models of neurofibromatosis-1 Neuropathol Appl Neurobiol 2011 Oct 28.1365-2990.
3. Germano IM, Emdad L, Qadeer ZA, Binello E, Uzzaman M. Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. Cancer Gene Ther 2010 Sep;17(9):664-74.
4. Zhou J, Shrikhande G, Xu J, McKay RM, Burns DK, Johnson JE, Parada LF. Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle. Genes Dev. 2011;25(15):1595-600.
5. Westphal M, Lamszus K. The neurobiology of gliomas: from cell biology to the development of therapeutic approaches. Nat Rev Neurosci 2011; 12(9):495-508.
6. Amanpour S, Muhammadnejad S, Muhammadnejad A, Mazaheri Z, Kazem-Haghighi M, Oghabian M, et al. Studying angiogenesis in autochthonous xenograft models of glioblastoma multiforme by MVD-CD34 technique in Iranian patients. TUMJ 2011; 69(3): 141-145.
7. He J, Liu Y, Zhu T, Zhu J, Dimeco F, Vescovi AL, et al. CD90 is identified as a marker for cancer stem cells in primary high-grade gliomas using tissue microarrays. Mol Cell Proteomics. In press.
8. Matos Rojas IA, Bertholdo D, Castillo M. Stem cells: implications in the development of brain tumors. Radiologia. In press.
9. Alonso MM, Diez-Valle R, Manterola L, Rubio A, Liu D, Cortes-Santiago N, Genetic and epigenetic modifications of sox2 contribute to the invasive phenotype of malignant gliomas. PLoS One. 2011;6(11):e26740.
10. Yu SP, Yang XJ, Zhang B, Ming HL, Chen C, Ren BC, et al, Enhanced invasion in vitro and the distribution patterns in vivo of CD133+ glioma stem cells. Chin Med J (Engl) 2011;124(17):2599-604.
11. Sampetrean O, Saga I, Nakanishi M, Sugihara E, Fukaya R, Onishi N, Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells. Neoplasia 2011 Sep;13(9):784-91.
12. Goidts V, Bageritz J, Puccio L, Nakata S, Zapatka M, Barbus S, et al. RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival. Oncogene. In press.
13. Svendsen A, Verhoeff JJ, Immervoll H, Brøgger JC, Kmiecik J, Poli A, et al, Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. Acta Neuropathol 2011 Oct;122(4):495-510.
14. Lathia JD, Gallagher J, Myers JT, Li M, Vasanji A, McLendon RE, et al, Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. PLoS One 2011;6(9):e24807.
15. Deleyrolle LP, Harding A, Cato K, Siebzehnrubl FA, Rahman M, Azari H, Evidence for label-retaining tumour-initiating cells in human glioblastoma. Brain 2011 May;134(Pt 5):1331-43
16. Cho WC. OncomiRs: the discovery and progress of microRNAs in cancers. Mol Cancer 2007; 25(6):60.
17. Sun G, Ye P, Murai K, Lang MF, Li S, Zhang H, et al. miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. Nat Commun 2011 Nov 8;2:529.
18. de Antonellis P, Medaglia C, Cusanelli E, Andolfo I, Liguori L, De Vita G, et al. MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma. PLoS One 2011;6(9):e24584.
19. Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D, Purow B, Abounader R. microRNA-34a is tumor suppressive in brain tumors and glioma stem cells. Cell Cycle 2010 Mar, 15;9(6):1031-6
20. Welch C, Chen Y, Stallings RL. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene 2007, Jul;26(34):5017-22.
21. Yang YP, Chien Y, Chiou GY, Cherng JY, Wang ML, Lo WL, Inhibition of cancer stem celllike properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI. Biomaterials. In press.
22. Annovazzi L, Mellai M, Caldera V, Valente G, Schiffer D. SOX2 expression and amplification in gliomas and glioma cell lines. Cancer Genomics Proteomics 2011 May-Jun;8(3):139-47.
23. Sun H, Zhang S. Arsenic trioxide regulates the apoptosis of glioma cell and glioma stem cell via down-regulation of stem cell marker Sox2. Biochem Biophys Res Commun 2011 Jul 8;410(3):692-7.
24. Kanzawa T, Zhang L, Xiao L, Germano IM, Kondo Y, Kondo S. Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3. Oncogene 2005 Feb 3;24(6):980-91.
25. Papagiannakopoulos T, Friedmann-Morvinski D, Neveu P, Dugas JC, Gill RM, Huillard E, Proneural miR-128 is a glioma tumor suppressor that targets mitogenic kinases. Oncogene. In press.
26. He H, Niu CS, Li MW. Correlation between glioblastoma stem-like cells and tumor vascularization. Oncol Rep 2012 Jan;27(1):45-50.
27. Persano L, Rampazzo E, Della Puppa A, Pistollato F, Basso G. The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications. Scientific World Journal 2011;11:1829-41.
28. Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T. Tumor vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 2010 Dec, 468, 824-828.
29. Rahman M, Hoh BL. Glioblastoma multiforme tumor stem cells form endothelium. World Neurosurg 2011 Mar-Apr;75(3-4):338-9.
30. Shimizu F, Hovinga KE, Metzner M, Soulet D, Tabar V. Organotypic explant culture of glioblastoma multiforme and subsequent single-cell suspension. Curr Protoc Stem Cell Biol 2011 Dec; Chapter 3:Unit 3.5.
31. Turner JD, Sanai N. A brain tumor stem cell origin for glioblastoma endothelium. World Neurosurg. 2011 May-Jun;75(5-6):574-5.
32. Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, Hamm LL, et al. Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res. 2011 Sep 15;71 (18):6061-72.
33. Mei J, Bachoo R, Zhang CL. MicroRNA-146a inhibits glioma development by targeting Notch1. Mol Cell Biol 2011 Sep;31(17):3584-92
34. Wang J, Wang C, Meng Q, Li S, Sun X, Bo Y, Yao W. siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth. Mol Biol Rep. In press.
35. Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe, et al. E MEK-ERK Signaling Dictates DNA-Rep2air Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis. Stem Cells 2011 Dec;29(12):1942-51.
36. Jiang H, Gomez-Manzano C, Lang F, Alemany R, Fueyo J. Oncolytic adenovirus: preclinical and clinical studies in patients with human malignant gliomas. Curr Gene Ther 2009 October; 9(5): 422-427.
37. Alonso MM, Jiang H, Gomez-Manzano C, Fueyo J. Targeting brain tumor stem cells with oncolytic adenoviruses. Methods Mol Biol 2012; 797:111-25.
38. Jijiwa M, Demir H, Gupta S, Leung C, Joshi K, Orozco N, CD44v6 regulates growth of brain tumor stem cells partially through the AKTmediated pathway. PLoS ONE 2011;6(9):e24217
39. Altaner C. Glioblastoma and stem cells. Neoplasma. 2008;55(5):369-74.
40. Natsume A, Kato T, Kinjo S, Enomoto A, Toda H, Shimato S, et al Girdin maintains the stemness of glioblastoma stem cells. Oncogene In press.
41. Zhang M, Kleber S, Röhrich M, Timke C, Han N, Tuettenberg J, et al. Blockade of TGF-β Signaling by the TGFβR-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma. Cancer Res. In press.
42. Sathornsumetee S. Therapeutic Strategies to Target Multiple Kinases in Glioblastoma. Anticancer Agents Med Chem. In press.
43. Kim MJ, Kim RK, Yoon CH, An S, Hwang SG, Suh Y, et al. Importance of PKCδ signaling in fractionated-radiation-induced expansion of gliomainitiating cells and resistance to cancer treatment. J Cell Sci 2011 Sep 15;124(Pt 18):3084-94.
44. Azoitei N, Kleger A, Schoo N, Thal DR, Brunner C, Pusapati GV, et al. Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation. Neuro Oncol 2011 Jul;13(7):710-24.
45. Moon JH, Kwon S, Jun EK, Kim A, Whang KY, Kim H, et al. Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells. Biochem Biophys Res Commun 2011 Aug 19;412(1):175-81.
46. Liu C, Sage JC, Miller MR, Verhaak RG, Hippenmeyer S, Vogel H et al. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 2011 Jul 22;146(2):209-21.
47. Niu CS, Li DX, Liu YH, Fu XM, Tang SF, Li J. Expression of NANOG in human gliomas and its relationship with undifferentiated glioma cells. Oncol Rep 2011 Sep;26(3):593-601.
48. Zbinden M, Duquet A, Lorente-Trigos A, Ngwabyt SN, Borges I, Ruiz i Altaba A. NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. EMBO J 2010 Aug 4;29(15):2659-74.
49. Balyasnikova IV, Ferguson SD, Han Y, Liu F, Lesniak MS. Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts. Cancer Lett 2011 Nov 28; 310(2):148-59
50. Balyasnikova IV, Ferguson SD, Han Y, Liu F, Lesniak MS. Therapeutic effect of neural stem cells expressing TRAIL and bortezomib in mice with glioma xenografts. Cancer Lett 2011 Nov 28; 310(2):148-59.
51. Balbuena J, Pachon G, Lopez-Torrents G, Aran JM, Castresana JS, Petriz J. ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties. Cytometry A 2011 Sep;79(9):672-83.
52. Fareh M, Turchi L, Virolle V, Debruyne D, Almairac F, de-la-Forest Divonne S, et al. The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network. Cell Death Differ. In press.
53. Gupta S, Takebe N, Lorusso P. Targeting the Hedgehog pathway in cancer. Ther Adv Med Oncol 2010 Jul;2(4):237-50.
54. Wang X, Venugopal C, Manoranjan B, McFarlane N, O'Farrell E, Nolte S, et al. Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells. Oncogene. In press.
55. Chernov AV, Strongin AY. Epigenetic regulation of matrix metalloproteinases and their collagen substrates in cancer. Biomol Concepts 2011 Jun;2(3):135-147.
56. Fotovati A, Abu-Ali S, Wang PS, Deleyrolle LP, Lee C, Triscott J, et al. YB-1 bridges neural stem cells and brain tumor-initiating cells via its roles in differentiation and cell growth. Cancer Res 2011 Aug 15;71(16):5569-78.
57. Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 2011 Jul 8; 146(1):53-6.
58. Katsetos CD, Dráber P, Kavallaris M. Targeting III-Tubulin in Glioblastoma Multiforme: From Cell Biology And Histopathology To Cancer Therapeutics. Anticancer Agents Med Chem. In press.
59. Avril T, Vauleon E, Hamlat A, Saikali S, Etcheverry A, Delmas C, et al. Human Glioblastoma Stem-Like Cells are More Sensitive to Allogeneic NK and T Cell-Mediated Killing Compared with Serum-Cultured Glioblastoma Cells. Brain Pathol. In press.
60. Beatus P, Jhaveri DJ, Walker TL, Lucas PG, Rietze RL, Cooper HM, et al. Oncostatin M regulates neural precursor activity in the adult brain. Dev Neurobiol 2011 Jul;71(7):619-33.
61. Tabuse M, Ohta S, Ohashi Y, Fukaya R, Misawa A, Yoshida K, et al. Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells. Mol Cancer 2011 May 22;10:60.
62. Nakano I, Joshi K, Visnyei K, Hu B, Watanabe M, Lam D, et al. Siomycin A targets brain tumor stem cells partially through a MELKmediated pathway. Neuro Oncol 2011;13(6):622-34
63. Heddleston JM, Wu Q, Rivera M, Minhas S, Lathia JD, Sloan AE, et al. Hypoxia-induced mixedlineage leukemia 1 regulates glioma stem cell tumorigenic potential. Cell Death Differ. In press.
64. Mao XG, Yan M, Xue XY, Zhang X, Ren HG, Guo G, et al. Overexpression of ZNF217 in glioblastoma contributes to the maintenance of glioma stem cells regulated by hypoxia-inducible factors. Lab Invest 2011 Jul;91(7):1068-78
65. Altaner C. Glioblastoma and stem cells. Neoplasma 2008;55(5):369-74.