Additive mixture effects of estrogenic chemicals in human cell-based assays can be influenced by inclusion of chemicals with differing effect profiles

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Evans, Richard Mark ^a   Scholze, Martin ^a   Kortenkamp, Andreas ^a  

^a BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 METHYLBENZYLIDENE)CAMPHOR; 4 HYDROXYBENZOIC ACID ESTER; 4,4' ISOPROPYLIDENEDIPHENOL; ANTIOXIDANT; BENZO[A]PYRENE; BUTYL PARABEN; BUTYLCRESOL; CADMIUM CHLORIDE; COUMESTROL; ENTEROLACTONE; ESTRADIOL; ETHINYLESTRADIOL; FLUORANTHENE; GALAXOLIDE; GENISTEIN; HETEROCYCLIC AMINE; LEAD NITRATE; METAL; METHYL PARABEN; MUSK; NARINGENIN; OXYBENZONE; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIETHYL ESTER; PHYTOESTROGEN; PLASTICIZER; POLYCHLORINATED BIPHENYL; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROPYL PARABEN;

ARTICLE; CELL ASSAY; CELL PROLIFERATION; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ESTROGEN ACTIVITY; ESTROGENICITY ASSAY MITOGENIC ENDPOINT ASSAY; ESTROGENICITY ASSAY REPORTER GENE ENDPOINT ASSAY; FILTER; HORMONE DETERMINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERMETHOD COMPARISON; PREDICTION; REFERENCE VALUE; REPORTER GENE; TISSUE LEVEL; ULTRAVIOLET RADIATION FILTER;

BIOLOGICAL ASSAY; CELL LINE, TUMOR; CELL PROLIFERATION; COMPLEX MIXTURES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ESTRADIOL; ESTROGENS; HUMANS; MCF-7 CELLS; PHYTOESTROGENS; PLASTICIZERS; POLYCHLORINATED BIPHENYLS; REPRODUCIBILITY OF RESULTS;

EID: 84865081994     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043606     Document Type: Article

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