Joint effects of heterogeneous estrogenic chemicals in the E-Screen-exploring the applicability of concentration addition

Toxicological Sciences

Volumn 122, Issue 2, 2011, Pages 383-394

  Silva, Elisabete ^a   Rajapakse, Nissanka ^a   Scholze, Martin ^a   Backhaus, Thomas ^b   Ermler, Sibylle ^a   Kortenkamp, Andreas ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Cytochrome P450; E Screen; Endocrine disrupters; Mixtures; Xenoestrogens

Indexed keywords

ANTIANDROGEN; ANTIESTROGEN; ANTITHYROID AGENT; COSMETIC; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; CYTOCHROME P450 3A4; ENDOCRINE DISRUPTOR; ESTRADIOL; ESTROGEN; PESTICIDE; PHYTOESTROGEN; STEROID HORMONE;

ACCURACY; ARTICLE; ASSAY; BREAST CANCER; CANCER CELL; CHEMICAL ANALYSIS; CONCENTRATION ADDITION; CONTROLLED STUDY; E SCREEN ASSAY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; EXPERIMENTAL MODEL; HORMONE DETERMINATION; HORMONE METABOLISM; HUMAN; HUMAN CELL; PROTEIN EXPRESSION;

ARYL HYDROCARBON HYDROXYLASES; CELL LINE, TUMOR; COMPLEX MIXTURES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP3A; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENDOCRINE DISRUPTORS; ESTROGENS; FEMALE; HUMANS; NONLINEAR DYNAMICS; PESTICIDES; PHYTOESTROGENS; REGRESSION ANALYSIS; RISK ASSESSMENT;

EID: 80051690011     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr103     Document Type: Article

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