A new type of signal peptidase cleavage site identified in an RNA virus polyprotein

Journal of Biological Chemistry

Volumn 285, Issue 12, 2010, Pages 8572-8584

  Bintintan, Ioana ^a   Meyers, Gregor ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; C TERMINUS; C-TERMINAL REGIONS; CLEAVAGE SITES; HYDROPHOBIC REGIONS; MEMBRANE ANCHORS; MEMBRANE TOPOLOGY; RNA VIRUS; SIGNAL PEPTIDASE; STRUCTURAL PROTEINS; TRANSMEMBRANE REGIONS;

ENZYME ACTIVITY; HYDROPHOBICITY; PROTEINS; RNA;

VIRUSES;

GLYCOPROTEIN E RNS; GLYCOPROTEIN E1; POLYPROTEIN; SIGNAL PEPTIDASE; UNCLASSIFIED DRUG; GLYCOPROTEIN; MEMBRANE PROTEIN; SERINE PROTEINASE; TYPE I SIGNAL PEPTIDASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE MUTATION; GLYCOSYLATION; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; RNA VIRUS; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; HAMSTER; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; PLASMID; PROTEIN TERTIARY STRUCTURE;

FLAVIVIRIDAE; RNA VIRUSES;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CRICETINAE; GLYCOPROTEINS; GLYCOSYLATION; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PLASMIDS; POLYPROTEINS; PROTEIN STRUCTURE, TERTIARY; RNA VIRUSES; SERINE ENDOPEPTIDASES;

EID: 77950560631     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.083394     Document Type: Article

References (71)

1. Heinz, F. X., Collett, M. S., Purcell, R. H., Gould, E. A., Howard, C. R., Houghton, M., Moormann, J. M., Rice, C. M., and Thiel, H. J. (2000) in Virus Taxonomy: Seventh Report of the International Committee on Taxonomy of Viruses (van Regenmortel, M. H. V., Fauquet, C. M., Bishop, D. H. L., Carstens, E. B., Estes, M. K., Lemon, S. M., Maniloff, J., Mayo, M. A., McGeoch, D. J., Pringle, C. R., and Wickner, R. B., eds) pp. 859-878, Academic Press, Inc., San Diego, CA
2. Lindenbach, B. D., Thiel, H.-J., and Rice, C. M. (2007) in Fields Virology (Knipe, D. M., and Howley, P. M., eds) pp. 1101-1152, Lippincott-Raven Publishers, Philadelphia
3. Collett, M. S., Larson, R., Belzer, S. K., and Retzel, E. (1988) Virology 165, 200-208
4. Collett, M. S., Moennig, V., and Horzinek, M. C. (1989) J. Gen. Virol. 70, 253-266
5. Elbers, K., Tautz, N., Becher, P., Stoll, D., Rümenapf, T., and Thiel, H. J. (1996) J. Virol. 70, 4131-4135
6. Harada, T., Tautz, N., and Thiel, H. J. (2000) J. Virol. 74, 9498-9506
7. Heimann, M., Roman-Sosa, G., Martoglio, B., Thiel, H. J., and Rümenapf, T. (2006) J. Virol. 80, 1915-1921
8. Lackner, T., Müller, A., König, M., Thiel, H. J., and Tautz, N. (2005) J. Virol. 79, 9746-9755
9. Rümenapf, T., Unger, G., Strauss, J. H., and Thiel, H. J. (1993) J. Virol. 67, 3288-3294
10. Tautz, N., Elbers, K., Stoll, D., Meyers, G., and Thiel, H. J. (1997) J. Virol. 71, 5415-5422
11. Wiskerchen, M., Belzer, S. K., and Collett, M. S. (1991) J. Virol. 65, 4508-4514
12. Xu, J., Mendez, E., Caron, P. R., Lin, C., Murcko, M. A., Collett, M. S., and Rice, C. M. (1997) J. Virol. 71, 5312-5322
13. Thiel, H. J., Stark, R., Weiland, E., Rümenapf, T., and Meyers, G. (1991) J. Virol. 65, 4705-4712
14. Weiland, F., Weiland, E., Unger, G., Saalmüller, A., and Thiel, H. J. (1999) J. Gen. Virol. 80, 1157-1165
15. Bolin, S., Moennig, V., Kelso Gourley, N. E., and Ridpath, J. (1988) Arch. Virol. 99, 117-123
16. Donis, R. O., Corapi, W., and Dubovi, E. J. (1988) J. Gen. Virol. 69, 77-86
17. Weiland, E., Stark, R., Haas, B., Rümenapf, T., Meyers, G., and Thiel, H. J. (1990) J. Virol. 64, 3563-3569
18. Weiland, E., Ahl, R., Stark, R., Weiland, F., and Thiel, H. J. (1992) J. Virol. 66, 3677-3682
19. König, M., Lengsfeld, T., Pauly, T., Stark, R., and Thiel, H. J. (1995) J. Virol. 69, 6479-6486
20. Horiuchi, H., Yanai, K., Takagi, M., Yano, K., Wakabayashi, E., Sanda, A., Mine, S., Ohgi, K., and Irie, M. (1988) J. Biochem. 103, 408-418
21. Hulst, M. M., and Moormann, R. J. (2001) Methods Enzymol. 342, 431-440
22. Schneider, R., Unger, G., Stark, R., Schneider-Scherzer, E., and Thiel, H. J. (1993) Science 261, 1169-1171
23. Hausmann, Y., Roman-Sosa, G., Thiel, H. J., and Rümenapf, T. (2004) J. Virol. 78, 5507-5512
24. Hulst, M. M., Himes, G., Newbigin, E., and Moormann, R. J. (1994) Virology 200, 558-565
25. Windisch, J. M., Schneider, R., Stark, R., Weiland, E., Meyers, G., and Thiel, H. J. (1996) J. Virol. 70, 352-358
26. Meyer, C., Von Freyburg, M., Elbers, K., and Meyers, G. (2002) J. Virol. 76, 8494-8503
27. Meyers, G., Saalmüller, A., and Büttner, M. (1999) J. Virol. 73, 10224-10235
28. Iqbal, M., Poole, E., Goodbourn, S., and McCauley, J. W. (2004) J. Virol. 78, 136-145
29. Magkouras, I., Mätzener, P., Rümenapf, T., Peterhans, E., and Schweizer, M. (2008) J. Gen. Virol. 89, 2501-2506
30. Mätzener, P., Magkouras, I., Rümenapf, T., Peterhans, E., and Schweizer, M. (2009) Virus Res. 140, 15-23
31. Meyers, G., Ege, A., Fetzer, C., von Freyburg, M., Elbers, K., Carr, V., Prentice, H., Charleston, B., and Schürmann, E. M. (2007) J. Virol. 81, 3327-3338
32. Tews, B. A., and Meyers, G. (2007) J. Biol. Chem. 282, 32730-32741
33. Fetzer, C., Tews, B. A., and Meyers, G. (2005) J. Virol. 79, 11901-11913
34. Langedijk, J. P. (2002) J. Biol. Chem. 277, 5308-5314
35. von Heijne, G. (1990) J. Membr. Biol. 115, 195-201
36. von Heijne, G. (1986) Nucleic Acids Res. 14, 4683-4690
37. Wyatt, L. S., Moss, B., and Rozenblatt, S. (1995) Virology 210, 202-205
38. Sambrook, J., and Russell, D. W. (2001) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
39. Meyers, G., Thiel, H. J., and Rümenapf, T. (1996) J. Virol. 70, 1588-1595
40. Devereux, J., Haeberli, P., and Smithies, O. A. (1984) Nucleic Acids Res. 12, 387-395
41. Shmulevitz, M., and Duncan, R. (2000) EMBO J. 19, 902-912
42. Kessler, S. W. (1981) Methods Enzymol. 73, 442-459
43. Meyers, G., Tautz, N., Becher, P., Thiel, H. J., and Kümmerer, B. M. (1996) J. Virol. 70, 8606-8613
44. Fujiwara, T., Oda, K., Yokota, S., Takatsuki, A., and Ikehara, Y. (1988) J. Biol. Chem. 263, 18545-18552
45. Lippincott-Schwartz, J., Yuan, L. C., Bonifacino, J. S., and Klausner, R. D. (1989) Cell 56, 801-813
46. Misumi, Y., Misumi, Y., Miki, K., Takatsuki, A., Tamura, G., and Ikehara, Y. (1986) J. Biol. Chem. 261, 11398-11403
47. Oda, K., Hirose, S., Takami, N., Misumi, Y., Takatsuki, A., and Ikehara, Y. (1987) FEBS Lett. 214, 135-138
48. Wieland, F. T., Gleason, M. L., Serafini, T. A., and Rothman, J. E. (1987) Cell 50, 289-300
49. Casanova, C. L., Xue, G., Taracha, E. L., and Dobbelaere, D. A. (2006) Mol. Biochem. Parasitol. 149, 144-154
50. Nilsson, I., Johnson, A. E., and von Heijne, G. (2002) FEBS Lett. 516, 106-108
51. Nilsson, I., Johnson, A. E., and von Heijne, G. (2003) J. Biol. Chem. 278, 29389-29393
52. van Geest, M., Nilsson, I., von Heijne, G., and Lolkema, J. S. (1999) J. Biol. Chem. 274, 2816-2823
53. Martoglio, B. (2003) Biochem. Soc. Trans. 31, 1243-1247
54. Weihofen, A., Lemberg, M. K., Ploegh, H. L., Bogyo, M., and Martoglio, B. (2000) J. Biol. Chem. 275, 30951-30956
55. Weihofen, A., Binns, K., Lemberg, M. K., Ashman, K., and Martoglio, B. (2002) Science 296, 2215-2218
56. Lau, J. T., Welply, J. K., Shenbagamurthi, P., Naider, F., and Lennarz, W. J. (1983) J. Biol. Chem. 258, 15255-15260
57. Reimann, I., Semmler, I., and Beer, M. (2007) Virology 366, 377-386
58. Widjojoatmodjo, M. N., van Gennip, H. G., Bouma, A., van Rijn, P. A., and Moormann, R. J. (2000) J. Virol. 74, 2973-2980
59. Wegelt, A., Reimann, I., Zemke, J., and Beer, M. (2009) J. Gen. Virol. 90, 2462-2467
60. von Heijne G. (1985) J. Mol. Biol. 184, 99-105
61. von Heijne G. (1984) J. Mol. Biol. 173, 243-251
62. Jackson, R. C., and Blobel, G. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5598-5602
63. Jackson, R. C., and Blobel, G. (1980) Ann. N.Y. Acad. Sci. 343, 391-404
64. Lively, M. O. (1989) Curr. Opin. Cell Biol. 1, 1188-1193
65. Lively, M. O., Newsome, A. L., and Nusier, M. (1994) Methods Enzymol. 244, 301-314
66. Paetzel, M., Karla, A., Strynadka, N. C., and Dalbey, R. E. (2002) Chem. Rev. 102, 4549-4580
67. Nilsson, I., Whitley, P., and von Heijne, G. (1994) J. Cell Biol. 126, 1127-1132
68. Karla, A., Lively, M. O., Paetzel, M., and Dalbey, R. (2005) J. Biol. Chem. 280, 6731-6741
69. von Heijne G. (1998) Nature 396, 111, 113
70. Choo, K. H., and Ranganathan, S. (2008) BMC Bioinformatics 9, Suppl. 12, S15
71. Seidah, N. G., Mowla, S. J., Hamelin, J., Mamarbachi, A. M., Benjannet, S., Touré, B. B., Basak, A., Munzer, J. S., Marcinkiewicz, J., Zhong, M., Barale, J. C., Lazure, C., Murphy, R. A., Chrétien, M., and Marcinkiewicz, M. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 1321-1326