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Volumn 7, Issue 8, 2012, Pages

The adaptor protein SAP directly associates with CD3ζ chain and regulates T cell receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD3ZETA CHAIN; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA1; PROTEIN KINASE B; SHORT HAIRPIN RNA; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; T LYMPHOCYTE ANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 84865059187     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043200     Document Type: Article
Times cited : (27)

References (52)
  • 1
    • 0035063939 scopus 로고    scopus 로고
    • X-linked lymphoproliferative disease: a progressive immunodeficiency
    • Morra M, Howie D, Grande MS, Sayos J, Wang N, et al. ((2001)) X-linked lymphoproliferative disease: a progressive immunodeficiency. Annu Rev Immunol 19:: 657--682.
    • (2001) Annu Rev Immunol , vol.19 , pp. 657-682
    • Morra, M.1    Howie, D.2    Grande, M.S.3    Sayos, J.4    Wang, N.5
  • 2
    • 17344372694 scopus 로고    scopus 로고
    • Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
    • Coffey AJ, Brooksbank RA, Brandau O, Oohashi T, Howell GR, et al. ((1998)) Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nat Genet 20:: 129--135.
    • (1998) Nat Genet , vol.20 , pp. 129-135
    • Coffey, A.J.1    Brooksbank, R.A.2    Brandau, O.3    Oohashi, T.4    Howell, G.R.5
  • 3
    • 13144278345 scopus 로고    scopus 로고
    • Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome
    • Nichols KE, Harkin DP, Levitz S, Krainer M, Kolquist KA, et al. ((1998)) Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc Natl Acad Sci U S A 95:: 13765--13770.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13765-13770
    • Nichols, K.E.1    Harkin, D.P.2    Levitz, S.3    Krainer, M.4    Kolquist, K.A.5
  • 4
    • 0032190081 scopus 로고    scopus 로고
    • The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
    • Sayos J, Wu C, Morra M, Wang N, Zhang X, et al. ((1998)) The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature 395:: 462--469.
    • (1998) Nature , vol.395 , pp. 462-469
    • Sayos, J.1    Wu, C.2    Morra, M.3    Wang, N.4    Zhang, X.5
  • 5
    • 0016772968 scopus 로고
    • X-linked recessive progressive combined variable immunodeficiency (Duncan's disease)
    • Purtilo DT, Cassel CK, Yang JP, Harper R, ((1975)) X-linked recessive progressive combined variable immunodeficiency (Duncan's disease). Lancet 1:: 935--940.
    • (1975) Lancet , vol.1 , pp. 935-940
    • Purtilo, D.T.1    Cassel, C.K.2    Yang, J.P.3    Harper, R.4
  • 6
    • 77955484327 scopus 로고    scopus 로고
    • SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions
    • Detre C, Keszei M, Romero X, Tsokos GC, Terhorst C, ((2010)) SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin Immunopathol 32:: 157--171.
    • (2010) Semin Immunopathol , vol.32 , pp. 157-171
    • Detre, C.1    Keszei, M.2    Romero, X.3    Tsokos, G.C.4    Terhorst, C.5
  • 7
    • 34247892632 scopus 로고    scopus 로고
    • Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules
    • Ma CS, Nichols KE, Tangye SG, ((2007)) Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules. Annu Rev Immunol 25:: 337--379.
    • (2007) Annu Rev Immunol , vol.25 , pp. 337-379
    • Ma, C.S.1    Nichols, K.E.2    Tangye, S.G.3
  • 8
    • 58149099175 scopus 로고    scopus 로고
    • SLAM receptors and SAP influence lymphocyte interactions, development and function
    • Schwartzberg PL, Mueller KL, Qi H, Cannons JL, ((2009)) SLAM receptors and SAP influence lymphocyte interactions, development and function. Nat Rev Immunol 9:: 39--46.
    • (2009) Nat Rev Immunol , vol.9 , pp. 39-46
    • Schwartzberg, P.L.1    Mueller, K.L.2    Qi, H.3    Cannons, J.L.4
  • 9
    • 77955272838 scopus 로고    scopus 로고
    • SLAM-family receptors: immune regulators with or without SAP-family adaptors
    • Veillette A, ((2010)) SLAM-family receptors: immune regulators with or without SAP-family adaptors. Cold Spring Harb Perspect Biol 2:: a002469.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • Veillette, A.1
  • 11
    • 0035340798 scopus 로고    scopus 로고
    • CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A
    • Shlapatska LM, Mikhalap SV, Berdova AG, Zelensky OM, Yun TJ, et al. ((2001)) CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. J Immunol 166:: 5480--5487.
    • (2001) J Immunol , vol.166 , pp. 5480-5487
    • Shlapatska, L.M.1    Mikhalap, S.V.2    Berdova, A.G.3    Zelensky, O.M.4    Yun, T.J.5
  • 12
    • 78049408674 scopus 로고    scopus 로고
    • Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation
    • Cannons JL, Wu JZ, Gomez-Rodriguez J, Zhang J, Dong B, et al. ((2010)) Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation. J Immunol 185:: 2819--2827.
    • (2010) J Immunol , vol.185 , pp. 2819-2827
    • Cannons, J.L.1    Wu, J.Z.2    Gomez-Rodriguez, J.3    Zhang, J.4    Dong, B.5
  • 13
    • 33749243738 scopus 로고    scopus 로고
    • The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation
    • Gu C, Tangye SG, Sun X, Luo Y, Lin Z, et al. ((2006)) The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation. Proc Natl Acad Sci U S A 103:: 14447--14452.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 14447-14452
    • Gu, C.1    Tangye, S.G.2    Sun, X.3    Luo, Y.4    Lin, Z.5
  • 14
    • 0037322612 scopus 로고    scopus 로고
    • Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation
    • Latour S, Roncagalli R, Chen R, Bakinowski M, Shi X, et al. ((2003)) Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation. Nat Cell Biol 5:: 149--154.
    • (2003) Nat Cell Biol , vol.5 , pp. 149-154
    • Latour, S.1    Roncagalli, R.2    Chen, R.3    Bakinowski, M.4    Shi, X.5
  • 15
    • 56949098139 scopus 로고    scopus 로고
    • The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation
    • Li C, Schibli D, Li S, ((2009)) The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation. Cellular Signalling 21:: 111--119.
    • (2009) Cellular Signalling , vol.21 , pp. 111-119
    • Li, C.1    Schibli, D.2    Li, S.3
  • 16
    • 24744437566 scopus 로고    scopus 로고
    • Impaired Ig class switch in mice deficient for the X-linked lymphoproliferative disease gene Sap
    • Al-Alem U, Li C, Forey N, Relouzat F, Fondaneche MC, et al. ((2005)) Impaired Ig class switch in mice deficient for the X-linked lymphoproliferative disease gene Sap. Blood 106:: 2069--2075.
    • (2005) Blood , vol.106 , pp. 2069-2075
    • Al-Alem, U.1    Li, C.2    Forey, N.3    Relouzat, F.4    Fondaneche, M.C.5
  • 17
    • 59749096516 scopus 로고    scopus 로고
    • SAP binds to CD22 and regulates B cell inhibitory signaling and calcium flux
    • Ostrakhovitch EA, Wang Y, Li SS, ((2009)) SAP binds to CD22 and regulates B cell inhibitory signaling and calcium flux. Cell Signal 21:: 540--550.
    • (2009) Cell Signal , vol.21 , pp. 540-550
    • Ostrakhovitch, E.A.1    Wang, Y.2    Li, S.S.3
  • 18
    • 15444374149 scopus 로고    scopus 로고
    • Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product
    • Pasquier B, Yin L, Fondaneche MC, Relouzat F, Bloch-Queyrat C, et al. ((2005)) Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product. J Exp Med 201:: 695--701.
    • (2005) J Exp Med , vol.201 , pp. 695-701
    • Pasquier, B.1    Yin, L.2    Fondaneche, M.C.3    Relouzat, F.4    Bloch-Queyrat, C.5
  • 19
    • 14844339362 scopus 로고    scopus 로고
    • Signaling lymphocytic activation molecule-associated protein controls NKT cell functions
    • Chung B, Aoukaty A, Dutz J, Terhorst C, Tan R, ((2005)) Signaling lymphocytic activation molecule-associated protein controls NKT cell functions. J Immunol 174:: 3153--3157.
    • (2005) J Immunol , vol.174 , pp. 3153-3157
    • Chung, B.1    Aoukaty, A.2    Dutz, J.3    Terhorst, C.4    Tan, R.5
  • 20
    • 20144387328 scopus 로고    scopus 로고
    • Regulation of NKT cell development by SAP, the protein defective in XLP
    • Nichols KE, Hom J, Gong SY, Ganguly A, Ma CS, et al. ((2005)) Regulation of NKT cell development by SAP, the protein defective in XLP. Nat Med 11:: 340--345.
    • (2005) Nat Med , vol.11 , pp. 340-345
    • Nichols, K.E.1    Hom, J.2    Gong, S.Y.3    Ganguly, A.4    Ma, C.S.5
  • 22
    • 0026544338 scopus 로고
    • The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules
    • Wegener AM, Letourneur F, Hoeveler A, Brocker T, Luton F, et al. ((1992)) The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 68:: 83--95.
    • (1992) Cell , vol.68 , pp. 83-95
    • Wegener, A.M.1    Letourneur, F.2    Hoeveler, A.3    Brocker, T.4    Luton, F.5
  • 23
    • 0027399703 scopus 로고
    • Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain
    • Irving BA, Chan AC, Weiss A, ((1993)) Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med 177:: 1093--1103.
    • (1993) J Exp Med , vol.177 , pp. 1093-1103
    • Irving, B.A.1    Chan, A.C.2    Weiss, A.3
  • 24
    • 0026064305 scopus 로고
    • The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways
    • Irving BA, Weiss A, ((1991)) The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell 64:: 891--901.
    • (1991) Cell , vol.64 , pp. 891-901
    • Irving, B.A.1    Weiss, A.2
  • 25
    • 0027185152 scopus 로고
    • T cell activation by clustered tyrosine kinases
    • Kolanus W, Romeo C, Seed B, ((1993)) T cell activation by clustered tyrosine kinases. Cell 74:: 171--183.
    • (1993) Cell , vol.74 , pp. 171-183
    • Kolanus, W.1    Romeo, C.2    Seed, B.3
  • 27
    • 1842631103 scopus 로고    scopus 로고
    • Jurkat T cells and development of the T-cell receptor signalling paradigm
    • Abraham RT, Weiss A, ((2004)) Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat Rev Immunol 4:: 301--308.
    • (2004) Nat Rev Immunol , vol.4 , pp. 301-308
    • Abraham, R.T.1    Weiss, A.2
  • 28
    • 0026483786 scopus 로고
    • ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain
    • Chan AC, Iwashima M, Turck CW, Weiss A, ((1992)) ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell 71:: 649--662.
    • (1992) Cell , vol.71 , pp. 649-662
    • Chan, A.C.1    Iwashima, M.2    Turck, C.W.3    Weiss, A.4
  • 29
    • 23444457121 scopus 로고    scopus 로고
    • Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways
    • Houtman JC, Houghtling RA, Barda-Saad M, Toda Y, Samelson LE, ((2005)) Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways. J Immunol 175:: 2449--2458.
    • (2005) J Immunol , vol.175 , pp. 2449-2458
    • Houtman, J.C.1    Houghtling, R.A.2    Barda-Saad, M.3    Toda, Y.4    Samelson, L.E.5
  • 30
    • 0032498231 scopus 로고    scopus 로고
    • LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
    • Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE, ((1998)) LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 92:: 83--92.
    • (1998) Cell , vol.92 , pp. 83-92
    • Zhang, W.1    Sloan-Lancaster, J.2    Kitchen, J.3    Trible, R.P.4    Samelson, L.E.5
  • 31
    • 0031858649 scopus 로고    scopus 로고
    • Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice
    • Murphy MA, Schnall RG, Venter DJ, Barnett L, Bertoncello I, et al. ((1998)) Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice. Mol Cell Biol 18:: 4872--4882.
    • (1998) Mol Cell Biol , vol.18 , pp. 4872-4882
    • Murphy, M.A.1    Schnall, R.G.2    Venter, D.J.3    Barnett, L.4    Bertoncello, I.5
  • 32
    • 0027193980 scopus 로고
    • Divergent regulation of phosphatidylinositol 3-kinase P85 alpha and P85 beta isoforms upon T cell activation
    • Reif K, Gout I, Waterfield MD, Cantrell DA, ((1993)) Divergent regulation of phosphatidylinositol 3-kinase P85 alpha and P85 beta isoforms upon T cell activation. J Biol Chem 268:: 10780--10788.
    • (1993) J Biol Chem , vol.268 , pp. 10780-10788
    • Reif, K.1    Gout, I.2    Waterfield, M.D.3    Cantrell, D.A.4
  • 33
    • 0025835006 scopus 로고
    • T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1
    • Secrist JP, Karnitz L, Abraham RT, ((1991)) T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1. J Biol Chem 266:: 12135--12139.
    • (1991) J Biol Chem , vol.266 , pp. 12135-12139
    • Secrist, J.P.1    Karnitz, L.2    Abraham, R.T.3
  • 34
    • 0042531873 scopus 로고    scopus 로고
    • SLAM-associated protein deficiency causes imbalanced early signal transduction and blocks downstream activation in T cells from X-linked lymphoproliferative disease patients
    • Sanzone S, Zeyda M, Saemann MD, Soncini M, Holter W, et al. ((2003)) SLAM-associated protein deficiency causes imbalanced early signal transduction and blocks downstream activation in T cells from X-linked lymphoproliferative disease patients. J Biol Chem 278:: 29593--29599.
    • (2003) J Biol Chem , vol.278 , pp. 29593-29599
    • Sanzone, S.1    Zeyda, M.2    Saemann, M.D.3    Soncini, M.4    Holter, W.5
  • 35
    • 0032540957 scopus 로고    scopus 로고
    • A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes
    • Gesbert F, Guenzi C, Bertoglio J, ((1998)) A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes. J Biol Chem 273:: 18273--18281.
    • (1998) J Biol Chem , vol.273 , pp. 18273-18281
    • Gesbert, F.1    Guenzi, C.2    Bertoglio, J.3
  • 36
    • 0027417482 scopus 로고
    • Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events
    • Secrist JP, Burns LA, Karnitz L, Koretzky GA, Abraham RT, ((1993)) Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J Biol Chem 268:: 5886--5893.
    • (1993) J Biol Chem , vol.268 , pp. 5886-5893
    • Secrist, J.P.1    Burns, L.A.2    Karnitz, L.3    Koretzky, G.A.4    Abraham, R.T.5
  • 37
    • 3242749659 scopus 로고    scopus 로고
    • Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)
    • Romero X, Benitez D, March S, Vilella R, Miralpeix M, et al. ((2004)) Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4). Tissue Antigens 64:: 132--144.
    • (2004) Tissue Antigens , vol.64 , pp. 132-144
    • Romero, X.1    Benitez, D.2    March, S.3    Vilella, R.4    Miralpeix, M.5
  • 38
    • 0035451761 scopus 로고    scopus 로고
    • PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models
    • Astoul E, Edmunds C, Cantrell DA, Ward SG, ((2001)) PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models. Trends Immunol 22:: 490--496.
    • (2001) Trends Immunol , vol.22 , pp. 490-496
    • Astoul, E.1    Edmunds, C.2    Cantrell, D.A.3    Ward, S.G.4
  • 39
    • 33646196946 scopus 로고    scopus 로고
    • Regulation of Th2 differentiation and Il4 locus accessibility
    • Ansel KM, Djuretic I, Tanasa B, Rao A, ((2006)) Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 24:: 607--656.
    • (2006) Annu Rev Immunol , vol.24 , pp. 607-656
    • Ansel, K.M.1    Djuretic, I.2    Tanasa, B.3    Rao, A.4
  • 40
    • 0036909586 scopus 로고    scopus 로고
    • The anti-inflammatory sesquiterpene lactone parthenolide suppresses IL-4 gene expression in peripheral blood T
    • Li-Weber M, Giaisi M, Treiber MK, Krammer PH, ((2002)) The anti-inflammatory sesquiterpene lactone parthenolide suppresses IL-4 gene expression in peripheral blood T. Eur J Immunol. 32:: 3587--3597.
    • (2002) Eur J Immunol , vol.32 , pp. 3587-3597
    • Li-Weber, M.1    Giaisi, M.2    Treiber, M.K.3    Krammer, P.H.4
  • 41
    • 82755190049 scopus 로고    scopus 로고
    • SAP-Mediated Inhibition of Diacylglycerol Kinase alpha Regulates TCR-Induced Diacylglycerol Signaling
    • Baldanzi G, Pighini A, Bettio V, Rainero E, Traini S, et al. ((2011)) SAP-Mediated Inhibition of Diacylglycerol Kinase alpha Regulates TCR-Induced Diacylglycerol Signaling. J Immunol 187:: 5941--5951.
    • (2011) J Immunol , vol.187 , pp. 5941-5951
    • Baldanzi, G.1    Pighini, A.2    Bettio, V.3    Rainero, E.4    Traini, S.5
  • 42
    • 0035451092 scopus 로고    scopus 로고
    • Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome
    • Nakamura H, Zarycki J, Sullivan JL, Jung JU, ((2001)) Abnormal T cell receptor signal transduction of CD4 Th cells in X-linked lymphoproliferative syndrome. J Immunol 167:: 2657--2665.
    • (2001) J Immunol , vol.167 , pp. 2657-2665
    • Nakamura, H.1    Zarycki, J.2    Sullivan, J.L.3    Jung, J.U.4
  • 43
    • 0033118716 scopus 로고    scopus 로고
    • Crippling of CD3-zeta ITAMs does not impair T cell receptor signaling
    • Ardouin L, Boyer C, Gillet A, Trucy J, Bernard AM, et al. ((1999)) Crippling of CD3-zeta ITAMs does not impair T cell receptor signaling. Immunity 10:: 409--420.
    • (1999) Immunity , vol.10 , pp. 409-420
    • Ardouin, L.1    Boyer, C.2    Gillet, A.3    Trucy, J.4    Bernard, A.M.5
  • 44
    • 18244395893 scopus 로고    scopus 로고
    • A"three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome
    • Hwang PM, Li C, Morra M, Lillywhite J, Muhandiram DR, et al. ((2002)) A"three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome. Embo J 21:: 314--323.
    • (2002) Embo J , vol.21 , pp. 314-323
    • Hwang, P.M.1    Li, C.2    Morra, M.3    Lillywhite, J.4    Muhandiram, D.R.5
  • 45
    • 0033518296 scopus 로고    scopus 로고
    • Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A
    • Li SC, Gish G, Yang D, Coffey AJ, Forman-Kay JD, et al. ((1999)) Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A. Curr Biol 9:: 1355--1362.
    • (1999) Curr Biol , vol.9 , pp. 1355-1362
    • Li, S.C.1    Gish, G.2    Yang, D.3    Coffey, A.J.4    Forman-Kay, J.D.5
  • 46
    • 0025942245 scopus 로고
    • The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein
    • Chan AC, Irving BA, Fraser JD, Weiss A, ((1991)) The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proc Natl Acad Sci U S A 88:: 9166--9170.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 9166-9170
    • Chan, A.C.1    Irving, B.A.2    Fraser, J.D.3    Weiss, A.4
  • 48
    • 78649815100 scopus 로고    scopus 로고
    • The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms
    • Waterman PM, Cambier JC, ((2010)) The conundrum of inhibitory signaling by ITAM-containing immunoreceptors: potential molecular mechanisms. FEBS Lett 584:: 4878--4882.
    • (2010) FEBS Lett , vol.584 , pp. 4878-4882
    • Waterman, P.M.1    Cambier, J.C.2
  • 49
    • 0032476736 scopus 로고    scopus 로고
    • Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling
    • Haughn L, Leung B, Boise L, Veillette A, Thompson C, et al. ((1998)) Interleukin 2-mediated uncoupling of T cell receptor alpha/beta from CD3 signaling. J Exp Med 188:: 1575--1586.
    • (1998) J Exp Med , vol.188 , pp. 1575-1586
    • Haughn, L.1    Leung, B.2    Boise, L.3    Veillette, A.4    Thompson, C.5
  • 50
    • 70349678683 scopus 로고    scopus 로고
    • Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency
    • Snow AL, Marsh RA, Krummey SM, Roehrs P, Young LR, et al. ((2009)) Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. J Clin Invest 119:: 2976--2989.
    • (2009) J Clin Invest , vol.119 , pp. 2976-2989
    • Snow, A.L.1    Marsh, R.A.2    Krummey, S.M.3    Roehrs, P.4    Young, L.R.5
  • 51
    • 79954621871 scopus 로고    scopus 로고
    • 2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis
    • Bida AT, Upshaw Neff JL, Dick CJ, Schoon RA, Brickshawana A, et al. ((2011)) 2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis. Mol Immunol 48:: 1149--1159.
    • (2011) Mol Immunol , vol.48 , pp. 1149-1159
    • Bida, A.T.1    Upshaw Neff, J.L.2    Dick, C.J.3    Schoon, R.A.4    Brickshawana, A.5
  • 52
    • 52149115590 scopus 로고    scopus 로고
    • The X-linked lymphoproliferative syndrome gene product SAP regulates B cell function through the FcγRIIB receptor
    • Li C, Chung B, Tao J, Iosef C, Aoukaty A, et al. ((2008)) The X-linked lymphoproliferative syndrome gene product SAP regulates B cell function through the FcγRIIB receptor. Cellular Signalling 20:: 1960--1967.
    • (2008) Cellular Signalling , vol.20 , pp. 1960-1967
    • Li, C.1    Chung, B.2    Tao, J.3    Iosef, C.4    Aoukaty, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.