Human platelet concentrates: A source of solvent/detergent-treated highly enriched brain-derived neurotrophic factor

Transfusion

Volumn 52, Issue 8, 2012, Pages 1721-1728

  Burnouf, Thierry ^{a,b,c,d,e,f,g}   Kuo, Ya Po ^{a,b,c,d,e,f,g}   Blum, David ^{a,b,c,d,e,f,g}   Burnouf, Sylvie ^{a,b,c,d,e,f,g}   Su, Chen Yao ^{a,b,c,d,e,f,g}  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b HUMAN PROTEIN PROCESS SCIENCES   (France)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d INSERM   (France)

^e UNIV LILLE   (France)

^f LILLE UNIVERSITY HOSPITAL   (France)

^g MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DETERGENT; OIL; PHOSPHATE; SEPHAROSE; SOLVENT; THROMBOCYTE CONCENTRATE; TRITON X 45; TROPOMYOSIN; TROPOMYOSIN RELATED KINASE B; TYLOXAPOL; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FRACTIONATION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; VIRUS INACTIVATION; WESTERN BLOTTING;

ANIMALS; BLOOD PLATELETS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL FRACTIONATION; CHROMATOGRAPHY, GAS; CHROMATOGRAPHY, LIQUID; DETERGENTS; HIPPOCAMPUS; HUMANS; MICE; PLATELET COUNT; PLATELETPHERESIS; RECEPTOR, TRKB; SOLVENTS;

EID: 84865022744     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2011.03494.x     Document Type: Article

References (54)

1. Nagahara AH, Tuszynski MH,. Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov 2011; 10: 209-19.
2. Zacchigna S, Lambrechts D, Carmeliet P,. Neurovascular signalling defects in neurodegeneration. Nat Rev Neurosci 2008; 9: 169-81.
3. Barde YA, Edgar D, Thoenen H,. Purification of a new neurotrophic factor from mammalian brain. EMBO J 1982; 1: 549-53.
4. Gray K, Ellis V,. Activation of pro-BDNF by the pericellular serine protease plasmin. FEBS Lett 2008; 582: 907-10.
5. Pang PT, Teng HK, Zaitsev E, Woo NT, Sakata K, Zhen S, Teng KK, Yung WH, Hempstead BL, Lu B,. Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 2004; 306: 487-91.
6. Yamamoto H, Gurney ME,. Human platelets contain brain-derived neurotrophic factor. J Neurosci 1990; 10: 3469-78.
7. Greenberg ME, Xu B, Lu B, Hempstead BL,. New insights in the biology of BDNF synthesis and release: implications in CNS function. J Neurosci 2009; 29: 12764-7.
8. Matsumoto T, Rauskolb S, Polack M, Klose J, Kolbeck R, Korte M, Barde YA,. Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF. Nat Neurosci 2008; 11: 131-3.
9. Fumagalli F, Molteni R, Calabrese F, Maj PF, Racagni G, Riva MA,. Neurotrophic factors in neurodegenerative disorders: potential for therapy. CNS Drugs 2008; 22: 1005-19.
10. Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S,. New insights into brain BDNF function in normal aging and Alzheimer disease. Brain Res Rev 2008; 59: 201-20.
11. Massa SM, Yang T, Xie Y, Shi J, Bilgen M, Joyce JN, Nehama D, Rajadas J, Longo FM,. Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. J Clin Invest 2010; 120: 1774-85.
12. Shoval G, Weizman A,. The possible role of neurotrophins in the pathogenesis and therapy of schizophrenia. Eur Neuropsychopharmacol 2005; 15: 319-29.
13. Lee BH, Kim YK,. Reduced platelet BDNF level in patients with major depression. Prog Neuropsychopharmacol Biol Psychiatry 2009; 33: 849-53.
14. Angelucci F, Brene S, Mathe AA,. BDNF in schizophrenia, depression and corresponding animal models. Mol Psychiatry 2005; 10: 345-52.
15. Brunoni AR, Lopes M, Fregni F,. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 2008; 11: 1169-80.
16. Schabitz WR, Steigleder T, Cooper-Kuhn CM, Schwab S, Sommer C, Schneider A, Kuhn HG,. Intravenous brain-derived neurotrophic factor enhances poststroke sensorimotor recovery and stimulates neurogenesis. Stroke 2007; 38: 2165-72.
17. Pan WH, Banks WA, Fasold MB, Bluth J, Kastin AJ,. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998; 37: 1553-61.
18. Brasnjevic I, Steinbusch HW, Schmitz C, Martinez-Martinez P,. Delivery of peptide and protein drugs over the blood-brain barrier. Prog Neurobiol 2009; 87: 212-51.
19. Zuccato C, Cattaneo E,. Role of brain-derived neurotrophic factor in Huntington's disease. Prog Neurobiol 2007; 81: 294-330.
20. Nakagawa T, Ogawa Y, Ebihara K, Yamanaka M, Tsuchida A, Taiji M, Noguchi H, Nakao K,. Anti-obesity and anti-diabetic effects of brain-derived neurotrophic factor in rodent models of leptin resistance. Int J Obes Relat Metab Disord 2003; 27: 557-65.
21. Wang C, Godar RJ, Billington CJ, Kotz CM,. Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet. Am J Physiol Regul Integr Comp Physiol 2010; 298: R1320-32.
22. Ribases M, Gratacos M, Fernandez-Aranda F, Bellodi L, Boni C, Anderluh M, Cavallini MC, Cellini E, Di Bella D, Erzegovesi S, Foulon C, Gabrovsek M, Gorwood P, Hebebrand J, Hinney A, Holliday J, Hu X, Karwautz A, Kipman A, Komel R, Nacmias B, Remschmidt H, Ricca V, Sorbi S, Wagner G, Treasure J, Collier DA, Estivill X,. Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations. Hum Mol Genet 2004; 13: 1205-12.
23. Radka SF, Holst PA, Fritsche M, Altar CA,. Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay. Brain Res 1996; 709: 122-301.
24. Fujimura H, Altar CA, Chen R, Nakamura T, Nakahashi T, Kambayashi J, Sun B, Tandon NN,. Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thromb Haemost 2002; 87: 728-34.
25. Nakahashi T, Fujimura H, Altar CA, Li J, Kambayashi J, Tandon NN, Sun B,. Vascular endothelial cells synthesize and secrete brain-derived neurotrophic factor. FEBS Lett 2000; 470: 113-7.
26. Lommatzsch M, Niewerth A, Klotz J, Schulte-Herbruggen O, Zingler C, Schuff-Werner P, Virchow JC,. Platelet and plasma BDNF in lower respiratory tract infections of the adult. Respir Med 2007; 101: 1493-9.
27. Shih DT, Chen JC, Chen WY, Kuo YP, Su CY, Burnouf T,. Expansion of adipose tissue mesenchymal stromal progenitors in serum-free medium supplemented with virally inactivated allogeneic human platelet lysate. Transfusion 2011; 51: 770-8.
28. Burnouf T, Kuo YP, Huang CT, Tseng YH, Lin CT, Su CY,. A virally inactivated platelet-derived growth factor/vascular endothelial growth factor concentrate fractionated from human platelets. Transfusion 2010; 50: 1702-11.
29. Burnouf T, Chang CW, Kuo YP, Wu YW, Tseng YH, Su CY,. A chromatographically purified human TGF-beta1 fraction from virally inactivated platelet lysates. Vox Sang 2011; 101: 215-20.
30. Burnouf T, Tseng YH, Kuo YP, Su CY,. Solvent/detergent treatment of platelet concentrates enhances the release of growth factors. Transfusion 2008; 48: 1090-8.
31. Burnouf T, Goubran HA, Radosevich M, Sayed MA, Gorgy G, El-Ekiaby M,. A process for solvent/detergent treatment of plasma for transfusion at blood centers that use a disposable-bag system. Transfusion 2006; 46: 2100-8.
32. Su CY, Kuo YP, Lin YC, Huang CT, Tseng YH, Burnouf T,. A virally inactivated functional growth factor preparation from human platelet concentrates. Vox Sang 2009; 97: 119-28.
33. Burnouf PA, Juan PK, Su CY, Kuo YP, Chou ML, Su CH, Tseng YH, Lin CT, Burnouf T,. A novel virally inactivated human platelet lysate preparation rich in TGF-beta, EGF and IGF, and depleted of PDGF and VEGF. Biotechnol Appl Biochem 2010; 56: 151-60.
34. Belarbi K, Burnouf S, Fernandez-Gomez FJ, Desmercieres J, Troquier L, Brouillette J, Tsambou L, Grosjean ME, Caillierez R, Demeyer D, Hamdane M, Schindowski K, Blum D, Buee L,. Loss of medial septum cholinergic neurons in THY-Tau22 mouse model: what links with Tau pathology? Curr Alzheimer Res 2011; 8: 633-8.
35. Su CY, Kuo YP, Nieh HL, Tseng YH, Burnouf T,. Quantitative assessment of the kinetics of growth factors release from platelet gel. Transfusion 2008; 48: 2414-20.
36. Maguire PB, Fitzgerald DJ,. Platelet proteomics. J Thromb Haemost 2003; 1: 1593-601.
37. Lommatzsch M, Zingler D, Schuhbaeck K, Schloetcke K, Zingler C, Schuff-Werner P, Virchow JC,. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging 2005; 26: 115-23.
38. Toyooka K, Asama K, Watanabe Y, Muratake T, Takahashi M, Someya T, Nawa H,. Decreased levels of brain-derived neurotrophic factor in serum of chronic schizophrenic patients. Psychiatry Res 2002; 110: 249-57.
39. Rosenfeld RD, Zeni L, Haniu M, Talvenheimo J, Radka SF, Bennett L, Miller JA, Welcher AA,. Purification and identification of brain-derived neurotrophic factor from human serum. Protein Expr Purif 1995; 6: 465-71.
40. Shimizu E, Hashimoto K, Okamura N, Koike K, Komatsu N, Kumakiri C, Nakazato M, Watanabe H, Shinoda N, Okada S, Iyo M,. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 2003; 54: 70-5.
41. Lindsay RM, Thoenen H, Barde YA,. Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor. Dev Biol 1985; 112: 319-28.
42. Burnouf T, Radosevich M,. Reducing the risk of infection from plasma products: specific preventative strategies. Blood Rev 2000; 14: 94-110.
43. Yang ZF, Ho DW, Lau CK, Tam KH, Lam CT, Poon RT, Fan ST,. Platelet activation during tumor development, the potential role of BDNF-TrkB autocrine loop. Biochem Biophys Res Commun 2006; 346: 981-5.
44. Dichtelmuller HO, Biesert L, Fabbrizzi F, Gajardo R, Groner A, von Hoegen I, Jorquera JI, Kempf C, Kreil TR, Pifat D, Osheroff W, Poelsler G,. Robustness of solvent/detergent treatment of plasma derivatives: a data collection from Plasma Protein Therapeutics Association member companies. Transfusion 2009; 49: 1931-43.
45. Burnouf T, Radosevich M,. Nanofiltration of plasma-derived biopharmaceutical products. Haemophilia 2003; 9: 24-37.
46. Rosenthal A, Goeddel DV, Nguyen T, Martin E, Burton LE, Shih A, Laramee GR, Wurm F, Mason A, Nikolics K, Winslow JW,. Primary structure and biological activity of human brain-derived neurotrophic factor. Endocrinology 1991; 129: 1289-94.
47. Wellmer A, Misra VP, Sharief MK, Kopelman PG, Anand P,. A double-blind placebo-controlled clinical trial of recombinant human brain-derived neurotrophic factor (rhBDNF) in diabetic polyneuropathy. J Peripher Nerv Syst 2001; 6: 204-10.
48. de Marco A,. Strategies for successful recombinant expression of disulfide bond-dependent proteins in Escherichia coli. Microb Cell Fact 2009; 8: 26.
49. Burnouf T,. Recombinant plasma proteins. Vox Sang 2011; 100: 68-83.
50. Narhi LO, Rosenfeld R, Talvenheimo J, Prestrelski SJ, Arakawa T, Lary JW, Kolvenbach CG, Hecht R, Boone T, Miller JA, Yphantis DA,. Comparison of the biophysical characteristics of human brain-derived neurotrophic factor, neurotrophin-3, and nerve growth factor. J Biol Chem 1993; 268: 13309-17.
51. Ibanez CF,. Neurotrophic factors: from structure-function studies to designing effective therapeutics. Trends Biotechnol 1995; 13: 217-27.
52. Shimizu N, Fukuzono S, Fujimori K, Park K, Takeshita T, Ishibashi T,. Biological activity of brain-derived neurotrophic factor with mismatched disulfide linkages produced by Escherichia coli. Biosci Biotechnol Biochem 1996; 60: 971-4.
53. Leibrock J, Lottspeich F, Hohn A, Hofer M, Hengerer B, Masiakowski P, Thoenen H, Barde YA,. Molecular cloning and expression of brain-derived neurotrophic factor. Nature 1989; 341: 149-52.
54. Tamura S, Suzuki H, Hirowatari Y, Hatase M, Nagasawa A, Matsuno K, Kobayashi S, Moriyama T,. Release reaction of brain-derived neurotrophic factor (BDNF) through PAR1 activation and its two distinct pools in human platelets. Thromb Res 2011; 128: E55-E61.