메뉴 건너뛰기




Volumn 154, Issue 4, 2008, Pages 1619-1626

When administered to rats in a cold environment, 3,4-methylenedioxymethamphetamine reduces brown adipose tissue thermogenesis and increases tail blood flow: Effects of pretreatment with 5-HT1A and dopamine D2 antagonists

Author keywords

ambient temperature; MDMA; thermoregulation

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SPIPERONE;

EID: 45849097934     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.04.041     Document Type: Article
Times cited : (28)

References (34)
  • 1
    • 0031951628 scopus 로고    scopus 로고
    • Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism
    • Balcioglu A., and Wurtman R.J. Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism. J Pharmacol Exp Ther 284 (1998) 991-997
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 991-997
    • Balcioglu, A.1    Wurtman, R.J.2
  • 2
    • 0035012074 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions
    • Bankson M.G., and Cunningham K.A. 3,4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions. J Pharmacol Exp Ther 297 (2001) 846-852
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 846-852
    • Bankson, M.G.1    Cunningham, K.A.2
  • 3
    • 0345118148 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine 1A receptor activation reduces cutaneous vasoconstriction and fever associated with the acute inflammatory response in rabbits
    • Blessing W.W. 5-Hydroxytryptamine 1A receptor activation reduces cutaneous vasoconstriction and fever associated with the acute inflammatory response in rabbits. Neuroscience 123 (2004) 1-4
    • (2004) Neuroscience , vol.123 , pp. 1-4
    • Blessing, W.W.1
  • 4
    • 33846781341 scopus 로고    scopus 로고
    • Activation of dopamine D2 receptors in the CNS inhibits sympathetic cutaneous vasomotor alerting responses (SCVARs), contributing to clozapine's SCVAR-inhibiting action
    • Blessing W.W., and Ootsuka Y. Activation of dopamine D2 receptors in the CNS inhibits sympathetic cutaneous vasomotor alerting responses (SCVARs), contributing to clozapine's SCVAR-inhibiting action. Prog Neuropsychopharmacol Biol Psychiatry 31 (2007) 328-336
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 328-336
    • Blessing, W.W.1    Ootsuka, Y.2
  • 5
    • 0038043717 scopus 로고    scopus 로고
    • Clozapine reverses hyperthermia and sympathetically mediated cutaneous vasoconstriction induced by 3,4-methylenedioxymethamphetamine (ecstasy) in rabbits and rats
    • Blessing W.W., Seaman B., Pedersen N.P., and Ootsuka Y. Clozapine reverses hyperthermia and sympathetically mediated cutaneous vasoconstriction induced by 3,4-methylenedioxymethamphetamine (ecstasy) in rabbits and rats. J Neurosci 23 (2003) 6385-6391
    • (2003) J Neurosci , vol.23 , pp. 6385-6391
    • Blessing, W.W.1    Seaman, B.2    Pedersen, N.P.3    Ootsuka, Y.4
  • 6
    • 33747414468 scopus 로고    scopus 로고
    • Clozapine reverses increased brown adipose tissue thermogenesis induced by 3,4-methylenedioxymethamphetamine and by cold exposure in conscious rats
    • Blessing W.W., Zilm A., and Ootsuka Y. Clozapine reverses increased brown adipose tissue thermogenesis induced by 3,4-methylenedioxymethamphetamine and by cold exposure in conscious rats. Neuroscience 141 (2006) 2067-2073
    • (2006) Neuroscience , vol.141 , pp. 2067-2073
    • Blessing, W.W.1    Zilm, A.2    Ootsuka, Y.3
  • 7
    • 33751179441 scopus 로고    scopus 로고
    • Interactions between 3,4-methylenedioxymethamphetamine and sigma1 receptors
    • Brammer M.K., Gilmore D.L., and Matsumoto R.R. Interactions between 3,4-methylenedioxymethamphetamine and sigma1 receptors. Eur J Pharmacol 553 (2006) 141-145
    • (2006) Eur J Pharmacol , vol.553 , pp. 141-145
    • Brammer, M.K.1    Gilmore, D.L.2    Matsumoto, R.R.3
  • 8
    • 3142666060 scopus 로고    scopus 로고
    • Brain hyperthermia induced by MDMA (ecstasy): modulation by environmental conditions
    • Brown P.L., and Kiyatkin E.A. Brain hyperthermia induced by MDMA (ecstasy): modulation by environmental conditions. Eur J Neurosci 20 (2004) 51-58
    • (2004) Eur J Neurosci , vol.20 , pp. 51-58
    • Brown, P.L.1    Kiyatkin, E.A.2
  • 9
    • 0347989317 scopus 로고    scopus 로고
    • Brown adipose tissue: function and physiological significance
    • Cannon B., and Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 84 (2004) 277-359
    • (2004) Physiol Rev , vol.84 , pp. 277-359
    • Cannon, B.1    Nedergaard, J.2
  • 10
    • 0028978223 scopus 로고
    • Temperature-dependent effects of [alpha]-adrenergic agonists and antagonists in the cold
    • Carlisle H.J., and Stock M.J. Temperature-dependent effects of [alpha]-adrenergic agonists and antagonists in the cold. Pharmacol Biochem Behav 51 (1995) 263-270
    • (1995) Pharmacol Biochem Behav , vol.51 , pp. 263-270
    • Carlisle, H.J.1    Stock, M.J.2
  • 11
    • 0028335838 scopus 로고
    • Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats
    • Dafters R.I. Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") in rats. Psychopharmacology 114 (1994) 505-508
    • (1994) Psychopharmacology , vol.114 , pp. 505-508
    • Dafters, R.I.1
  • 13
    • 0023154544 scopus 로고
    • The effects of selective dopamine receptor agonists and antagonists on body temperature in rats
    • Faunt J.E., and Crocker A.D. The effects of selective dopamine receptor agonists and antagonists on body temperature in rats. Eur J Pharmacol 133 (1987) 243-247
    • (1987) Eur J Pharmacol , vol.133 , pp. 243-247
    • Faunt, J.E.1    Crocker, A.D.2
  • 14
    • 30544451258 scopus 로고    scopus 로고
    • Studies on the effect of MDMA ("ecstasy") on the body temperature of rats housed at different ambient room temperatures
    • Green A.R., O'Shea E., Saadat K.S., Elliott J.M., and Colado M.I. Studies on the effect of MDMA ("ecstasy") on the body temperature of rats housed at different ambient room temperatures. Br J Pharmacol 146 (2005) 306-312
    • (2005) Br J Pharmacol , vol.146 , pp. 306-312
    • Green, A.R.1    O'Shea, E.2    Saadat, K.S.3    Elliott, J.M.4    Colado, M.I.5
  • 15
    • 44649173724 scopus 로고    scopus 로고
    • Actions of 3,4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons
    • doi:10.1016/j.pbb.2007.10.003
    • Gudelsky G.A., and Yamamoto B.K. Actions of 3,4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons. Pharmacol Biochem Behav (2007) doi:10.1016/j.pbb.2007.10.003
    • (2007) Pharmacol Biochem Behav
    • Gudelsky, G.A.1    Yamamoto, B.K.2
  • 17
    • 0031779196 scopus 로고    scopus 로고
    • Neuronal networks controlling thermoregulatory effectors
    • Kanosue K., Hosono T., Zhang Y.H., and Chen X.M. Neuronal networks controlling thermoregulatory effectors. Prog Brain Res 115 (1998) 49-62
    • (1998) Prog Brain Res , vol.115 , pp. 49-62
    • Kanosue, K.1    Hosono, T.2    Zhang, Y.H.3    Chen, X.M.4
  • 18
    • 0023743162 scopus 로고
    • Novel antipsychotic drugs share high affinity for sigma receptors
    • Largent B.L., Wikstrom H., Snowman A.M., and Snyder S.H. Novel antipsychotic drugs share high affinity for sigma receptors. Eur J Pharmacol 155 (1988) 345-347
    • (1988) Eur J Pharmacol , vol.155 , pp. 345-347
    • Largent, B.L.1    Wikstrom, H.2    Snowman, A.M.3    Snyder, S.H.4
  • 19
    • 0032125256 scopus 로고    scopus 로고
    • Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat
    • Malberg J.E., and Seiden L.S. Small changes in ambient temperature cause large changes in 3,4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body temperature in the rat. J Neurosci 18 (1998) 5086-5094
    • (1998) J Neurosci , vol.18 , pp. 5086-5094
    • Malberg, J.E.1    Seiden, L.S.2
  • 21
    • 1942455273 scopus 로고    scopus 로고
    • Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesis
    • Morrison S.F. Activation of 5-HT1A receptors in raphe pallidus inhibits leptin-evoked increases in brown adipose tissue thermogenesis. Am J Physiol Regul Integr Comp Physiol 286 (2004) R832-R837
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Morrison, S.F.1
  • 22
    • 0142062038 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine 1A receptors inhibit cold-induced sympathetically mediated cutaneous vasoconstriction in rabbits
    • Ootsuka Y., and Blessing W.W. 5-Hydroxytryptamine 1A receptors inhibit cold-induced sympathetically mediated cutaneous vasoconstriction in rabbits. J Physiol 552 (2003) 303-314
    • (2003) J Physiol , vol.552 , pp. 303-314
    • Ootsuka, Y.1    Blessing, W.W.2
  • 23
    • 15544383342 scopus 로고    scopus 로고
    • Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit
    • Ootsuka Y., and Blessing W.W. Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit. Am J Physiol Regul Integr Comp Physiol 288 (2005) R909-R918
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.288
    • Ootsuka, Y.1    Blessing, W.W.2
  • 24
    • 31944452670 scopus 로고    scopus 로고
    • Thermogenesis in brown adipose tissue: increase by 5-HT2A receptor activation and decrease by 5-HT1A receptor activation in conscious rats
    • Ootsuka Y., and Blessing W.W. Thermogenesis in brown adipose tissue: increase by 5-HT2A receptor activation and decrease by 5-HT1A receptor activation in conscious rats. Neurosci Lett 395 (2006) 170-174
    • (2006) Neurosci Lett , vol.395 , pp. 170-174
    • Ootsuka, Y.1    Blessing, W.W.2
  • 25
    • 0442323510 scopus 로고    scopus 로고
    • Inhibition of rostral medullary raphe neurons prevents cold-induced activity in sympathetic nerves to rat tail and rabbit ear arteries
    • Ootsuka Y., Blessing W.W., and McAllen R.M. Inhibition of rostral medullary raphe neurons prevents cold-induced activity in sympathetic nerves to rat tail and rabbit ear arteries. Neurosci Lett 357 (2004) 58-62
    • (2004) Neurosci Lett , vol.357 , pp. 58-62
    • Ootsuka, Y.1    Blessing, W.W.2    McAllen, R.M.3
  • 26
    • 2942716696 scopus 로고    scopus 로고
    • Spinal 5-HT2A receptors regulate cutaneous sympathetic vasomotor outflow in rabbits and rats: relevance for cutaneous vasoconstriction elicited by MDMA (3,4-methylenedioxymethamphetamine, "ecstasy") and its reversal by clozapine
    • Ootsuka Y., Nalivaiko E., and Blessing W.W. Spinal 5-HT2A receptors regulate cutaneous sympathetic vasomotor outflow in rabbits and rats: relevance for cutaneous vasoconstriction elicited by MDMA (3,4-methylenedioxymethamphetamine, "ecstasy") and its reversal by clozapine. Brain Res 1014 (2004) 34-44
    • (2004) Brain Res , vol.1014 , pp. 34-44
    • Ootsuka, Y.1    Nalivaiko, E.2    Blessing, W.W.3
  • 27
    • 34249871938 scopus 로고    scopus 로고
    • Dopamine D(2) receptor stimulation inhibits cold-initiated thermogenesis in brown adipose tissue in conscious rats
    • Ootsuka Y., Heidbreder C.A., Hagan J.J., and Blessing W.W. Dopamine D(2) receptor stimulation inhibits cold-initiated thermogenesis in brown adipose tissue in conscious rats. Neuroscience 147 (2007) 127-135
    • (2007) Neuroscience , vol.147 , pp. 127-135
    • Ootsuka, Y.1    Heidbreder, C.A.2    Hagan, J.J.3    Blessing, W.W.4
  • 28
    • 25844486509 scopus 로고    scopus 로고
    • Interactive drives from two brain stem premotor nuclei are essential to support rat tail sympathetic activity
    • Ootsuka Y., and McAllen R.M. Interactive drives from two brain stem premotor nuclei are essential to support rat tail sympathetic activity. Am J Physiol Regul Integr Comp Physiol 289 (2005) R1107-R1115
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Ootsuka, Y.1    McAllen, R.M.2
  • 29
    • 33748458681 scopus 로고    scopus 로고
    • Comparison between two rat sympathetic pathways activated in cold-defense
    • Ootsuka Y., and McAllen R.M. Comparison between two rat sympathetic pathways activated in cold-defense. Am J Physiol 291 (2006) R589-R595
    • (2006) Am J Physiol , vol.291
    • Ootsuka, Y.1    McAllen, R.M.2
  • 30
    • 0019793815 scopus 로고
    • Two distinct central serotonin receptors with different physiological functions
    • Peroutka S.J., Lebovitz R.M., and Snyder S.H. Two distinct central serotonin receptors with different physiological functions. Science 212 (1981) 827-829
    • (1981) Science , vol.212 , pp. 827-829
    • Peroutka, S.J.1    Lebovitz, R.M.2    Snyder, S.H.3
  • 32
    • 35549009362 scopus 로고    scopus 로고
    • 3,4-Methylenedioxymethamphetamine- and 8-hydroxy-2-di-n-propylamino-tetralin-induced hypothermia: role and location of 5-hydroxytryptamine 1A receptors
    • Rusyniak D.E., Zaretskaia M.V., Zaretsky D.V., and DiMicco J.A. 3,4-Methylenedioxymethamphetamine- and 8-hydroxy-2-di-n-propylamino-tetralin-induced hypothermia: role and location of 5-hydroxytryptamine 1A receptors. J Pharmacol Exp Ther 323 (2007) 477-487
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 477-487
    • Rusyniak, D.E.1    Zaretskaia, M.V.2    Zaretsky, D.V.3    DiMicco, J.A.4
  • 33
    • 0030700829 scopus 로고    scopus 로고
    • A simple method, using 2-hydroxypropyl-beta-cyclodextrin, of administering alpha-chloralose at room temperature
    • Storer R.J., Butler P., Hoskin K.L., and Goadsby P.J. A simple method, using 2-hydroxypropyl-beta-cyclodextrin, of administering alpha-chloralose at room temperature. J Neurosci Methods 77 (1997) 49-53
    • (1997) J Neurosci Methods , vol.77 , pp. 49-53
    • Storer, R.J.1    Butler, P.2    Hoskin, K.L.3    Goadsby, P.J.4
  • 34
    • 0011190242 scopus 로고
    • 1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs
    • Weber E., Sonders M., Quarum M., McLean S., Pou S., and Keana J.F. 1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs. Proc Natl Acad Sci U S A 83 (1986) 8784-8788
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 8784-8788
    • Weber, E.1    Sonders, M.2    Quarum, M.3    McLean, S.4    Pou, S.5    Keana, J.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.