Adoptive transfer of all-trans-retinal-induced regulatory T cells ameliorates experimental autoimmune arthritis in an interferon-gamma knockout model

Autoimmunity

Volumn 45, Issue 6, 2012, Pages 460-469

  Jeon, Eun Joo ^a   Yoon, Bo Young ^c   Lim, Jung Yeon ^a   Oh, Hye Jwa ^a   Park, Hyun Sil ^a   Park, Min Jung ^a   Lim, Mi Ae ^a   Park, Mi Kyung ^a   Kim, Kyung Woon ^a   Cho, Mi La ^a   Cho, Seok Goo ^a,b  

^a The Catholic University of Korea College of Medicine   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c Inje University College of Medicine   (South Korea)

Author keywords

All trans retinal (retinal); Collagen induced arthritis (CIA); IL 17 producing helper T cells (Th17 cells); inflammation; T regulatory cells (Tregs)

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 6; RETINAL; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; C57BL 6 MOUSE; CD4+ T LYMPHOCYTE; CELL TRANSFER; CONTROLLED STUDY; FEMALE; IMMUNIZATION; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SPLEEN CELL; TH17 CELL;

ADOPTIVE TRANSFER; ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOIMMUNE DISEASES; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; INTERFERON-GAMMA; INTERLEUKIN-17; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RETINALDEHYDE; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84864967278     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2012.682666     Document Type: Article

References (23)

1. Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Reciprocal developmental pathwaysfor the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006;441:235-238.
2. Camps M, Ruckle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Francon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Blockade of PI3Kg suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med 2005;11:936-943.
3. Chu CQ, SwartD, AlcornD, Tocker J, Elkon KB. Interferon-g regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17. Arthritis Rheum 2007;56: 1145-1151.
4. Brand DD, Latham KA, Rosloniec EF. Collagen-induced arthritis. Nature Pro 2007;5:1269-1275.
5. Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4CD25 regulatory T cells. Nat Immunol 2003;4:330-336.
6. Furuzawa-Carballeda J, Vargas-Rojas MI, Cabral AR. Autoimmune inflammation from the Th17 perspective. Autoimmun Rev 2007;6:169-175.
7. Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S. Preferential recruitment of CCR6- expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med 2007; 204:2803-2812.
8. Ichiyama K, Yoshida H, Wakabayashi Y, Chinen T, Saeki K, Nakaya M, Takaesu G, Hori S, Yoshimura A, Kobayashi T.Foxp3 inhibits RORgt-mediated IL-17A mRNA transcription through direct interaction with RORgt. J Biol Chem 2008;283: 17003-17008.
9. Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. The orphan nuclear receptor RORgt directs the differentiation program of proinflammatory IL-17 T helper cells. Cell 2006;126:1121-1133.
10. Kuwabara K, Shudo K, Hori Y. Novel synthetic retinoic acid inhibits rat collagen arthritis and differentially affects serum immunoglobulin subclass levels. FEBS Lett 1996;378: 153-156.
11. Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, Cheroutre H. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007;317: 256-260.
12. Niedbala W, Wei XQ, Cai B, Hueber AJ, Leung BP, McInnes IB, Liew FY. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. Eur J Immunol 2007;37:3021-3029.
13. Nozaki Y, Yamagata T, Sugiyama M, Ikoma S, Kinoshita K, Funauchi M. Anti-inflammatory effect of all-trans-retinoic acid in inflammatory arthritis. Clin Immunol 2006;119: 272-279.
14. Park MK, Park JS, Cho ML, Oh HJ, Heo YJ, Woo YJ, Heo YM, Park MJ, Park HS, Park SH, Kim HY, Min JK. Grape seed proanthocyanidin extract (GSPE) differentially regulates Foxp3() regulatory and IL-17() pathogenic T cell in autoimmune arthritis. Immunol Lett 2011;135:50-58.
15. Perez De Lema G, Lucio-Cazana FJ, Molina A, Luckow B, Schlondorff D. Retinoic acid treatment protects MRL/lprlupus mice from the development of glomerular disease. Kidney Int 2004;66:1018-1028.
16. Racke MK, Burnett D, Pak SH, Albert PS, Cannella B, Raine CS, McFarlin DE, Scott DE. Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course. J Immunol 1995; 154:450-458.
17. Reifen R, Nur T, Ghebermeskel K, Zaiger G, Urizky R, Pines M, Vitamin A. deficiency exacerbates inflammation in a rat model f colitis through activation of nuclear factor-kappaB and collagen formation. J Nutr 2002;132:2743-2747.
18. Reiner SL. evelopment in motion: Helper T cells at work. Cell 2007;129:33-36.
19. Saari JC, Garwin GG, Van Hooser JP, Palczewski K. Reduction of all-trans-retinal limits regeneration of visual pigment in mice. Vision Res 1998;38:1325-1333.
20. Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, Watanabe K, Ito K, Takeshita K, Niki T, Saita N, Nishi N, Yamauchi A, Katoh S,Matsukawa A,Kuchroo V,HirashimaM. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 2008;127:78-88.
21. Trapasso E, Cosco D, Celia C, Fresta M, Paolino D. Retinoids: New use by innovative drug-delivery systems. Expert Opin Drug Deliv 2009;6:465-483.
22. Zhao J, Li R, He J, Shi J, Long L, Li Z. Mucosal administrationof an altered CII263-272 peptide inhibits collagen-induced arthritis by suppression of Th1/Th17 cells and expansion of regulatory T cells. Rheumatol Int 2008;29:9-16.
23. Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, Victora GD, Shen Y, Du J, Rubtsov YP, Rudensky AY, Ziegler SF, Littman DR. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgt function. Nature 2008; 453:236-240.