Mucosal administration of an altered CII263-272 peptide inhibits collagen-induced arthritis by suppression of Th1/Th17 cells and expansion of regulatory T cells

Rheumatology International

Volumn 29, Issue 1, 2008, Pages 9-16

  Zhao, Jinxia ^a   Li, Ru ^a   He, Jing ^a   Shi, Jinxia ^a   Long, Li ^a   Li, Zhanguo ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

Altered peptide; Arthritis, rheumatoid; Collagen induced arthritis; Collagen type II; Interleukin 17; Regulatory T cells

Indexed keywords

COLLAGEN; COLLAGEN TYPE II[263-272]; GAMMA INTERFERON; HLA DR4 ANTIGEN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 17; PEPTIDE DERIVATIVE; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HELPER CELL; HUMORAL IMMUNITY; IMMUNOSUPPRESSIVE TREATMENT; LEWIS RAT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; REGULATORY T LYMPHOCYTE; RHEUMATOID ARTHRITIS; T LYMPHOCYTE ACTIVATION;

ADMINISTRATION, INTRANASAL; ANIMALS; ARTHRITIS, EXPERIMENTAL; CYTOKINES; FEMALE; HINDLIMB; JOINTS; LYMPHOCYTE ACTIVATION; NASAL MUCOSA; PEPTIDE FRAGMENTS; RATS; RATS, INBRED LEW; SEVERITY OF ILLNESS INDEX; SPECIFIC PATHOGEN-FREE ORGANISMS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 53249127057     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00296-008-0634-4     Document Type: Article

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