메뉴 건너뛰기




Volumn 20, Issue 4, 2012, Pages 195-205

Therapeutic effect of withania somnifera on pristane-induced model of SLE

Author keywords

Autoantibodies; Immune complexes; Immunomodulatory properties; Inflammation; Pristane induced model of SLE; Withania somnifera

Indexed keywords

INTERLEUKIN 6; NITRIC OXIDE; PRISTANE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; WITHANIA SOMNIFERA EXTRACT;

EID: 84864927212     PISSN: 09254692     EISSN: 15685608     Source Type: Journal    
DOI: 10.1007/s10787-011-0102-8     Document Type: Article
Times cited : (26)

References (37)
  • 1
    • 77952214542 scopus 로고    scopus 로고
    • Genomic analysis highlights the role of the JAKSTAT signaling in the anti-proliferative effects of dietary flavonoid-'Ashwagandha' in prostate cancer cells
    • Aalinkeel R, Hu Z, Nair BB, Sykes DE, Reynolds JL, Mahajan SD et al (2010) Genomic analysis highlights the role of the JAKSTAT signaling in the anti-proliferative effects of dietary flavonoid-'Ashwagandha' in prostate cancer cells. Evid Based Complement Altern Med 7:177-187
    • (2010) Evid Based Complement Altern Med , vol.7 , pp. 177-187
    • Aalinkeel, R.1    Hu, Z.2    Nair, B.B.3    Sykes, D.E.4    Reynolds, J.L.5    Mahajan, S.D.6
  • 2
    • 0033392878 scopus 로고    scopus 로고
    • Suppressive effect of Withania somnifera root extract on the induction of anti-ovalbumin IgE antibody response in mice
    • Amara S, Kumar SP, Athota RR (1999) Effect Of Withania somnifera root extract on the induction of anti-ovalbumin IgE antibody response in mice. Pharm Biol 37:253-259 (Pubitemid 30035137)
    • (1999) Pharmaceutical Biology , vol.37 , Issue.4 , pp. 253-259
    • Amara, S.1    Kumar, S.P.2    Athota, R.R.3
  • 3
    • 70349591047 scopus 로고    scopus 로고
    • Neuroprotective effects of Withania somnifera dunal.: A possible mechanism
    • Bhatnagar M, Sharma D, Salvi M (2009) Neuroprotective effects of Withania somnifera dunal.: A possible mechanism. Neurochem Res 34:1975-1983
    • (2009) Neurochem Res , vol.34 , pp. 1975-1983
    • Bhatnagar, M.1    Sharma, D.2    Salvi, M.3
  • 4
    • 78149415859 scopus 로고    scopus 로고
    • The influence of traditional herbal formulas on cytokine activity
    • Burns JJ, Zhao L, Taylor EW, Spelman K (2010) The influence of traditional herbal formulas on cytokine activity. Toxicology 278:140-159
    • (2010) Toxicology , vol.278 , pp. 140-159
    • Burns, J.J.1    Zhao, L.2    Taylor, E.W.3    Spelman, K.4
  • 5
    • 79952481036 scopus 로고    scopus 로고
    • Targeting B cells for the treatment of SLE: The beginning of the end or the end of the beginning?
    • Calero I, Sanz I (2010) Targeting B cells for the treatment of SLE: the beginning of the end or the end of the beginning? Discov Med 10:416-424
    • (2010) Discov Med , vol.10 , pp. 416-424
    • Calero, I.1    Sanz, I.2
  • 8
    • 4944239830 scopus 로고    scopus 로고
    • A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees
    • DOI 10.1097/01.rhu.0000138087.47382.6d
    • Chopra A, Lavin P, Patwardhan B, Chitre D (2004) A 32 week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees. J Clin Rheumatol 10:236-245 (Pubitemid 39332161)
    • (2004) Journal of Clinical Rheumatology , vol.10 , Issue.5 , pp. 236-245
    • Chopra, A.1    Lavin, P.2    Patwardhan, B.3    Chitre, D.4
  • 10
    • 0032756875 scopus 로고    scopus 로고
    • Effect of withania somnifera on cytokine production in normal and cyclophosphamide treated mice
    • Davis L, Kuttan G (1999) Effect of Withania somnifera on cytokine production in normal and cyclophosphamide treated mice. Immunopharmacol Immunotoxicol 21:695-703
    • (1999) Immunopharmacol Immunotoxicol , vol.21 , pp. 695-703
    • Davis, L.1    Kuttan, G.2
  • 12
    • 0030883103 scopus 로고    scopus 로고
    • Effect of some Indian herbs on macrophage functions in ochratoxin A treated mice
    • DOI 10.1016/S0378-8741(97)00072-X, PII S037887419700072X
    • Dhuley JN (1997) Effect of some Indian herbs on macrophage functions in ochratoxin A treated mice. J Ethnopharmacol 58:15-20 (Pubitemid 27406182)
    • (1997) Journal of Ethnopharmacology , vol.58 , Issue.1 , pp. 15-20
    • Dhuley, J.N.1
  • 13
    • 0032925391 scopus 로고    scopus 로고
    • Correlation of serum measures of nitric oxide production with lupus disease activity
    • Gilkeson G, Cannon C, Oates J, Reilly C, Goldman D, Petri M (1999) Correlation of serum measures of nitric oxide production with lupus disease activity. J Rheumatol 26:318-324 (Pubitemid 29066735)
    • (1999) Journal of Rheumatology , vol.26 , Issue.2 , pp. 318-324
    • Gilkeson, G.1    Cannon, C.2    Oates, J.3    Reilly, C.4    Goldman, D.5    Petri, M.6
  • 14
    • 50949105388 scopus 로고    scopus 로고
    • Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?
    • Griffiths HR (2008) Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease? Autoimmun Rev 7:544-549
    • (2008) Autoimmun Rev , vol.7 , pp. 544-549
    • Griffiths, H.R.1
  • 15
    • 77956844800 scopus 로고    scopus 로고
    • Therapeutic strategies for SLE involving cytokines: Mechanism-oriented therapies especially ifn-c targeting gene therapy
    • doi:10.1155/2010/461641
    • Hayashi T (2010) Therapeutic strategies for SLE involving cytokines: mechanism-oriented therapies especially IFN-c targeting gene therapy. J Biomed Biotechnol 2010:19. doi:10.1155/2010/ 461641
    • (2010) J Biomed Biotechnol , vol.2010 , Issue.19
    • Hayashi, T.1
  • 16
    • 68549128495 scopus 로고    scopus 로고
    • In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012
    • Kielland A, Blom T, Nandakumar KS, Holmdahl R, Blomhoff R, Carlsen H (2009) In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med 47:760-766
    • (2009) Free Radic Biol Med , vol.47 , pp. 760-766
    • Kielland, A.1    Blom, T.2    Nandakumar, K.S.3    Holmdahl, R.4    Blomhoff, R.5    Carlsen, H.6
  • 17
    • 0025766095 scopus 로고
    • Treatment of osteoarthritis with a herbomineral formulation: A double-blind, placebo-controlled, cross-over study
    • Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B (1991) Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 33:91-95
    • (1991) J Ethnopharmacol , vol.33 , pp. 91-95
    • Kulkarni, R.R.1    Patki, P.S.2    Jog, V.P.3    Gandage, S.G.4    Patwardhan, B.5
  • 19
    • 34848858255 scopus 로고    scopus 로고
    • Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine
    • DOI 10.1007/s10495-007-0129-x
    • Malik F, Kumar A, Bhushan S, Khan S, Bhatia A, Suri KA et al (2007a) Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine. Apoptosis 12:2115-2133 (Pubitemid 47498235)
    • (2007) Apoptosis , vol.12 , Issue.11 , pp. 2115-2133
    • Malik, F.1    Kumar, A.2    Bhushan, S.3    Khan, S.4    Bhatia, A.5    Suri, K.A.6    Qazi, G.N.7    Singh, J.8
  • 20
    • 33947148594 scopus 로고    scopus 로고
    • A standardized root extract of Withania somnifera and its major constituent withanolide-A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice
    • DOI 10.1016/j.lfs.2007.01.029, PII S0024320507000665
    • Malik F, Singh J, Khajuria A, Suri KA, Satti NK, Singh S, Kaul MK, Kumar A, Bhatia A, Qazi GN (2007b) A standardized root extract of Withania somnifera and its major constituent withanolide- A elicit humoral and cell-mediated immune responses by up regulation of Th1-dominant polarization in BALB/c mice. Life Sci 80:1525-1538 (Pubitemid 46399749)
    • (2007) Life Sciences , vol.80 , Issue.16 , pp. 1525-1538
    • Malik, F.1    Singh, J.2    Khajuria, A.3    Suri, K.A.4    Satti, N.K.5    Singh, S.6    Kaul, M.K.7    Kumar, A.8    Bhatia, A.9    Qazi, G.N.10
  • 21
    • 0033845752 scopus 로고    scopus 로고
    • Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): A review
    • Mishra LC, Singh BB, Dagenais S (2000) Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): a review. Altern Med Rev 5:334-346 (Pubitemid 30660827)
    • (2000) Alternative Medicine Review , vol.5 , Issue.4 , pp. 334-346
    • Mishra, L.-C.1    Singh, B.B.2    Dagenais, S.3
  • 23
    • 33646787097 scopus 로고    scopus 로고
    • Immunomodulatory role of Withania somnifera root powder on experimental induced inflammation: An in vivo and in vitro study
    • DOI 10.1016/j.vph.2006.01.015, PII S1537189106000747
    • Rasool M, Varalakshmi P (2006) Immunomodulatory role of Withania somnifera root powder on experimental induced inflammation: an in vivo&in vitro study. Vascul Pharmacol 44:406-410 (Pubitemid 43766670)
    • (2006) Vascular Pharmacology , vol.44 , Issue.6 , pp. 406-410
    • Rasool, M.1    Varalakshmi, P.2
  • 24
    • 68949183471 scopus 로고    scopus 로고
    • Induction of autoimmunity by pristane and other naturally occurring hydrocarbons
    • Reeves WH, Lee PY, Weinstein JS, Minoru Satoh, Lu L (2009) Induction of autoimmunity by pristane and other naturally occurring hydrocarbons. Trends Immunol 30:455-464
    • (2009) Trends Immunol , vol.30 , pp. 455-464
    • Reeves, W.H.1    Lee, P.Y.2    Weinstein, J.S.3    Satoh, M.4    Lu, L.5
  • 28
    • 0027938860 scopus 로고
    • Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane
    • DOI 10.1084/jem.180.6.2341
    • Satoh M, Reeves WH (1994) Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane. J Exp Med 180:2341-2346 (Pubitemid 24351616)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.6 , pp. 2341-2346
    • Satoh, M.1    Reeves, W.H.2
  • 29
    • 0028845353 scopus 로고
    • Anti-nuclear antibody production and immune-complex glomerulonephritis in balb/c mice treated with pristane
    • Satoh M, Kumar A, Kanwar YS, Reeves WH (1995) Anti-nuclear antibody production and immune-complex glomerulonephritis in BALB/c mice treated with pristane. Proc Natl Acad Sci USA 92:10934-10938
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 10934-10938
    • Satoh, M.1    Kumar, A.2    Kanwar, Y.S.3    Reeves, W.H.4
  • 31
    • 0031729854 scopus 로고    scopus 로고
    • Role of nitric oxide in inflammation and tissue injury during endotoxemia and hemorrhagic shock
    • Shah NS, Billiar TR (1998) Role of nitric oxide in Inflammation and tissue injury during endotoxemia and hemorrhagic shock. Environ Health Perspect 106:1139-1143 (Pubitemid 28554518)
    • (1998) Environmental Health Perspectives , vol.106 , Issue.SUPPL. 5 , pp. 1139-1143
    • Shah, N.S.1    Billiar, T.R.2
  • 32
    • 79959343592 scopus 로고    scopus 로고
    • Withania somnifera improves semen quality by combating oxidative stress and cell death and improving essential metal concentrations
    • (Epub ahead of print)
    • Shukla KK, Mahdi AA, Mishra V, Rajender S, Sankhwar SN, Patel D, Das M (2011) Withania somnifera improves semen quality by combating oxidative stress and cell death and improving essential metal concentrations. Reprod Biomed Online. (Epub ahead of print)
    • (2011) Reprod Biomed Online
    • Shukla, K.K.1    Mahdi, A.A.2    Mishra, V.3    Rajender, S.4    Sankhwar, S.N.5    Patel, D.6    Das, M.7
  • 33
    • 15944404322 scopus 로고    scopus 로고
    • Anti-cytokine therapy in systemic lupus erythematosus
    • DOI 10.1191/0961203305lu2134oa
    • Smolen JS, Steiner G, Aringer M (2005) Anti-cytokine therapy in systemic lupus erythematosus. Lupus 14:189-191 (Pubitemid 40445581)
    • (2005) Lupus , vol.14 , Issue.3 , pp. 189-191
    • Smolen, J.S.1    Steiner, G.2    Aringer, M.3
  • 35
    • 67049162417 scopus 로고    scopus 로고
    • Efficacy and safety of infliximab in active Sle: A pilot study
    • Uppal SS, Hayat SJ, Raghupathy R (2009) Efficacy and safety of infliximab in active SLE: a pilot study. Lupus 18:690-697
    • (2009) Lupus , vol.18 , pp. 690-697
    • Uppal, S.S.1    Hayat, S.J.2    Raghupathy, R.3
  • 36
    • 0031684184 scopus 로고    scopus 로고
    • Nitric oxide synthesis is increased in patients with systemic lupus erythematosus
    • DOI 10.1007/s002960050055
    • Wanchu A, Khullar M, Deodhar SD, Bambery P, Sud A (1998) Nitric oxide synthesis is increased in patients with systemic lupus erythematosus. Rheumatol Int 18:41-43 (Pubitemid 28432832)
    • (1998) Rheumatology International , vol.18 , Issue.2 , pp. 41-43
    • Wanchu, A.1    Khullar, M.2    Deodhar, S.D.3    Bambery, P.4    Sud, A.5
  • 37
    • 0031689311 scopus 로고    scopus 로고
    • Increased nitric oxide (NO) production by antigen-presenting dendritic cells is responsible for low allogeneic mixed leucocyte reaction (MLR) in primary biliary cirrhosis (PBC)
    • DOI 10.1046/j.1365-2249.1998.00696.x
    • Yamamoto K, Akbar SM, Masumoto T, Onji M (1998) Increased nitric oxide (NO) production by antigen-presenting dendritic cells is responsible for low allogeneic mixed leucocyte reaction (MLR) in primary biliary cirrhosis (PBC). Clin Exp Immunol 114:94-101 (Pubitemid 28442819)
    • (1998) Clinical and Experimental Immunology , vol.114 , Issue.1 , pp. 94-101
    • Yamamoto, K.1    Akbar, F.2    Masumoto, T.3    Onji, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.