Liquid-liquid extraction for recovery of paclitaxel from plant cell culture: Solvent evaluation and use of extractants for partitioning and selectivity

Biotechnology Progress

Volumn 28, Issue 4, 2012, Pages 990-997

  Mcpartland, Timothy J ^a   Patil, Rohan A ^a   Malone, Michael F ^a   Roberts, Susan C ^a  

^a University of Massachusetts   (United States)

Author keywords

Bioseparations; Downstream processing; Paclitaxel; Partition coefficient; Plant cell culture; Selectivity

Indexed keywords

ANTI-CANCER AGENTS; AQUEOUS PHASE; BIO SEPARATION; CULTURE BROTHS; DOWNSTREAM-PROCESSING; ETHYL ACETATES; EXTRACTANTS; HEXAFLUOROBENZENE; LIQUID-LIQUID EXTRACTION; N-HEXANE; PACLITAXEL; PARTITION COEFFICIENT; PLANT CELLS; PLANT-DERIVED PRODUCTS; PURIFICATION PROCESS; SELECTIVITY COEFFICIENT; SEPARATION AND PURIFICATION; SOLVENT MIXTURES; TRIBUTYLPHOSPHATE; TRIOCTYLAMINES;

BIOCHEMISTRY; CATALYST SELECTIVITY; DICHLOROMETHANE; HEXANE; ORGANIC SOLVENTS; PLANT CELL CULTURE; PURIFICATION; RECOVERY; SOLVENTS;

MOLECULAR BIOLOGY;

PACLITAXEL; SOLVENT;

ARTICLE; CELL CULTURE; CHEMISTRY; EVALUATION; INSTRUMENTATION; ISOLATION AND PURIFICATION; KINETICS; LIQUID LIQUID EXTRACTION; METHODOLOGY; PLANT CELL; TAXUS;

CELLS, CULTURED; KINETICS; LIQUID-LIQUID EXTRACTION; PACLITAXEL; PLANT CELLS; SOLVENTS; TAXUS;

EID: 84864831348     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1562     Document Type: Article

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