An improved high-performance liquid chromatography process for the large-scale production of paclitaxel

Separation and Purification Technology

Volumn 76, Issue 3, 2011, Pages 378-384

  Pyo, Sang Hyun ^a,b   Choi, Ho Joon ^a  

^a Samyang Genex   (South Korea)

^b LUND UNIVERSITY   (Sweden)

Author keywords

ODS HPLC; Paclitaxel; Precipitation; Process optimization; Purification; Silica HPLC

Indexed keywords

COLUMN LENGTHS; ECONOMIC ADVANTAGES; HIGH PURITY; LARGE-SCALE PRODUCTION; N-HEXANE; OCTADECYLSILANE; ODS-HPLC; OPTIMIZED PROCESS; PACLITAXEL; PRECIPITATION; PRECIPITATION EFFICIENCY; PROCESS AUTOMATION; PROCESS OPTIMIZATION; PRODUCTION COST; PRODUCTION LEVEL; SAMPLE INJECTION; SOLVENT SYSTEM; STATIONARY PHASIS; TETRAHYDROFURANE;

ACETONE; CHROMATOGRAPHY; DICHLOROMETHANE; HEXANE; LIQUIDS; METHANOL; OPTIMIZATION; ORGANIC SOLVENTS; PROCESS CONTROL; PURIFICATION; SILICA;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 78650522767     PISSN: 13835866     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seppur.2010.11.009     Document Type: Article

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