Viability of freeze dried microencapsulated human retinal pigment epithelial cells

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 2, 2012, Pages 520-526

  Wikström, Jonna ^a,b   Elomaa, Matti ^b   Nevala, Laura ^a   Räikkönen, Johanna ^b   Heljo, Petteri ^a   Urtti, Arto ^a   Yliperttula, Marjo ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Alginate; Cell microcapsulation; Cell therapy; Freeze drying; Retinal pigment epithelial cells; Trehalose

Indexed keywords

ALGINIC ACID; GLYCEROL; POLYCATION; TREHALOSE;

ARTICLE; CELL SHAPE; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; FREEZE DRYING; HUMAN; HUMAN CELL; MICROENCAPSULATION; OXYGEN CONSUMPTION; PIGMENT EPITHELIUM; PRESERVATION; PRIORITY JOURNAL; PRODUCT DEVELOPMENT; SCANNING ELECTRON MICROSCOPY;

ALGINATES; CELL LINE; CELL SURVIVAL; CRYOPRESERVATION; EPITHELIAL CELLS; FREEZE DRYING; GLYCEROL; HUMANS; MICROSCOPY, ELECTRON, SCANNING; OXYGEN CONSUMPTION; POLYLYSINE; RETINAL PIGMENT EPITHELIUM; TREHALOSE;

EID: 84864826429     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.06.014     Document Type: Article

References (39)

1. S.D. Allison, B. Chang, T.W. Randolph, and J.F. Carpenter Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding Arch. Biochem. Biophys. 365 1999 289 298
2. K. Bae, J. Yoon, and T. Park Fabrication of hyaluronic acid hydrogel beads for cell encapsulation Biotechnol. Prog. 22 2006 297 302
3. J. Bloch, A.C. Bachoud-Levi, N. Deglon, J.P. Lefaucher, L. Winkel, S. Palfi, J.P. Nguyen, C. Bourdet, V. Gaura, P. Remy, P. Brugieres, M.F. Boisse, S. Baudic, P. Cesaro, P. Hantrave, P. Aebischer, and M. Peschanski Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study Hum. Gene Ther. 15 2004 968 975
4. T.M.S. Chang Foreword W.M. Kühtreiber, R.P. Lanza, W.L. Chick, Tissue Engineering, Cell Encapsulation Technology and Therapeutics 1999 Birchäuser Boston, 1999 11 12
5. P. Cirone, J. Bourgeois, F. Shen, and P. Chang Combined immunotherapy and antiangiogenic therapy of cancer with microencapsulated cells Hum. Gene Ther. 15 2004 945 959
6. J.H. Crowe, and L.M. Crowe Preservation of mammalian cells - learning nature's tricks Nature Biotechnol. 18 2000 145 146
7. L. Crowe, R. Mouradian, J. Crowe, S. Jackson, and C. Womersley Effects of carbohydrates on membrane stability at low water activities Biochim. Biophys. Acta 769 1984 141 150
8. J.H. Crowe, F. Tablin, W.F. Wolkers, K. Gousset, N.M. Tsvetkova, and J. Ricker Stabilization of membranes in human platelets freeze-dried with trehalose Chem. Phys. Lipids 122 2003 41 52
9. P. de Vos, C.G. Hoogmoed, and H.J. Busscher Chemistry and biocompatibility of alginate-PLL capsules for immunoprotection of mammalian cells J. Biomed. Mater. Res. 60 2002 252 259
10. A. Elbein, Y. Pan, I. Pastuszak, and D. Carroll New insights on trehalose: a multi-functional molecule Glycobiology 13 2003 17 27
11. R.B. Elliott, L. Escobar, P.L.J. Tan, M. Muzina, S. Zwain, and C. Buchanan Live encap-sulated porcine islets from a type 1 diabetic patient 9.5 years after xenotransplantation Xenotransplantation 14 2007 157 161
12. S. Gordon, S. Oppenheimer, A. Mackay, J. Brunnabend, I. Puhlev, and F. Levine Recovery of human mesenchymal stem cells following dehydration and rehydration Cryobiology 43 2001 182
13. M. Hirabayashi, M. Kato, J. Ito, and S. Hochi Viable rat offspring derived from oocytes intracytoplasmically injected with freeze-dried sperm heads Zygote 13 2005 79 85
14. H. Hui, L. Baolin, H. Zezhao, L. Chuan, and W. Zhengzheng Front. Energy Power Eng. 1 2007 120 124
15. T. Joki, M. Machluf, A. Atala, J. Zhu, N.T. Seyfried, I.F. Dunn, T. Abe, R.S. Carroll, and P.M. Black Continuous release of endostatin from microencapsulated engineered cells for tumor therapy Nature Biotech. 19 2001 35 39
16. L. Kontturi, M. Yliperttula, P. Toivainen, A. Määttä, A.M. Määttä, and A. Urtti A laboratory scale device for straightforward production of small uniform sized cell microcapsules with long-term cell viability J. Control. Rel. 152 2011 136 141
17. S.B. Leslie, E. Israeli, B. Lighthart, J.H. Crowe, and L.M. Crowe Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying Appl. Environ. Microbiol. 61 1995 3592 3597
18. F. Lim, and A.M. Sun Microencapsulated islets as bioartificial endocrine pancreas Science 210 1980 908 910
19. X.H. Liu, A. Aksan, M. Menze, S. Hand, and M. Toner Trehalose loading through the mitochondrial permeability transition pore enhances desiccation tolerance in rat liver mitochondria Biochim. Biophys. Acta 1717 2005 21 26
20. M. Löhr, A. Hoffmeyer, J.C. Kröger, M. Freund, J. Hain, A. Holle, P. Karle, W. Knöfel, S. Liebe, P. Müller, H. Nizze, M. Renner, R. Saller, T. Wagner, K. Hauenstein, and B. Günzburg Salmons Microencapsulated cell-mediated treatment of inoperable pancreatic carcinoma Lancet 357 2001 1591 1592
21. P. Matejschuk, K. Malik, C. Duru, and A. Bristow Freeze drying of biologicals: process development to ensure biostability Am. Pharmaceut. Rev. 2009 54 58
22. T. Matsuo Trehalose protects cornel epithelial cells from death by drying Br. J. Ophthalmol. 85 2001 610 612
23. M. Ming, X. Li, X. Fan, D. Yang, L. Li, S. Chen, Q. Gu, and W. Le Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease J. Translat. Med. 7 2009 53
24. T. Read, D. Sorensen, R. Mahesparan, P. Enger, R. Timpl, B. Olsen, M. Hjelstuen, O. Haraldseth, and R. Bjerkvig Local endostatin treatment of gliomas administered by microencapsulated producer cells Nature Biotechnol. 19 2001 29 34
25. A. Rudolph, and J. Crowe Membrane stabilization during freezing: the role of two natural cryoprotectants, trehalose and proline Cryobiology 22 1985 367 377
26. G. Satpathy, Z. Török, R. Bali, D. Dwyre, E. Little, N. Walker, F. Tablin, J. Crowe, and N. Tsvetkova Loading red blood cells with trehalose: a step towards biostabilization Cryobiology 49 2004 123 136
27. P.A. Sieving, R.C. Caruso, W. Tao, H.R. Coleman, D.J.S. Thompson, K.R. Fullmer, and R.A. Bush Ciliary neurotrophic factor (CNTF) for human retinal degeneration: phase I trial of CNTF delivery by encapsulated cell intraocular implants PNAS 103 2006 3896 3901
28. N.P. Stover, R.A.E. Bakay, T. Subramanian, C.D. Raiser, M.L. Cornfeldt, A.W. Schweikert, R.C. Allen, and R.L. Watts Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinson disease Arch. Neurol. 62 2005 1833 1837
29. B. Strand, L. Byan, P. Veld, B. Kulseng, A. Rokstad, G. Skjk-Braek, and T. Espevik Poly-l-lysine induces fibrosis on alginate microcapsules via the induction of cytokines Cell Transplantat. 10 2001 263 275
30. W. Sun, A. Leopold, and L. Crowe Stability of dry liposomes in sugar glasses Biophys. J. 70 1996 1769 1776
31. E. Trappler Lyophilization equipment H. Costantino, M. Pikal, Lyophilization of Pharmaceuticals 2004 AAPS
32. T. Wakayama, and R. Yanagimachi Development of normal mice from oocytes injected with freeze-dried spermatozoa Nature Biotechnol. 16 1998 639 641
33. W. Wang Lyophilization and development of solid protein pharmaceuticals Int. J. Pharmaceut. 203 2000 1 60
34. J. Wikström, M. Elomaa, H. Syväjärvi, J. Kuokkanen, P. Honkakoski, and A. Urtti Microencapsulation of retinal pigment epithelial cell line for cell therapy Biomaterials 29 2008 869 876
35. J. Wikström, H. Syväjärvi, A. Urtti, and M. Yliperttula Kinetic simulation model of protein secretion and accumulation in the cell microcapsules J. Gene Med. 10 2008 575 582
36. J. Wilson, W. Cui, and E. Chaikof Layer-by-layer assembly of a conformal nanothin PEG coating for intraportal islet transplantation Nano Lett. 8 2008 1940 1948
37. W.F. Wolkers, N.J. Walker, F. Tablin, and J.H. Crowe Human platelets loaded with trehalose survive freeze-drying Cryobiology 42 2001 79 87
38. H.H. Xiao, T.C. Hua, J. Li, X.L. Gu, X. Wang, Z.J. Wu, L.R. Meng, Q.R. Gao, J. Chen, and Z.P. Gong Freeze-drying of mononuclear cells and whole blood of human cord blood CryoLett. 25 2004 111 120
39. H. Zhang, J. Zhu, W. Wang, Y. Wei, and S. Hu Transplantation of micro-encapsulated genetically modified xenogeneic cells augments angiogenesis and improves heart function Gene Ther. 15 2008 40 48