Trehalose protects corneal epithelial cells from death by drying

British Journal of Ophthalmology

Volumn 85, Issue 5, 2001, Pages 610-612

  Matsuo, T ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL TEAR; EYE DROPS; FLUORESCENT DYE; HYALEIN; HYALURONIC ACID; HYDROXYETHYLCELLULOSE; MALTOSE; MYTEAR; SODIUM CHLORIDE; SOFT SANTEAR; TREHALOSE; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CORNEA EPITHELIUM; DESICCATION; DRUG MECHANISM; DRY EYE; EPITHELIUM CELL; HUMAN; HUMAN CELL; KERATOCONJUNCTIVITIS SICCA; LACRIMAL FLUID; PRIORITY JOURNAL;

CELL SURVIVAL; CELLS, CULTURED; DESICCATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRY EYE SYNDROMES; EPITHELIUM, CORNEAL; FLUORESCENT DYES; HUMANS; MALTOSE; OPHTHALMIC SOLUTIONS; STATISTICS, NONPARAMETRIC; TREHALOSE;

EID: 0035036160     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.85.5.610     Document Type: Article

References (9)

1. The epidemiology of dry eye in Melbourne, Australia
2. Keratoconjunctivitis sicca and the Sjogren syndrome
3. Sodium hyaluronate eyedrops in the treatment of dry eyes
4. Anhydrobiosis
5. Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying
6. Trehalose expression confers desiccation tolerance on human cells
7. Stabilization of dry phospholipid bilayers and proteins by sugars
8. The role of vitrification in anhydrobiosis
9. Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration induced protein unfolding