Acute depletion of plasma membrane phospholipids—dissecting the roles of PtdIns(4)P and PtdIns(4,5)P2

Journal of Chemical Biology

Volumn 5, Issue 4, 2012, Pages 137-139

  Jethwa, Nirmal ^a   Fili, Natali ^b   Larijani, Banafshé ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Phospholipids; PI4P; Plasma membrane; PtdIns(4,5)P2

Indexed keywords

INOSITOL POLYPHOSPHATE 5 PHOSPHATASE; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPID;

CELL MEMBRANE; DEPLETION; ENDOCYTOSIS; ENDOSOME; HUMAN; LIPID COMPOSITION; NONHUMAN; PHOSPHOLIPID MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW;

EID: 84864812990     PISSN: 18646158     EISSN: 18646166     Source Type: Journal    
DOI: 10.1007/s12154-012-0080-3     Document Type: Review

References (13)

1. Balla T, Bondeva T, Várnai P (2000) How accurately can we image inositol lipids in living cells? Trends Pharmacol Sci 21:238-241
2. Chen J, Zheng XF, Brown EJ, Schreiber SL (1995) Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue. PNAS 92:4947-4951
3. Choi J, Chen J, Schreiber SL, Clardy J (1996) Structure of the FKBP12-rapamycin complex interacting with binding domain of human FRAP. Science 273:239-242
4. Dube DH, de Graffenried CL, Kohler JJ (2006) Regulating cell surface glycosylation with a small-molecule switch. Methods Enzymol 415:213-229
5. Fili N, Calleja V, Woscholski R, Parker PJ, Larijani B (2006) Compartmental signal modulation: endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting. Proc Natl Acad Sci U S A 103:15473-15478
6. Hammond GRV, Fischer MJ, Anderson KE, Holdich J, Koteci A, Balla T, and Irvine RF (2012) PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science, in press
7. Hammond GRV, Schiavo G, Irvine RF (2009) Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P2. Biochem J 422:23-35
8. Levskaya A, Weiner OD, Lim WA, Voigt CA (2009) Spatiotemporal control of cell signalling using a light-switchable protein interaction. Nature 461:997-1001
9. Li B, Desai SA, MacCorkle-Chosnek RA, Fan L, Spencer DM (2002) A novel conditional Akt “survival switch” reversibly protects cells from apoptosis. Gene Ther 9:233-244
10. Mootz HD, Blum ES, Tyszkiewicz AB, Muir TW (2003) Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo. J Am Chem Soc 125:10561-10569
11. Muthuswamy SK, Gilman M, Brugge JS (1999) Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo-and heterodimers. Mol Cell Biol 19:6845-6857
12. Schlatter S, Senn C, Fussenegger M (2003) Modulation of translation-initiation in CHO-K1 cells by rapamycin-induced heterodimerization of engineered eIF4G fusion proteins. Biotechnol Bioeng 83:210-225
13. Zhang X, Majerus PW (1998) Phosphatidylinositol signalling reactions. Semin Cell Dev Biol 9:153-160