메뉴 건너뛰기




Volumn 36, Issue 8, 2012, Pages 1848-1856

Neuroconnectivity and valproic acid: The myelin hypothesis

Author keywords

Autism; Cognition; Diffusion imaging; Epilepsy; HDAC inhibitors; Myelination; Neuroplasticity; Valproic acid

Indexed keywords

HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; MYELIN; VALPROIC ACID;

EID: 84864812609     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2012.05.006     Document Type: Review
Times cited : (21)

References (72)
  • 3
    • 36248930380 scopus 로고    scopus 로고
    • Valproate use in children and adolescents with bipolar disorder
    • Azorin J.M., Findling R.L. Valproate use in children and adolescents with bipolar disorder. CNS Drugs 2007, 21:1019-1033.
    • (2007) CNS Drugs , vol.21 , pp. 1019-1033
    • Azorin, J.M.1    Findling, R.L.2
  • 4
    • 79551517312 scopus 로고    scopus 로고
    • Selective toxicity by HDAC3 in neurons: regulation by Akt and GSK3beta
    • Bardai F.H., D'Mello S.R. Selective toxicity by HDAC3 in neurons: regulation by Akt and GSK3beta. Journal of Neuroscience 2011, 31(5):1746-1751.
    • (2011) Journal of Neuroscience , vol.31 , Issue.5 , pp. 1746-1751
    • Bardai, F.H.1    D'Mello, S.R.2
  • 5
    • 0346770038 scopus 로고    scopus 로고
    • Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease
    • Bartzokis G. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiology of Aging 2004, 25(1):5-18.
    • (2004) Neurobiology of Aging , vol.25 , Issue.1 , pp. 5-18
    • Bartzokis, G.1
  • 6
    • 33645292555 scopus 로고    scopus 로고
    • Brain myelination in prevalent neuropsychiatric developmental disorders: primary and comorbid addiction
    • Bartzokis G. Brain myelination in prevalent neuropsychiatric developmental disorders: primary and comorbid addiction. Adolescent Psychiatry 2005, 29:55-96.
    • (2005) Adolescent Psychiatry , vol.29 , pp. 55-96
    • Bartzokis, G.1
  • 7
    • 79959544608 scopus 로고    scopus 로고
    • Neuroglialpharmacology: white matter pathophysiologies and psychiatric treatments
    • Bartzokis G. Neuroglialpharmacology: white matter pathophysiologies and psychiatric treatments. Frontiers in Bioscience 2011, 17:2695L 733.
    • (2011) Frontiers in Bioscience , vol.17
    • Bartzokis, G.1
  • 8
    • 0035021676 scopus 로고    scopus 로고
    • Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study
    • Bartzokis G., Beckson M., Lu P.H., Nuechterlein K.H., et al. Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study. Archives of General Psychiatry 2001, 58(5):461-465.
    • (2001) Archives of General Psychiatry , vol.58 , Issue.5 , pp. 461-465
    • Bartzokis, G.1    Beckson, M.2    Lu, P.H.3    Nuechterlein, K.H.4
  • 9
    • 0037337293 scopus 로고    scopus 로고
    • White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study
    • Bartzokis G., Cummings J.L., Sultzer D., Henderson V.W., Nuechterlein K.H., Mintz J. White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study. Archives of Neurology 2003, 60(3):393-398.
    • (2003) Archives of Neurology , vol.60 , Issue.3 , pp. 393-398
    • Bartzokis, G.1    Cummings, J.L.2    Sultzer, D.3    Henderson, V.W.4    Nuechterlein, K.H.5    Mintz, J.6
  • 10
    • 3042662696 scopus 로고    scopus 로고
    • Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical disconnection in aging and Alzheimer's disease
    • Bartzokis G., Sultzer D., Lu P.H., Nuechterlein K.H., Mintz J., Cummings J. Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical disconnection in aging and Alzheimer's disease. Neurobiology of Aging 2004, 25(7):843-851.
    • (2004) Neurobiology of Aging , vol.25 , Issue.7 , pp. 843-851
    • Bartzokis, G.1    Sultzer, D.2    Lu, P.H.3    Nuechterlein, K.H.4    Mintz, J.5    Cummings, J.6
  • 13
    • 78651491550 scopus 로고    scopus 로고
    • Mapping infant brain myelination with magnetic resonance imaging
    • Deoni S.C., Mercure E., Blasi A., Gasston D., et al. Mapping infant brain myelination with magnetic resonance imaging. Journal of Neuroscience 2011, 31(2):784-791.
    • (2011) Journal of Neuroscience , vol.31 , Issue.2 , pp. 784-791
    • Deoni, S.C.1    Mercure, E.2    Blasi, A.3    Gasston, D.4
  • 14
    • 58149377445 scopus 로고    scopus 로고
    • Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsy
    • Deppe M., Kellinghaus C., Duning T., Möddel G., et al. Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsy. Neurology 2008, 71(24):1981-1985.
    • (2008) Neurology , vol.71 , Issue.24 , pp. 1981-1985
    • Deppe, M.1    Kellinghaus, C.2    Duning, T.3    Möddel, G.4
  • 15
    • 77952875979 scopus 로고    scopus 로고
    • HDAC inhibitors and neurodegeneration: at the edge between protection and damage
    • Dietz K.C., Casaccia P. HDAC inhibitors and neurodegeneration: at the edge between protection and damage. Pharmacological Research 2010, 62(1):11-17.
    • (2010) Pharmacological Research , vol.62 , Issue.1 , pp. 11-17
    • Dietz, K.C.1    Casaccia, P.2
  • 16
    • 3042859183 scopus 로고    scopus 로고
    • The activity of antiepileptic drugs as histone deacetylase inhibitors
    • Eyal S., Yagen B., Sobol E., Altschuler Y., Shmuel M., Bialer M. The activity of antiepileptic drugs as histone deacetylase inhibitors. Epilepsia 2004, 45:737-744.
    • (2004) Epilepsia , vol.45 , pp. 737-744
    • Eyal, S.1    Yagen, B.2    Sobol, E.3    Altschuler, Y.4    Shmuel, M.5    Bialer, M.6
  • 17
    • 77649186564 scopus 로고    scopus 로고
    • Quantitative analysis of motor performance in epilepsy patients treated with valproate
    • Farkas Z., Gulyás S., Molnár R., Szirmai I., Kamondi A. Quantitative analysis of motor performance in epilepsy patients treated with valproate. Seizure 2010, 19(3):173-177.
    • (2010) Seizure , vol.19 , Issue.3 , pp. 173-177
    • Farkas, Z.1    Gulyás, S.2    Molnár, R.3    Szirmai, I.4    Kamondi, A.5
  • 18
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A., Sananbenesi F., Wang X., Dobbin M., et al. Recovery of learning and memory is associated with chromatin remodelling. Nature 2007, 447(7141):178-182.
    • (2007) Nature , vol.447 , Issue.7141 , pp. 178-182
    • Fischer, A.1    Sananbenesi, F.2    Wang, X.3    Dobbin, M.4
  • 20
    • 0001471143 scopus 로고
    • Developmental (myelogenetic) localisation of the cerebral cortex in the human
    • Flechsig P. Developmental (myelogenetic) localisation of the cerebral cortex in the human. Lancet 1901, 158:1027-1030.
    • (1901) Lancet , vol.158 , pp. 1027-1030
    • Flechsig, P.1
  • 22
    • 60049089615 scopus 로고    scopus 로고
    • Temporal and spatial development of axonal maturation and myelination of white matter in the developing brain
    • Gao W., Lin W., Chen Y., Gerig G., Smith J.K., Jewells V., Gilmore J.H. Temporal and spatial development of axonal maturation and myelination of white matter in the developing brain. American Journal of Neuroradiology 2009, 30(2):290-296.
    • (2009) American Journal of Neuroradiology , vol.30 , Issue.2 , pp. 290-296
    • Gao, W.1    Lin, W.2    Chen, Y.3    Gerig, G.4    Smith, J.K.5    Jewells, V.6    Gilmore, J.H.7
  • 25
    • 79955622702 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression in physiological and pathological brain processes
    • Gräff J., Kim D., Dobbin M.M., Tsai L.H. Epigenetic regulation of gene expression in physiological and pathological brain processes. Physiological Reviews 2011, 91:603-649.
    • (2011) Physiological Reviews , vol.91 , pp. 603-649
    • Gräff, J.1    Kim, D.2    Dobbin, M.M.3    Tsai, L.H.4
  • 26
    • 0031931040 scopus 로고    scopus 로고
    • Reversible pseudoatrophy of the brain and mental deterioration associated with valproate treatment
    • Guerrini R., Belmonte A., Canapicchi R., Casalini C., Perucca E. Reversible pseudoatrophy of the brain and mental deterioration associated with valproate treatment. Epilepsia 1998, 39:27-32.
    • (1998) Epilepsia , vol.39 , pp. 27-32
    • Guerrini, R.1    Belmonte, A.2    Canapicchi, R.3    Casalini, C.4    Perucca, E.5
  • 27
    • 81055140107 scopus 로고    scopus 로고
    • Similarities and differences of white matter connectivity and water diffusivity in bipolar I and II disorder
    • Ha T.H., Her J.Y., Kim J.H., Chang J.S., Cho H.S., Ha K. Similarities and differences of white matter connectivity and water diffusivity in bipolar I and II disorder. Neuroscience Letters 2011, 505:150-154.
    • (2011) Neuroscience Letters , vol.505 , pp. 150-154
    • Ha, T.H.1    Her, J.Y.2    Kim, J.H.3    Chang, J.S.4    Cho, H.S.5    Ha, K.6
  • 28
    • 33845610181 scopus 로고    scopus 로고
    • Influence of major antiepileptic drugs on attention, reaction time, and speed of information processing: results from a randomized, double-blind, placebo-controlled withdrawal study of seizure-free epilepsy patients receiving monotherapy
    • Hessen E., Lossius M.I., Reinvang I., Gjerstad L. Influence of major antiepileptic drugs on attention, reaction time, and speed of information processing: results from a randomized, double-blind, placebo-controlled withdrawal study of seizure-free epilepsy patients receiving monotherapy. Epilepsia 2006, 47(12):2038-2045.
    • (2006) Epilepsia , vol.47 , Issue.12 , pp. 2038-2045
    • Hessen, E.1    Lossius, M.I.2    Reinvang, I.3    Gjerstad, L.4
  • 29
    • 3242724333 scopus 로고    scopus 로고
    • The history of valproate in clinical neuroscience
    • Henry T.R. The history of valproate in clinical neuroscience. Psychopharmacology Bulletin 2003, 37:5-16.
    • (2003) Psychopharmacology Bulletin , vol.37 , pp. 5-16
    • Henry, T.R.1
  • 30
    • 0030883534 scopus 로고    scopus 로고
    • Regional differences in synaptogenesis in human cerebral cortex
    • Huttenlocher P.R., Dabholkar A.S. Regional differences in synaptogenesis in human cerebral cortex. Journal of Comparative Neurology 1997, 387(2):167-178.
    • (1997) Journal of Comparative Neurology , vol.387 , Issue.2 , pp. 167-178
    • Huttenlocher, P.R.1    Dabholkar, A.S.2
  • 32
    • 59849120110 scopus 로고    scopus 로고
    • Aging white matter and cognition: differential effects of regional variations in diffusion properties on memory, executive functions, and speed
    • Kennedy K.M., Raz N. Aging white matter and cognition: differential effects of regional variations in diffusion properties on memory, executive functions, and speed. Neuropsychologia 2009, 47(3):916-927.
    • (2009) Neuropsychologia , vol.47 , Issue.3 , pp. 916-927
    • Kennedy, K.M.1    Raz, N.2
  • 33
    • 57049177826 scopus 로고    scopus 로고
    • Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity
    • Kim D., Frank C.L., Dobbin M.M., Tsunemoto R.K., et al. Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron 2008, 60(5):803-817.
    • (2008) Neuron , vol.60 , Issue.5 , pp. 803-817
    • Kim, D.1    Frank, C.L.2    Dobbin, M.M.3    Tsunemoto, R.K.4
  • 36
    • 70049095890 scopus 로고    scopus 로고
    • Correlation of brain white matter diffusion anisotropy and mean diffusivity with reaction time in an oddball task
    • Konrad A., Vucurevic G., Musso F., Stoeter P., Winterer G. Correlation of brain white matter diffusion anisotropy and mean diffusivity with reaction time in an oddball task. Neuropsychobiology 2009, 60(2):55-66.
    • (2009) Neuropsychobiology , vol.60 , Issue.2 , pp. 55-66
    • Konrad, A.1    Vucurevic, G.2    Musso, F.3    Stoeter, P.4    Winterer, G.5
  • 37
    • 0025037655 scopus 로고
    • Cytological and quantitative characteristics of four cerebral commissures in the rhesus monkey
    • Lamantia A.S., Rakic P. Cytological and quantitative characteristics of four cerebral commissures in the rhesus monkey. Journal of Comparative Neurology 1990, 291(4):520-537.
    • (1990) Journal of Comparative Neurology , vol.291 , Issue.4 , pp. 520-537
    • Lamantia, A.S.1    Rakic, P.2
  • 38
    • 80755168381 scopus 로고    scopus 로고
    • Effects of adjunct valproic acid on clinical symptoms and saccadic eye movements in schizophrenia
    • Larrison A.L., Babin S.L., Xing Y., Patel S.S., et al. Effects of adjunct valproic acid on clinical symptoms and saccadic eye movements in schizophrenia. Human Psychopharmacology 2011, 26(7):517-525.
    • (2011) Human Psychopharmacology , vol.26 , Issue.7 , pp. 517-525
    • Larrison, A.L.1    Babin, S.L.2    Xing, Y.3    Patel, S.S.4
  • 39
    • 80053617549 scopus 로고    scopus 로고
    • Autism: a " critical period" disorder?
    • LeBlanc J.J., Fagiolini M. Autism: a " critical period" disorder?. Neural Plasticity 2011, 2011:921680.
    • (2011) Neural Plasticity , vol.2011 , pp. 921680
    • LeBlanc, J.J.1    Fagiolini, M.2
  • 41
    • 39749201011 scopus 로고    scopus 로고
    • Consequences of antiepileptic drug withdrawal: a randomized, double-blind study (Akershus Study)
    • Lossius M.I., Hessen E., Mowinckel P., Stavem K., Erikssen J., Gulbrandsen P., Gjerstad L. Consequences of antiepileptic drug withdrawal: a randomized, double-blind study (Akershus Study). Epilepsia 2008, 49(3):455-463.
    • (2008) Epilepsia , vol.49 , Issue.3 , pp. 455-463
    • Lossius, M.I.1    Hessen, E.2    Mowinckel, P.3    Stavem, K.4    Erikssen, J.5    Gulbrandsen, P.6    Gjerstad, L.7
  • 43
    • 64749112939 scopus 로고    scopus 로고
    • Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs
    • Meador K.J., Baker G.A., Browning N., et al. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. New England Journal of Medicine 2009, 360:1597-1605.
    • (2009) New England Journal of Medicine , vol.360 , pp. 1597-1605
    • Meador, K.J.1    Baker, G.A.2    Browning, N.3
  • 44
    • 70349096650 scopus 로고    scopus 로고
    • Biochemical molecular and epigenetic mechanisms of VPA neuroprotection
    • Monti B., Polazzi E., Contestabile A. Biochemical molecular and epigenetic mechanisms of VPA neuroprotection. Current Molecular Pharmacology 2009, 2:95-109.
    • (2009) Current Molecular Pharmacology , vol.2 , pp. 95-109
    • Monti, B.1    Polazzi, E.2    Contestabile, A.3
  • 48
    • 77952168294 scopus 로고    scopus 로고
    • Altered histone acetylation is associated with age-dependent memory impairment in mice
    • Peleg S., Sananbenesi F., Zovoilis A., Burkhardt S., Bahari-Javan S., et al. Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 2010, 328(5979):753-756.
    • (2010) Science , vol.328 , Issue.5979 , pp. 753-756
    • Peleg, S.1    Sananbenesi, F.2    Zovoilis, A.3    Burkhardt, S.4    Bahari-Javan, S.5
  • 49
    • 0036401554 scopus 로고    scopus 로고
    • Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience
    • Perucca E. Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience. CNS Drugs 2002, 16:695-714.
    • (2002) CNS Drugs , vol.16 , pp. 695-714
    • Perucca, E.1
  • 52
    • 78751635260 scopus 로고    scopus 로고
    • Thalamofrontal neurodevelopment in new-onset pediatric idiopathic generalized epilepsy
    • Pulsipher D.T., Dabbs K., Tuchsherer V., Sheth R.D., Koehn M.A., et al. Thalamofrontal neurodevelopment in new-onset pediatric idiopathic generalized epilepsy. Neurology 2011, 76(1):28-33.
    • (2011) Neurology , vol.76 , Issue.1 , pp. 28-33
    • Pulsipher, D.T.1    Dabbs, K.2    Tuchsherer, V.3    Sheth, R.D.4    Koehn, M.A.5
  • 53
    • 33847150936 scopus 로고    scopus 로고
    • Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity
    • Putignano E., Lonetti G., Cancedda L., Ratto G., Costa M., Maffei L., Pizzorusso T. Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity. Neuron 2007, 53(5):747-759.
    • (2007) Neuron , vol.53 , Issue.5 , pp. 747-759
    • Putignano, E.1    Lonetti, G.2    Cancedda, L.3    Ratto, G.4    Costa, M.5    Maffei, L.6    Pizzorusso, T.7
  • 54
    • 2942515687 scopus 로고    scopus 로고
    • Genesis of neocortex in human and nonhuman primates
    • Lippincott Williams & Wilkins, Philadelphia, M. Lewis (Ed.)
    • Rakic P. Genesis of neocortex in human and nonhuman primates. Child and Adolescent Psychiatry: A Comprehensive Textbook 2002, 22-46. Lippincott Williams & Wilkins, Philadelphia. M. Lewis (Ed.).
    • (2002) Child and Adolescent Psychiatry: A Comprehensive Textbook , pp. 22-46
    • Rakic, P.1
  • 55
    • 40849139253 scopus 로고    scopus 로고
    • Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to VPA
    • Rinaldi T., Silberberg G., Markram H. Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to VPA. Cerebral Cortex 2008, 18:763-770.
    • (2008) Cerebral Cortex , vol.18 , pp. 763-770
    • Rinaldi, T.1    Silberberg, G.2    Markram, H.3
  • 56
    • 33845638793 scopus 로고    scopus 로고
    • The frequency of reversible parkinsonism and cognitive decline associated with valproate treatment: a study of 364 patients with different types of epilepsy
    • Ristić A.J., Vojvodić N., Janković S., Sindelić A., Sokić D. The frequency of reversible parkinsonism and cognitive decline associated with valproate treatment: a study of 364 patients with different types of epilepsy. Epilepsia 2006, 47(12):2183-2185.
    • (2006) Epilepsia , vol.47 , Issue.12 , pp. 2183-2185
    • Ristić, A.J.1    Vojvodić, N.2    Janković, S.3    Sindelić, A.4    Sokić, D.5
  • 57
    • 35248894933 scopus 로고    scopus 로고
    • The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees?
    • Rosenberg G. The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees?. Cellular and Molecular Life Sciences 2007, 64:2090-2103.
    • (2007) Cellular and Molecular Life Sciences , vol.64 , pp. 2090-2103
    • Rosenberg, G.1
  • 58
    • 61649112904 scopus 로고    scopus 로고
    • When does age-related cognitive decline begin?
    • Salthouse T.A. When does age-related cognitive decline begin?. Neurobiology of Aging 2009, 30(4):507-514.
    • (2009) Neurobiology of Aging , vol.30 , Issue.4 , pp. 507-514
    • Salthouse, T.A.1
  • 60
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • Shen S., Li J., Casaccia-Bonnefil P. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. Journal of Cell Biology 2005, 169:577-589.
    • (2005) Journal of Cell Biology , vol.169 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 61
  • 62
    • 7244242243 scopus 로고    scopus 로고
    • Longer term outcome of children born to mothers with epilepsy
    • Shorvon S.D. Longer term outcome of children born to mothers with epilepsy. Journal of Neurology, Neurosurgery and Psychiatry 2004, 75(11):1517-1518.
    • (2004) Journal of Neurology, Neurosurgery and Psychiatry , vol.75 , Issue.11 , pp. 1517-1518
    • Shorvon, S.D.1
  • 63
    • 0037213521 scopus 로고    scopus 로고
    • Interlaminar connections in the neocortex
    • Thomson A.M., Bannister A.P. Interlaminar connections in the neocortex. Cerebral Cortex 2003, 13(1):5-14.
    • (2003) Cerebral Cortex , vol.13 , Issue.1 , pp. 5-14
    • Thomson, A.M.1    Bannister, A.P.2
  • 67
    • 34447107097 scopus 로고    scopus 로고
    • Deficit of perineuronal oligodendrocytes in the prefrontal cortex in schizophrenia and mood disorders
    • Vostrikov V.M., Uranova N.A., Orlovskaya D.D. Deficit of perineuronal oligodendrocytes in the prefrontal cortex in schizophrenia and mood disorders. Schizophrenia Research 2007, 94:273-280.
    • (2007) Schizophrenia Research , vol.94 , pp. 273-280
    • Vostrikov, V.M.1    Uranova, N.A.2    Orlovskaya, D.D.3
  • 68
    • 84856082855 scopus 로고    scopus 로고
    • Abnormalities in thalamic neurophysiology in schizophrenia: could psychosis be a result of potassium channel dysfunction?
    • Vukadinovic Z., Rosenzweig I. Abnormalities in thalamic neurophysiology in schizophrenia: could psychosis be a result of potassium channel dysfunction?. Neuroscience and Biobehavioral Reviews 2012, 36(2):960-968.
    • (2012) Neuroscience and Biobehavioral Reviews , vol.36 , Issue.2 , pp. 960-968
    • Vukadinovic, Z.1    Rosenzweig, I.2
  • 70
  • 71
    • 77954003526 scopus 로고    scopus 로고
    • Shaping the oligodendrocyte identity by epigenetic control
    • Yu Y., Casaccia P., Lu Q.R. Shaping the oligodendrocyte identity by epigenetic control. Epigenetics 2010, 5:124-128.
    • (2010) Epigenetics , vol.5 , pp. 124-128
    • Yu, Y.1    Casaccia, P.2    Lu, Q.R.3
  • 72
    • 76749126263 scopus 로고    scopus 로고
    • Ascorbic acid reverses valproic acid-induced inhibition of hoxa2 and maintains glutathione homeostasis in mouse embryos in culture
    • Zhang B., Wang X., Nazarali A.J. Ascorbic acid reverses valproic acid-induced inhibition of hoxa2 and maintains glutathione homeostasis in mouse embryos in culture. Cellular and Molecular Neurobiology 2010, 30:137-148.
    • (2010) Cellular and Molecular Neurobiology , vol.30 , pp. 137-148
    • Zhang, B.1    Wang, X.2    Nazarali, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.