Ascorbic acid reverses valproic acid-induced inhibition of hoxa2 and maintains glutathione homeostasis in mouse embryos in culture

Cellular and Molecular Neurobiology

Volumn 30, Issue 1, 2010, Pages 137-148

  Zhang, B ^a,b   Wang, X ^a   Nazarali, A J ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b LANZHOU UNIVERSITY   (China)

Author keywords

Ascorbic acid; Glutathione; GSSG GSH; Hoxa2; Valproic acid; Whole embryo culture

Indexed keywords

ASCORBIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXA2; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; EMBRYO; EMBRYO GROWTH; FEMALE; GENE EXPRESSION; MALE; MOUSE; MOUSE EMBRYO; NEURAL TUBE DEFECT; NONHUMAN; ORGANOGENESIS; OXIDATIVE STRESS; PRIORITY JOURNAL; TERATOGENESIS;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; EMBRYO CULTURE TECHNIQUES; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTATHIONE; HOMEODOMAIN PROTEINS; HOMEOSTASIS; MICE; MODELS, BIOLOGICAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VALPROIC ACID;

MUS;

EID: 76749126263     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-009-9438-7     Document Type: Article

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