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Volumn 80, Issue 7, 2012, Pages 2307-2315

Enterohemorrhagic escherichia coli O157:H7 shiga toxins inhibit gamma interferon-mediated cellular activation

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; GAMMA INTERFERON; SHIGA TOXIN; STAT1 PROTEIN; TYROSINE;

EID: 84864801038     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00255-12     Document Type: Article
Times cited : (17)

References (50)
  • 1
    • 0036081273 scopus 로고    scopus 로고
    • Bicarbonate ion stimulates the expression of locus of enterocyte effacement-encoded genes in enterohemorrhagic Escherichia coli O157: H7
    • Abe H, Tatsuno I, Tobe T, Okutani A, Sasakawa C. 2002. Bicarbonate ion stimulates the expression of locus of enterocyte effacement-encoded genes in enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 70: 3500-3509.
    • (2002) Infect. Immun. , vol.70 , pp. 3500-3509
    • Abe, H.1    Tatsuno, I.2    Tobe, T.3    Okutani, A.4    Sasakawa, C.5
  • 2
    • 0033833415 scopus 로고    scopus 로고
    • Use of a Shiga toxin (Stx)-enzyme-linked immunosorbent assay and immunoblot for detection and isolation of Stx-producing Escherichia coli from naturally contaminated beef
    • Atalla HN, Johnson R, McEwen S, Usborne RW, Gyles CL. 2000. Use of a Shiga toxin (Stx)-enzyme-linked immunosorbent assay and immunoblot for detection and isolation of Stx-producing Escherichia coli from naturally contaminated beef. J. Food Prot. 63:1167-1172.
    • (2000) J. Food Prot. , vol.63 , pp. 1167-1172
    • Atalla, H.N.1    Johnson, R.2    McEwen, S.3    Usborne, R.W.4    Gyles, C.L.5
  • 4
    • 69749128439 scopus 로고    scopus 로고
    • Enterohemorrhagic Escherichia coli suppresses inflammatory response to cytokines and its own toxin
    • Bellmeyer A, et al. 2009. Enterohemorrhagic Escherichia coli suppresses inflammatory response to cytokines and its own toxin. Am. J. Physiol. Gastrointest. Liver Physiol. 297:G576 -581.
    • (2009) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.297
    • Bellmeyer, A.1
  • 5
    • 80051804184 scopus 로고    scopus 로고
    • Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study
    • Bielaszewska M, et al. 2011. Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study. Lancet Infect. Dis. 11:671- 676.
    • (2011) Lancet Infect. Dis. , vol.11 , pp. 671-676
    • Bielaszewska, M.1
  • 6
    • 0037372652 scopus 로고    scopus 로고
    • Enterohemorrhagic Escherichia coli O157: H7 disrupts Stat1-mediated gamma interferon signal transduction in epithelial cells
    • Ceponis PJ, McKay DM, Ching JC, Pereira P, Sherman PM. 2003. Enterohemorrhagic Escherichia coli O157:H7 disrupts Stat1-mediated gamma interferon signal transduction in epithelial cells. Infect. Immun. 71:1396 -1404.
    • (2003) Infect. Immun. , vol.71 , pp. 1396-1404
    • Ceponis, P.J.1    McKay, D.M.2    Ching, J.C.3    Pereira, P.4    Sherman, P.M.5
  • 7
    • 33645787761 scopus 로고    scopus 로고
    • Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo
    • Chapgier A, et al. 2006. Human complete Stat-1 deficiency is associated with defective type I and II IFN responses in vitro but immunity to some low virulence viruses in vivo. J. Immunol. 176:5078 -5083.
    • (2006) J. Immunol. , vol.176 , pp. 5078-5083
    • Chapgier, A.1
  • 8
    • 0031965461 scopus 로고    scopus 로고
    • Detection of verotoxigenic Escherichia coli by magnetic capture-hybridization PCR
    • Chen J, Johnson R, Griffiths M. 1998. Detection of verotoxigenic Escherichia coli by magnetic capture-hybridization PCR. Appl. Environ. Microbiol. 64:147-152.
    • (1998) Appl. Environ. Microbiol. , vol.64 , pp. 147-152
    • Chen, J.1    Johnson, R.2    Griffiths, M.3
  • 9
    • 0036070836 scopus 로고    scopus 로고
    • Escherichia coli Shiga-like toxins induce apoptosis and cleavage of poly-(ADP-ribose) polymerase via in vitro activation of caspases
    • Ching JC, Jones NL, Ceponis PJ, Karmali MA, Sherman PM. 2002. Escherichia coli Shiga-like toxins induce apoptosis and cleavage of poly-(ADP-ribose) polymerase via in vitro activation of caspases. Infect. Immun. 70:4669-4677.
    • (2002) Infect. Immun. , vol.70 , pp. 4669-4677
    • Ching, J.C.1    Jones, N.L.2    Ceponis, P.J.3    Karmali, M.A.4    Sherman, P.M.5
  • 10
    • 73949118739 scopus 로고    scopus 로고
    • Molecular mechanisms of Escherichia coli pathogenicity
    • Croxen MA, Finlay BB. 2010. Molecular mechanisms of Escherichia coli pathogenicity. Nat. Rev. Microbiol. 8:26 -38.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 26-38
    • Croxen, M.A.1    Finlay, B.B.2
  • 11
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. U. S. A. 97:6640-6645.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 12
    • 59849113939 scopus 로고    scopus 로고
    • The effector repertoire of enteropathogenic E. coli: ganging up on the host cell
    • Dean P, Kenny B. 2009. The effector repertoire of enteropathogenic E. coli: ganging up on the host cell. Curr. Opin. Microbiol. 12:101-109.
    • (2009) Curr. Opin. Microbiol. , vol.12 , pp. 101-109
    • Dean, P.1    Kenny, B.2
  • 13
    • 0032731094 scopus 로고    scopus 로고
    • The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation
    • Didcock L, Young DF, Goodbourn S, Randall RE. 1999. The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation. J. Virol. 73:9928 -9933.
    • (1999) J. Virol. , vol.73 , pp. 9928-9933
    • Didcock, L.1    Young, D.F.2    Goodbourn, S.3    Randall, R.E.4
  • 15
    • 0037371835 scopus 로고    scopus 로고
    • Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency
    • Dupuis S, et al. 2003. Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency. Nat. Genet. 33:388 -391.
    • (2003) Nat. Genet. , vol.33 , pp. 388-391
    • Dupuis, S.1
  • 16
    • 80955168000 scopus 로고    scopus 로고
    • Epidemic profile of Shiga-toxin-producing Escherichia coli O104: H4 outbreak in germany-preliminary report
    • Frank C, et al. 2011. Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in germany-preliminary report. N. Engl. J. Med. 365:1771-1780.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1771-1780
    • Frank, C.1
  • 17
    • 78650869572 scopus 로고    scopus 로고
    • Enterohemorrhagic Escherichia coli induce attaching and effacing lesions and hemorrhagic colitis in human and bovine intestinal xenograft models
    • Golan L, Gonen E, Yagel S, Rosenshine I, Shpigel NY. 2011. Enterohemorrhagic Escherichia coli induce attaching and effacing lesions and hemorrhagic colitis in human and bovine intestinal xenograft models. Dis. Model Mech. 4:86 -94.
    • (2011) Dis. Model Mech. , vol.4 , pp. 86-94
    • Golan, L.1    Gonen, E.2    Yagel, S.3    Rosenshine, I.4    Shpigel, N.Y.5
  • 18
    • 77954074182 scopus 로고    scopus 로고
    • An efficient stress-free strategy to displace stable bacterial plasmids
    • Hale L, Lazos O, Haines A, Thomas C. 2010. An efficient stress-free strategy to displace stable bacterial plasmids. Biotechniques 48:223-228.
    • (2010) Biotechniques , vol.48 , pp. 223-228
    • Hale, L.1    Lazos, O.2    Haines, A.3    Thomas, C.4
  • 19
    • 77952697123 scopus 로고    scopus 로고
    • Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagic Escherichia coli: a case for EspB as an intrinsically less-ordered effector
    • Hamada D, Hamaguchi M, Suzuki KN, Sakata I, Yanagihara I. 2010. Cytoskeleton-modulating effectors of enteropathogenic and enterohemorrhagic Escherichia coli: a case for EspB as an intrinsically less-ordered effector. FEBS J. 277:2409 -2415.
    • (2010) FEBS J , vol.277 , pp. 2409-2415
    • Hamada, D.1    Hamaguchi, M.2    Suzuki, K.N.3    Sakata, I.4    Yanagihara, I.5
  • 20
    • 0033597901 scopus 로고    scopus 로고
    • Role of bacterial intimin in colonic hyperplasia and inflammation
    • Higgins LM, et al. 1999. Role of bacterial intimin in colonic hyperplasia and inflammation. Science 285:588 -591.
    • (1999) Science , vol.285 , pp. 588-591
    • Higgins, L.M.1
  • 21
    • 84855681899 scopus 로고    scopus 로고
    • Identifying mechanisms by which Escherichia coli O157: H7 subverts interferon-gamma mediated signal transducer and activator of transcription-1 activation
    • doi: 10.1371/journal.pone.00301457
    • Ho NK, Crandall I, Sherman PM. 2012. Identifying mechanisms by which Escherichia coli O157:H7 subverts interferon-gamma mediated signal transducer and activator of transcription-1 activation. PLoS One 7:e30145. doi:10.1371/journal.pone.0030145.
    • (2012) PLoS One
    • Ho, N.K.1    Crandall, I.2    Sherman, P.M.3
  • 22
    • 78049422962 scopus 로고    scopus 로고
    • The EspF effector, a bacterial pathogen's Swiss army knife
    • Holmes A, Muhlen S, Roe AJ, Dean P. 2010. The EspF effector, a bacterial pathogen's Swiss army knife. Infect. Immun. 78:4445- 4453.
    • (2010) Infect. Immun. , vol.78 , pp. 4445-4453
    • Holmes, A.1    Muhlen, S.2    Roe, A.J.3    Dean, P.4
  • 23
    • 0022615278 scopus 로고
    • Cloning and expression of the genes specifying Shiga-like toxin production in Escherichia coli H19
    • Huang A, et al. 1986. Cloning and expression of the genes specifying Shiga-like toxin production in Escherichia coli H19. J. Bacteriol. 166:375- 379.
    • (1986) J. Bacteriol. , vol.166 , pp. 375-379
    • Huang, A.1
  • 24
    • 33644749140 scopus 로고    scopus 로고
    • Conditioned medium from enterohemorrhagic Escherichia coli-infected T84 cells inhibits signal transducer and activator of transcription 1 activation by gamma interferon
    • Jandu N, et al. 2006. Conditioned medium from enterohemorrhagic Escherichia coli-infected T84 cells inhibits signal transducer and activator of transcription 1 activation by gamma interferon. Infect. Immun. 74: 1809-1818.
    • (2006) Infect. Immun. , vol.74 , pp. 1809-1818
    • Jandu, N.1
  • 25
    • 62849084810 scopus 로고    scopus 로고
    • Enterohemorrhagic Escherichia coli O157: H7 gene expression profiling in response to growth in the presence of host epithelia
    • doi: 10.1371/journal.pone.00048894
    • Jandu N, et al. 2009. Enterohemorrhagic Escherichia coli O157:H7 gene expression profiling in response to growth in the presence of host epithelia. PLoS One 4:e4889. doi:10.1371/journal.pone.0004889.
    • (2009) PLoS One
    • Jandu, N.1
  • 26
    • 33847149223 scopus 로고    scopus 로고
    • Multiple seropathotypes of verotoxin-producing Escherichia coli (VTEC) disrupt interferon-gamma-induced tyrosine phosphorylation of signal transducer and activator of transcription (Stat)-1
    • Jandu N, et al. 2007. Multiple seropathotypes of verotoxin-producing Escherichia coli (VTEC) disrupt interferon-gamma-induced tyrosine phosphorylation of signal transducer and activator of transcription (Stat)-1. Microb. Pathog. 42:62-71.
    • (2007) Microb. Pathog. , vol.42 , pp. 62-71
    • Jandu, N.1
  • 27
    • 79954767134 scopus 로고    scopus 로고
    • Recognition of bacterial pathogens and mucosal immunity
    • Jones RM, Neish AS. 2011. Recognition of bacterial pathogens and mucosal immunity. Cell. Microbiol. 13:670-676.
    • (2011) Cell. Microbiol. , vol.13 , pp. 670-676
    • Jones, R.M.1    Neish, A.S.2
  • 28
    • 10744231312 scopus 로고    scopus 로고
    • Association of genomic O island 122 of Escherichia coli EDL 933 with verocytotoxin-producing Escherichia coli seropathotypes that are linked to epidemic and/or serious disease
    • Karmali MA, et al. 2003. Association of genomic O island 122 of Escherichia coli EDL 933 with verocytotoxin-producing Escherichia coli seropathotypes that are linked to epidemic and/or serious disease. J. Clin. Microbiol. 41:4930-4940.
    • (2003) J. Clin. Microbiol. , vol.41 , pp. 4930-4940
    • Karmali, M.A.1
  • 29
    • 79960087844 scopus 로고    scopus 로고
    • Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104: H4 in the Netherlands, May 2011
    • pii
    • Kuijper EJ, Soonawala D, Vermont C, van Dissel JT. 2011. Household transmission of haemolytic uraemic syndrome associated with Escherichia coli O104:H4 in the Netherlands, May 2011. Euro Surveill. 16:pii:19897.
    • (2011) Euro Surveill , vol.16 , pp. 19897
    • Kuijper, E.J.1    Soonawala, D.2    Vermont, C.3    van Dissel, J.T.4
  • 30
    • 77349097325 scopus 로고    scopus 로고
    • Shiga toxin 1-induced inflammatory response in lipopolysaccharide-sensitized astrocytes is mediated by endogenous tumor necrosis factor alpha
    • Landoni VI, et al. 2010. Shiga toxin 1-induced inflammatory response in lipopolysaccharide-sensitized astrocytes is mediated by endogenous tumor necrosis factor alpha. Infect. Immun. 78:1193-1201.
    • (2010) Infect. Immun. , vol.78 , pp. 1193-1201
    • Landoni, V.I.1
  • 31
    • 0023664612 scopus 로고
    • Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro
    • Lingwood CA, et al. 1987. Glycolipid binding of purified and recombinant Escherichia coli produced verotoxin in vitro. J. Biol. Chem. 262:8834- 8839.
    • (1987) J. Biol. Chem. , vol.262 , pp. 8834-8839
    • Lingwood, C.A.1
  • 32
    • 77349100136 scopus 로고    scopus 로고
    • Associations between mucosal innate and adaptive immune responses and resolution of diarrheal pathogen infections
    • Long KZ, et al. 2010. Associations between mucosal innate and adaptive immune responses and resolution of diarrheal pathogen infections. Infect. Immun. 78:1221-1228.
    • (2010) Infect. Immun. , vol.78 , pp. 1221-1228
    • Long, K.Z.1
  • 33
    • 43549120469 scopus 로고    scopus 로고
    • Latrunculin B facilitates Shiga toxin 1 transcellular transcytosis across T84 intestinal epithelial cells
    • Maluykova I, et al. 2008. Latrunculin B facilitates Shiga toxin 1 transcellular transcytosis across T84 intestinal epithelial cells. Biochim. Biophys. Acta 1782:370 -377.
    • (2008) Biochim. Biophys. Acta , vol.1782 , pp. 370-377
    • Maluykova, I.1
  • 34
    • 0028827229 scopus 로고
    • Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1
    • Nandan D, Reiner NE. 1995. Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat1. Infect. Immun. 63:4495- 4500.
    • (1995) Infect. Immun. , vol.63 , pp. 4495-4500
    • Nandan, D.1    Reiner, N.E.2
  • 35
    • 79952087639 scopus 로고    scopus 로고
    • Escherichia coli Shiga toxin mechanisms of action in renal disease
    • Obrig TG. 2010. Escherichia coli Shiga toxin mechanisms of action in renal disease. Toxins (Basel) 2:2769 -2794.
    • (2010) Toxins (Basel) , vol.2 , pp. 2769-2794
    • Obrig, T.G.1
  • 36
    • 44649129135 scopus 로고    scopus 로고
    • Commensals, bacterial pathogens and intestinal inflammation: an intriguing menage a trois
    • Pedron T, Sansonetti P. 2008. Commensals, bacterial pathogens and intestinal inflammation: an intriguing menage a trois. Cell Host Microbe 3:344 -347.
    • (2008) Cell Host Microbe , vol.3 , pp. 344-347
    • Pedron, T.1    Sansonetti, P.2
  • 37
    • 0026755585 scopus 로고
    • Characterization of the enterocytelike brush border cytoskeleton of the C2BBe clones of the human intestinal cell line
    • Peterson MD, Mooseker MS. 1992. Characterization of the enterocytelike brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2. J. Cell Sci. 102:581- 600.
    • (1992) Caco-2. J. Cell Sci. , vol.102 , pp. 581-600
    • Peterson, M.D.1    Mooseker, M.S.2
  • 38
    • 0030007493 scopus 로고    scopus 로고
    • Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions
    • Philpott DJ, McKay DM, Sherman PM, Perdue MH. 1996. Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functions. Am. J. Physiol. 270:G634-645.
    • (1996) Am. J. Physiol. , vol.270
    • Philpott, D.J.1    McKay, D.M.2    Sherman, P.M.3    Perdue, M.H.4
  • 39
    • 80052150179 scopus 로고    scopus 로고
    • Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany
    • Rasko DA, et al. 2011. Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. N. Engl. J. Med. 365:709 -717.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 709-717
    • Rasko, D.A.1
  • 40
    • 0026989386 scopus 로고
    • Bacterial endotoxins
    • Rietschel ET, Brade H. 1992. Bacterial endotoxins. Sci. Am. 267:54-61.
    • (1992) Sci. Am. , vol.267 , pp. 54-61
    • Rietschel, E.T.1    Brade, H.2
  • 41
    • 0027253760 scopus 로고
    • The chemical structure of bacterial endotoxin in relation to bioactivity
    • Rietschel ET, et al. 1993. The chemical structure of bacterial endotoxin in relation to bioactivity. Immunobiology 187:169 -190.
    • (1993) Immunobiology , vol.187 , pp. 169-190
    • Rietschel, E.T.1
  • 42
    • 27744584137 scopus 로고    scopus 로고
    • Cholesterol-enriched membrane microdomains are required for inducing host cell cytoskeleton rearrangements in response to attaching-effacing Escherichia coli
    • Riff JD, Callahan JW, Sherman PM. 2005. Cholesterol-enriched membrane microdomains are required for inducing host cell cytoskeleton rearrangements in response to attaching-effacing Escherichia coli. Infect. Immun. 73:7113-7125.
    • (2005) Infect. Immun. , vol.73 , pp. 7113-7125
    • Riff, J.D.1    Callahan, J.W.2    Sherman, P.M.3
  • 43
    • 77049092286 scopus 로고    scopus 로고
    • Gene modulation and immunoregulatory roles of interferon gamma
    • Saha B, Jyothi Prasanna S, Chandrasekar B, Nandi D. 2010. Gene modulation and immunoregulatory roles of interferon gamma. Cytokine 50:1-14.
    • (2010) Cytokine , vol.50 , pp. 1-14
    • Saha, B.1    Jyothi Prasanna, S.2    Chandrasekar, B.3    Nandi, D.4
  • 44
    • 0842266786 scopus 로고    scopus 로고
    • Interferon-gamma: an overview of signals, mechanisms and functions
    • Schroder K, Hertzog PJ, Ravasi T, Hume DA. 2004. Interferon-gamma: an overview of signals, mechanisms and functions. J. Leukoc. Biol. 75:163- 189.
    • (2004) J. Leukoc. Biol. , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 45
    • 77957662987 scopus 로고    scopus 로고
    • Enteric pathogens and gut function: role of cytokines and STATs
    • Shea-Donohue T, Fasano A, Smith A, Zhao A. 2010. Enteric pathogens and gut function: role of cytokines and STATs. Gut Microbes 1:316 -324.
    • (2010) Gut Microbes , vol.1 , pp. 316-324
    • Shea-Donohue, T.1    Fasano, A.2    Smith, A.3    Zhao, A.4
  • 46
    • 33645068847 scopus 로고    scopus 로고
    • A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis
    • Spears KJ, Roe AJ, Gally DL. 2006. A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis. FEMS Microbiol. Lett. 255:187-202.
    • (2006) FEMS Microbiol. Lett. , vol.255 , pp. 187-202
    • Spears, K.J.1    Roe, A.J.2    Gally, D.L.3
  • 47
    • 0033806734 scopus 로고    scopus 로고
    • Isolation and characterization of mini-Tn5Km2 insertion mutants of enterohemorrhagic Escherichia coli O157: H7 deficient in adherence to Caco-2 cells
    • Tatsuno I, et al. 2000. Isolation and characterization of mini-Tn5Km2 insertion mutants of enterohemorrhagic Escherichia coli O157:H7 deficient in adherence to Caco-2 cells. Infect. Immun. 68:5943-5952.
    • (2000) Infect. Immun. , vol.68 , pp. 5943-5952
    • Tatsuno, I.1
  • 48
    • 0027959715 scopus 로고
    • Purified Shiga-like toxins induce expression of proinflammatory cytokines from murine peritoneal macrophages
    • Tesh VL, Ramegowda B, Samuel JE. 1994. Purified Shiga-like toxins induce expression of proinflammatory cytokines from murine peritoneal macrophages. Infect. Immun. 62:5085-5094.
    • (1994) Infect. Immun , vol.62 , pp. 5085-5094
    • Tesh, V.L.1    Ramegowda, B.2    Samuel, J.E.3
  • 49
    • 79958804398 scopus 로고    scopus 로고
    • Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements
    • Wong AR, et al. 2011. Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements. Mol. Microbiol. 80:1420- 1438.
    • (2011) Mol. Microbiol. , vol.80 , pp. 1420-1438
    • Wong, A.R.1
  • 50
    • 47749099379 scopus 로고    scopus 로고
    • Genotypic characterization and prevalence of virulence factors among Canadian Escherichia coli O157: H7 strains
    • Ziebell K, et al. 2008. Genotypic characterization and prevalence of virulence factors among Canadian Escherichia coli O157:H7 strains. Appl. Environ. Microbiol. 74:4314-4323.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 4314-4323
    • Ziebell, K.1


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