Anticancer mechanisms of action of two small amphipathic β 2,2-amino acid derivatives derived from antimicrobial peptides

Biochimica et Biophysica Acta - Biomembranes

Volumn 1818, Issue 11, 2012, Pages 2917-2925

  Ausbacher, Dominik ^a   Svineng, Gunbjørg ^a   Hansen, Terkel ^a   Strøm, Morten B ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Anticancer peptide; Antimicrobial peptide; Apoptosis; Beta amino acid; Caspases; Mitochondria

Indexed keywords

ANTINEOPLASTIC AGENT; BAA 1 PEPTIDE; BAA 2 PEPTIDE; CASPASE; CASPASE 10; CASPASE 2; CASPASE 3; CASPASE 4; CASPASE 5; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOCORTIN 5; POLYPEPTIDE ANTIBIOTIC AGENT; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BURKITT LYMPHOMA; CANCER CELL CULTURE; CANCER INHIBITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; IC 50; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

ANTI-INFECTIVE AGENTS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL LINE; FLOW CYTOMETRY; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIALS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; NECROSIS; PEPTIDES;

EID: 84864797143     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.07.005     Document Type: Article

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