A cationic amphiphilic peptide ABP-CM4 exhibits selective cytotoxicity against leukemia cells

Peptides

Volumn 31, Issue 8, 2010, Pages 1504-1510

  Chen, Yu Qing ^a   Min, Cui ^a   Sang, Ming ^a   Han, Yang Yang ^a   Ma, Xiao ^a   Xue, Xiao Qing ^a   Zhang, Shuang Quan ^a  

^a NANJING NORMAL UNIVERSITY   (China)

Author keywords

ABP CM4; Cytotoxicity; FITC labeling; Leukemia; Selectivity

Indexed keywords

ANTILEUKEMIC AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; ARGINYLTRYPTOPHYLLYSYLISOLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLUTAMYLLYSYLVALYLGLYCYLGLUTAMINYLASPARAGINYLISOLEUCYLARGINYLASPARTYLGLYCYLISOLEUCYLVALYLLYSYLALANYLGLYCYLPROLYLALANYLVALYLALANYLVALYLVALYLGLYCYLGLUTAMINYLALANYLALANYLTHREONYLISOLEUCINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL STRAIN HEK293; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG BINDING; DRUG CONFORMATION; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SILKWORM;

BOMBYX MORI; MAMMALIA;

EID: 78249267530     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.05.010     Document Type: Article

References (36)

1. Bechinger B. Structure and functions of channel-forming peptides: magainins, cecropins, melittin and alamethicin. J Membr Biol 1997;156: 197-211.
2. Boman HG. Antibacterial peptides: basic facts and emerging concepts. J Intern Med 2003;254:197-215.
3. Boon JM, Smith BD. Chemical control of phospholipid distribution across bilayer membranes. Med Res Rev 2002;22:251-281
4. Chen YQ, Zhang SQ, Li BC, Qiu W, Jiao B, Zhang J, et al. Expression of a cytotoxic cationic antibacterial peptide in Escherichia coli using two fusion partners. Protein Expr Purif 2008;57:303-311
5. Dathe M, Wieprecht T. Structural features of helical antimicrobial peptides: their potential to modulate activity on model membranes and biological cells. Biochim Biophys Acta 1999;1462:71-87.
6. Deamer D, Bangham AD. Large volume liposomes by an ether vaporization method. Biochim Biophys Acta 1976;443:629-634
7. Dobrzynska I, Szachowicz-Petelska B, Sulkowski S, Figaszewski Z. Changes in electric charge and phospholipids composition in human colorectal cancer cells. Mol Cell Biochem 2005;276:113-119
8. Elissen LT, Haug BE, Berge G, Rekdal O. Enhanced antitumor activity of 15- residue bovine Lactoferricin derivatives containing bulky aromatic amino acids and lipophilic N-terminal modifications. J Pept Sci 2003;9:510-517
9. Gatti L, Zunino F. Overview of tumor cell chemoresistance mechanisms. Methods Mol Med 2005;111:127-148
10. Giuliani A, Pirri G, Bozzi A, Di Giulio A, Aschi M, Rinaldi AC. Antimicrobial peptides: natural templates for synthetic membrane-active compounds. Cell Mol Life Sci 2008;65:2450-2460
11. Hancock RE, Rozek A. Role of membranes in the activities of antimicrobial cationic peptides. FEMS Microbiol Lett 2002;206:143-149
12. Hancock RE, Sahl HG. Antimicrobial and host-defense peptides as new antiinfective therapeutic strategies. Nat Biotechnol 2006;24:1551-1557
13. Hoskin DW, Ramamoorthy A. Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta 2008;1778:357-375
14. Iwasaki T, Ishibashi J, Tanaka H, Sato M, Asaoka A, Taylor D, et al. Selective cancer cell cytotoxicity of enantiomeric 9-mer peptides derived from beetle defensins depends on negatively charged phosphatidylserine on the cell surface. Peptides 2009;30:660-668
15. Jin Z, Han YP, Zhang WH, Wang F, Zhang SQ, Mao YM. Ultrastructural observation of E. coli K12 treated with antibacterial peptide CM4. Acta Biol Exp Sinica 2000;33:89-95.
16. Lehmann J, Retz M, Sidhu SS, Suttmann H, Sell M, Paulsen F, et al. Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines. Eur Urol 2006;50:141-147
17. Li BC, Zhang SQ, Dan WB, Chen YQ, Cao P. Expression in Escherichia coli and purification of bioactive antibacterial peptide ABP-CM4 from the Chinese silk worm, Bombyx mori. Biotechnol Lett 2007;29:1031-1036
18. Lin QP, Zhou LF, Li NN, Chen YQ, Li BC, Cai YF, et al. Lipopolysaccharide neutralization by the antibacterial peptide CM4. Eur J Pharmacol 2008;596:160-165
19. Mookherjee N, Hancock REW. Cationic host defence peptides: innate immune regulatory peptides as a novel approach for treating infections. Cell Mol Life Sci 2007;64:922-933
20. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;659:55-63.
21. Papo N, Shai Y. Host defense peptides as new weapons in cancer treatment. Cell Mol Life Sci 2005;62:784-790
22. Risso A, Braidot E, Sordano MC, Vianello A, Macri F, Skerlavaj B, et al. BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol 2002;22:1926-1935
23. Schweizer F. Cationic amphiphilic peptides with cancer-selective toxicity. Eur J Pharmacol 2009;625:190-194
24. Sharma SV. Melittin-induced hyperactivation of phospholipase A2 activity and calcium influx in ras-transformed cells. Oncogene 1993;8:939-947
25. Sitaram N, Nagaraj R. Interaction of antimicrobial peptides with biological and model membranes: structural and charge requirements for activity. Biochim Biophys Acta 1999;1462:29-54.
26. Tu YZ, Zhang SQ, Qu XM. Separation, purification of antibacterial CM4 and the research of the structure and character. Sci Chin B 1989;32:473-480
27. Utsugi T, Schroit AJ, Connor J, Buccana CD, Fidler IJ. Elevated expression of phosphatidylserine in the outer leaflet of human tumor cells and recognition by activated human blood monocytes. Cancer Res 1991;51:3062-3066
28. Viejo-Diaz M, Andres MT, Fierro JF. Effects of human lactoferrin on the cytoplasmic membrane of Candida albicans cells related with its candidacidal activity. FEMS Immunol Med Microbiol 2004;42:181-185
29. Wu JM, Jan PS, Yu HC, Haing HY, Fang HJ, Chang YI, et al. Structure and function of a custom anticancer peptide, CB1a. Peptides 2009;30:839-884
30. Xu JS, Zhang SQ. The antibacterial mechanism of antibacterial peptide CM4 observed by confocal microscopy. Prog Nat Sci 2001;10:1105-1109
31. Yang N, Strøm MB, Mekonnen SM, Svendsen JS, Rekdal O. The effects of shortening lactoferrin derived peptides against tumour cells, bacteria and normal human cell. J Pept Sci 2004;10:37-46.
32. Yoon WH, Park HD, Lim K, Hwang BD. Effect of O-glycosylated mucin on invasion and metastasis of HM7 human colon cancer cells. Biochem Biophys Res Commun 1996;222:694-699
33. Yoo YC, Watanabe S, Watanabe R, Hala K, Shimazaki K, Azuma I. Bovine lactoferrin and lactoferricin, a peptide derived from bovine lactoferrin, inhibit tumor metastasis in mice. Jpn J Cancer Res 1997;88:184-190
34. Zaiou M. Multifunctional antimicrobial peptides: therapeutic targets in several human diseases. J Mol Med 2007;85:317-329
35. Zhang J, Wu X, Zhang SQ. Antifungal mechanism of antibacterial peptide, ABPCM4, from Bombyx mori against Aspergillus niger. Biotechnol Lett 2008;30: 2157-2163
36. Zhang J, Zhang SQ, Wu X, Chen YQ, Diao ZY. Expression and characterization of antimicrobial peptide ABP-CM4 in methylotrophic yeast Pichia pastoris. Process Biochem 2006;41:251-256