Platelets and cytokines: How and why?

Transfusion Clinique et Biologique

Volumn 19, Issue 3, 2012, Pages 104-108

  Garraud, O ^a,b,c   Hamzeh Cognasse, H ^b,c   Cognasse, F ^a,c  

^a ETABLISSEMENT FRANÇAIS DU SANG   (France)

^b UNIVERSITÉ JEAN MONNET   (France)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

Biological response modifiers; CD40L; Cytokines; Inflammation; Innate immunity; Platelets; Transfusion; Transfusion hazards

Indexed keywords

CD40 LIGAND; CYTOKINE; MYELOID DIFFERENTIATION FACTOR 88; THROMBOCYTE ANTIGEN; THROMBOCYTE CONCENTRATE; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6;

ANTIGEN PRESENTATION; BLOOD DONOR; CHILL; CYTOKINE PRODUCTION; FEVER; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; PATIENT SAFETY; RECIPIENT; RIGOR; SHORT SURVEY; THROMBOCYTE; THROMBOCYTE RELEASE REACTION; THROMBOCYTE TRANSFUSION; TRANSFUSION RELATED ACUTE LUNG INJURY;

BLOOD PLATELETS; CYTOKINES; HUMANS; PLATELET TRANSFUSION;

EID: 84864772134     PISSN: 12467820     EISSN: 19538022     Source Type: Journal    
DOI: 10.1016/j.tracli.2012.02.004     Document Type: Short Survey

References (72)

1. Semple J.W., Italiano J.E., Freedman J. Platelets and the immune continuum. Nat Rev Immunol 2011, 11:264-274.
2. Aird W.C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003, 101:3765-3777.
3. Blajchman M.A., Slichter S.J., Heddle N.M., Murphy M.F. New strategies for the optimal use of platelet transfusions. Hematology Am Soc Hematol Educ Program 2008, 198-204.
4. Andreu G., Vasse J., Tardivel R., Semana G. Platelet transfusion: products, indications, dose, threshold and efficacy. Transfus Clin Biol 2009, 16:118-133.
5. Heddle N.M., Klama L., Singer J., Richards C., Fedak P., Walker I., et al. The role of the plasma from platelet concentrates in transfusion reactions. N Engl J Med 1994, 331:625-628.
6. Stroncek D.F., Rebulla P. Platelet transfusions. Lancet 2007, 370:427-438.
7. Garraud O., Cognasse F. Platelet Toll-like receptor expression: the link between "danger" ligands and inflammation. Inflamm Allergy Drug Targets 2010, 9:322-333.
8. Garraud O., Berthet J., Hamzeh-Cognasse H., Cognasse F. Pathogen sensing, subsequent signalling, and signalosome in human platelets. Thromb Res 2011, 127:283-286.
9. Agence française de sécurité sanitaire des produits de santé (Afssaps) Rapport annuel hémovigilance 2010 2011, Afssaps, La Plaine-Saint-Denis, [Disponible à l'adresse: http://www.afssaps.fr/Afssaps-media/Publications/Bilans-Rapports-d-activite-Bilans-et-rapports-d-activite (accessed 29/2/2012)].
10. Phipps R.P., Kaufman J., Blumberg N. Platelet derived CD154 (CD40 ligand) and febrile responses to transfusion. Lancet 2001, 357:2023-2024.
11. Blumberg N., Gettings K.F., Turner C., Heal J.M., Phipps R.P. An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions. Transfusion 2006, 46:1813-1821.
12. Cognasse F., Payrat J.M., Corash L., Osselaer J.C., Garraud O. Platelet components associated with acute transfusion reactions: the role of platelet-derived soluble CD40 ligand. Blood 2008, 112:4779-4780.
13. Blumberg N., Spinelli S.L., Francis C.W., Taubman M.B., Phipps R.P. The platelet as an immune cell-CD40 ligand and transfusion immunomodulation. Immunol Res 2009, 45:251-260.
14. Cognasse F., Osselaer J.C., Garraud O. Platelets cytokines and their effects on platelet transfusion. Transfus Clin Biol 2007, 14:69-78.
15. Garraud O., Cognasse F. Platelet immunology and the immune response. Transfus Clin Biol 2009, 16:106-117.
16. Blair P., Flaumenhaft R. Platelet alpha-granules: basic biology and clinical correlates. Blood Rev 2009, 23:177-189.
17. Smith T.L., Weyrich A.S. Platelets as central mediators of systemic inflammatory responses. Thromb Res 2011, 127:391-394.
18. Jurk K., Kehrel B.E. Platelets: physiology and biochemistry. Semin Thromb Hemost 2005, 31:381-392.
19. Andrews R.K., Berndt M.C. Platelet physiology and thrombosis. Thromb Res 2004, 114:447-453.
20. Italiano J.E., Mairuhu A.T., Flaumenhaft R. Clinical relevance of microparticles from platelets and megakaryocytes. Curr Opin Hematol 2010, 17:578-584.
21. Stack G., Snyder E.L. Cytokine generation in stored platelet concentrates. Transfusion 1994, 34:20-25.
22. Macaulay I.C., Carr P., Gusnanto A., Ouwehand W.H., Fitzgerald D., Watkins N.A. Platelet genomics and proteomics in human health and disease. J Clin Invest 2005, 115:3370-3377.
23. Thon J.N., Schubert P., Devine D.V. Platelet storage lesion: a new understanding from a proteomic perspective. Transfus Med Rev 2008, 22:268-279.
24. Schubert P., Devine D.V. Proteomics meets blood banking: identification of protein targets for the improvement of platelet quality. J Proteomics 2010, 73:436-444.
25. Devine D.V., Serrano K. The platelet storage lesion. Clin Lab Med 2010, 30:475-487.
26. Cognasse F., Boussoulade F., Chavarin P., Acquart S., Fabrigli P., Lamy B., et al. Release of potential immunomodulatory factors during platelet storage. Transfusion 2006, 46:1184-1189.
27. Fong K.P., Barry C., Tran A.N., Traxler E.A., Wannemacher K.M., Tang H.Y., et al. Deciphering the human platelet sheddome. Blood 2011, 117:e15-e26.
28. Cooling L.L., Kelly K., Barton J., Hwang D., Koerner T.A., Olson J.D. Determinants of ABH expression on human blood platelets. Blood 2005, 105:3356-3364.
29. Rozman P. Platelet antigens. The role of human platelet alloantigens (HPA) in blood transfusion and transplantation. Transpl Immunol 2002, 10:165-181.
30. Blumberg N., Phipps R.P., Kaufman J., Heal J.M. The causes and treatment of reactions to platelet transfusions. Transfusion 2003, 43:291-292. [author reply 2].
31. Refaai M.A., Phipps R.P., Spinelli S.L., Blumberg N. Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomes. Thromb Res 2011, 127:287-291.
32. Khan S.Y., Kelher M.R., Heal J.M., Blumberg N., Boshkov L.K., Phipps R., et al. Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury. Blood 2006, 108:2455-2462.
33. Chavarin P., Cognasse F., Argaud C., Vidal M., De Putter C., Boussoulade F., et al. In vitro assessment of apheresis and pooled buffy coat platelet components suspended in plasma and SSP+ photochemically treated with amotosalen and UVA for pathogen inactivation (INTERCEPT Blood System). Vox Sang 2011, 100:247-249.
34. Fitzgerald J.R., Foster T.J., Cox D. The interaction of bacterial pathogens with platelets. Nat Rev Microbiol 2006, 4:445-457.
35. Clemetson K.J. Platelets and pathogens. Cell Mol Life Sci 2010, 67:495-498.
36. Yeaman M.R. Platelets in defense against bacterial pathogens. Cell Mol Life Sci 2010, 67:525-544.
37. Cognasse F., Hamzeh-Cognasse H., Garraud O. Platelets "Toll-like receptor" engagement stimulates the release of immunomodulating molecules. Transfus Clin Biol 2008, 15:139-147.
38. Cognasse F., Hamzeh H., Chavarin P., Acquart S., Genin C., Garraud O. Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol 2005, 83:196-198.
39. Shiraki R., Inoue N., Kawasaki S., Takei A., Kadotani M., Ohnishi Y., et al. Expression of Toll-like receptors on human platelets. Thromb Res 2004, 113:379-385.
40. Cox D., Kerrigan S.W., Watson S.P. Platelets and the innate immune system: mechanisms of bacterial-induced platelet activation. J Thromb Haemost 2011, 9:1097-1107.
41. Assinger A., Laky M., Schabbauer G., Hirschl A.M., Buchberger E., Binder B.R., et al. Efficient phagocytosis of periodontopathogens by neutrophils requires plasma factors, platelets and TLR2. J Thromb Haemost 2011, 9:799-809.
42. Keane C., Tilley D., Cunningham A., Smolenski A., Kadioglu A., Cox D., et al. Invasive Streptococcus pneumoniae trigger platelet activation via Toll-like receptor 2. J Thromb Haemost 2010, 8:2757-2765.
43. Kalvegren H., Skoglund C., Helldahl C., Lerm M., Grenegard M., Bengtsson T. Toll-like receptor 2 stimulation of platelets is mediated by purinergic P2X1-dependent Ca2+ mobilisation, cyclooxygenase and purinergic P2Y1 and P2Y12 receptor activation. Thromb Haemost 2010, 103:398-407.
44. Zhang G., Han J., Welch E.J., Ye R.D., Voyno-Yasenetskaya T.A., Malik A.B., et al. Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J Immunol 2009, 182:7997-8004.
45. Hashimoto K., Jayachandran M., Owen W.G., Miller V.M. Aggregation and microparticle production through toll-like receptor 4 activation in platelets from recently menopausal women. J Cardiovasc Pharmacol 2009, 54:57-62.
46. Shashkin P.N., Brown G.T., Ghosh A., Marathe G.K., McIntyre T.M. Lipopolysaccharide is a direct agonist for platelet RNA splicing. J Immunol 2008, 181:3495-3502.
47. Cognasse F., Hamzeh-Cognasse H., Lafarge S., Delezay O., Pozzetto B., McNicol A., et al. Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets. Br J Haematol 2008, 141:84-91.
48. Blair P., Rex S., Vitseva O., Beaulieu L., Tanriverdi K., Chakrabarti S., et al. Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. Circ Res 2008, 104:346-354.
49. Semple J.W., Aslam R., Kim M., Speck E.R., Freedman J. Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets. Blood 2007, 109:4803-4805.
50. Clark S.R., Ma A.C., Tavener S.A., McDonald B., Goodarzi Z., Kelly M.M., et al. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med 2007, 13:463-469.
51. Stahl A.L., Svensson M., Morgelin M., Svanborg C., Tarr P.I., Mooney J.C., et al. Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets via TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome. Blood 2006, 108:167-176.
52. Damas J.K., Jensenius M., Ueland T., Otterdal K., Yndestad A., Froland S.S., et al. Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets. J Immunol 2006, 177:2699-2706.
53. Aslam R., Speck E.R., Kim M., Crow A.R., Bang K.W., Nestel F.P., et al. Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-alpha production in vivo. Blood 2006, 107:637-641.
54. Andonegui G., Kerfoot S.M., McNagny K., Ebbert K.V., Patel K.D., Kubes P. Platelets express functional Toll-like receptor-4. Blood 2005, 106:2417-2423.
55. Brown G.T., McIntyre T.M. Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1beta-rich microparticles. J Immunol 2011, 186:5489-5496.
56. Berthet J., Damien P., Hamzeh-Cognasse H., Pozzetto B., Garraud O., Cognasse F. Toll-like receptor 4 signal transduction in platelets: novel pathways. Br J Haematol 2010, 151:89-92.
57. 2+ stores. Blood 2012, 119:3613-3621.
58. Liu F., Morris S., Epps J., Carroll R. Demonstration of an activation regulated NF-kappaB/I-kappaBalpha complex in human platelets. Thromb Res 2002, 106:199-203.
59. Spinelli S.L., Casey A.E., Pollock S.J., Gertz J.M., McMillan D.H., Narasipura S.D., et al. Platelets and megakaryocytes contain functional nuclear factor-{kappa}B. Arterioscler Thromb Vasc Biol 2010, 30:591-598.
60. Spinelli S.L., Maggirwar S.B., Blumberg N., Phipps R.P. Nuclear emancipation: a platelet tour de force. Sci Signal 2010, 3:pe37.
61. Sahler J., Bernard J.J., Spinelli S.L., Blumberg N., Phipps R.P. The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-kappaB inhibition. Thromb Res 2011, 127:426-434.
62. Rahman M., Zhang S., Chew M., Ersson A., Jeppsson B., Thorlacius H. Platelet-derived CD40L (CD154) mediates neutrophil upregulation of Mac-1 and recruitment in septic lung injury. Ann Surg 2009, 250:783-790.
63. Cognasse F., Osselaer J.C., Payrat J.M., Chavarin P., Corash L., Garraud O. Release of immune modulation factors from platelet concentrates during storage after photochemical pathogen inactivation treatment. Transfusion 2008, 48:809-813.
64. Cognasse F., Hamzeh-Cognasse H., Lafarge S., Chavarin P., Cogne M., Richard Y., et al. Human platelets can activate peripheral blood B cells and increase production of immunoglobulins. Exp Hematol 2007, 35:1376-1387.
65. Lee S.P., Ataga K.I., Orringer E.P., Phillips D.R., Parise L.V. Biologically active CD40 ligand is elevated in sickle cell anemia: potential role for platelet-mediated inflammation. Arterioscler Thromb Vasc Biol 2006, 26:1626-1631.
66. Nagasawa M., Zhu Y., Isoda T., Tomizawa D., Itoh S., Kajiwara M., et al. Analysis of serum soluble CD40 ligand (sCD40L) in the patients undergoing allogeneic stem cell transplantation: platelet is a major source of serum sCD40L. Eur J Haematol 2005, 74:54-60.
67. Langer F., Ingersoll S.B., Amirkhosravi A., Meyer T., Siddiqui F.A., Ahmad S., et al. The role of CD40 in CD40L- and antibody-mediated platelet activation. Thromb Haemost 2005, 93:1137-1146.
68. Chakrabarti S., Varghese S., Vitseva O., Tanriverdi K., Freedman J.E. CD40 ligand influences platelet release of reactive oxygen intermediates. Arterioscler Thromb Vasc Biol 2005, 25:2428-2434.
69. Harding S.A., Sommerfield A.J., Sarma J., Twomey P.J., Newby D.E., Frier B.M., et al. Increased CD40 ligand and platelet-monocyte aggregates in patients with type 1 diabetes mellitus. Atherosclerosis 2004, 176:321-325.
70. Prasad K.S., Andre P., He M., Bao M., Manganello J., Phillips D.R. Soluble CD40 ligand induces beta3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling. Proc Natl Acad Sci U S A 2003, 100:12367-12371.
71. Buchner K., Henn V., Grafe M., de Boer O.J., Becker A.E., Kroczek R.A. CD40 ligand is selectively expressed on CD4+ T cells and platelets: implications for CD40-CD40L signalling in atherosclerosis. J Pathol 2003, 201:288-295.
72. Henn V., Slupsky J.R., Grafe M., Anagnostopoulos I., Forster R., Muller-Berghaus G., et al. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature 1998, 391:591-594.